(Q41547386)

3 October 2017

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title

Mitochondrial dysfunction in neurodegeneration (English)

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3 October 2017

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2

Schapira AH

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3 October 2017

Cooper JM

1

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3 October 2017

publication date

1 April 1997

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Journal of Bioenergetics and Biomembranes

3 October 2017

published in

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3 October 2017

volume

29

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3 October 2017

issue

2

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3 October 2017

page(s)

175-183

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Choreoathetosis and striopallidonigral necrosis due to sodium azide

3 October 2017

cites work

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12 December 2020

Oxidative stress and mitochondrial dysfunction in neurodegeneration

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12 December 2020

Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease

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12 December 2020

Distinct clustering of point mutations in mitochondrial DNA among patients with mitochondrial encephalomyopathies and with Parkinson's disease

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12 December 2020

Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

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12 December 2020

Mitochondrial DNA in postmortem brain from patients with Parkinson's disease

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12 December 2020

Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence

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12 December 2020

L-dihydroxyphenylalanine and complex I deficiency in Parkinson's disease brain

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12 December 2020

1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism.

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12 December 2020

Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropanoic acid

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12 December 2020

Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy

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12 December 2020

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

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12 December 2020

Neocortical metabolic abnormalities precede nonmemory cognitive defects in early Alzheimer's-type dementia

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12 December 2020

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

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12 December 2020

MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or intranigral 1-methyl-4-phenylpyridinium in rats

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12 December 2020

Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease

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12 December 2020

Brain Cytochrome Oxidase in Alzheimer's Disease

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12 December 2020

Mitochondrial function in brain tissue in primary degenerative dementia.

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12 December 2020

Mitochondrial defect in Huntington's disease caudate nucleus

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12 December 2020

Progression after chronic manganese exposure

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12 December 2020

Clinical deterioration in probable Alzheimer's disease correlates with progressive metabolic impairment of association areas.

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12 December 2020

Selective inhibition of complex I by N-methylisoquinolinium ion and N-methyl-1,2,3,4-tetrahydroisoquinoline in isolated mitochondria prepared from mouse brain

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12 December 2020

Iron induced oxidative stress and mitochondrial dysfunction: relevance to Parkinson's disease

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12 December 2020

Intranigral iron injection induces behavioral and biochemical "parkinsonism" in rats

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12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro

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12 December 2020

Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility

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12 December 2020

Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)

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12 December 2020

Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+

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12 December 2020

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

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12 December 2020

Confirmation of the enantiomers of 1-methyl-1,2,3,4-tetrahydroisoquinoline in the mouse brain and foods applying gas chromatography/mass spectrometry with negative ion chemical ionization

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12 December 2020

A 31P magnetic resonance spectroscopy study of mitochondrial function in skeletal muscle of patients with Parkinson's disease

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12 December 2020

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

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12 December 2020

NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH–ubiquinone reductase preparation

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12 December 2020

Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat.

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12 December 2020

Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies

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12 December 2020

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

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12 December 2020

Cytotoxicity of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines

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12 December 2020

Malonate produces striatal lesions by indirect NMDA receptor activation

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12 December 2020

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

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12 December 2020

Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?

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12 December 2020

Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

18Fluorodeoxyglucose positron emission tomography studies in presumed Alzheimer cases, including 13 serial scans

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12 December 2020

Distribution of brain cytochrome oxidase activity in various neurodegenerative diseases

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12 December 2020

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

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12 December 2020

Electron transport chain defects in Alzheimer's disease brain

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12 December 2020

The cellular production of hydrogen peroxide

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12 December 2020

Origin and functional consequences of the complex I defect in Parkinson's disease

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12 December 2020

Mitochondrial respiratory chain inhibitors induce apoptosis.

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12 December 2020

Cyanide-induced parkinsonism: a clinicopathologic report

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12 December 2020

Inhibition of mitochondrial respiration by 1,2,3,4-tetrahydroisoquinoline-like endogenous alkaloids in mouse brain

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12 December 2020

1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol depletes catecholamines in rat brain

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12 December 2020

Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition

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12 December 2020

Generalized mitochondrial dysfunction in Parkinson's disease detected by magnetic resonance spectroscopy of muscle

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12 December 2020

An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions

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12 December 2020

Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons

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12 December 2020

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

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12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

Evidence that the inhibition sites of the neurotoxic amine 1-methyl-4-phenylpyridinium (MPP+) and of the respiratory chain inhibitor piericidin A are the same

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12 December 2020

Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): seven cases

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12 December 2020

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons

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12 December 2020

In vivo 31P NMR profiles of Alzheimer's disease and multiple subcortical infarct dementia.

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12 December 2020

Absence of the mitochondrial A7237T mutation in Parkinson's disease

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12 December 2020

Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation.

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12 December 2020

High-efficiency transformation of mammalian cells by plasmid DNA

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12 December 2020

Mitochondrial respiratory chain function in multiple system atrophy

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12 December 2020

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

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12 December 2020

Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity and ATP synthesis by tetrahydroisoquinoline

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12 December 2020

1‐Benzyl‐1,2,3,4‐Tetrahydroisoquinoline as a Parkinsonism‐Inducing Agent: A Novel Endogenous Amine in Mouse Brain and Parkinsonian CSF

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12 December 2020

Cortical cytochrome oxidase activity is reduced in Alzheimer's disease.

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12 December 2020

Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum

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12 December 2020

Mitochondrial function in Alzheimer's disease

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12 December 2020

Parkinsonism in monkeys produced by chronic administration of an endogenous substance of the brain, tetrahydroisoquinoline: the behavioral and biochemical changes

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12 December 2020

Evidence for mitochondrial dysfunction in Parkinson's disease--a critical appraisal

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12 December 2020

Topography of cross-sectional and longitudinal glucose metabolic deficits in Alzheimer's disease. Pathophysiologic implications

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12 December 2020

Cyanide-induced parkinsonism: clinical, MRI, and 6-fluorodopa PET studies

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12 December 2020

N-methylated tetrahydroisoquinolines as dopaminergic neurotoxins

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12 December 2020

A radical hypothesis for neurodegeneration

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12 December 2020

Age-dependent impairment of mitochondrial function in primate brain

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12 December 2020

Inhibition of mitochondrial succinate oxidation—Similarities and differences between N-methylated β-carbolines and MPP+

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12 December 2020

Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease

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12 December 2020

Inhibition of monoamine oxidase by isoquinoline derivatives. Qualitative and 3D-quantitative structure-activity relationships

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12 December 2020

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

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12 December 2020

Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease

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12 December 2020

Age‐Dependent Striatal Excitotoxic Lesions Produced by the Endogenous Mitochondrial Inhibitor Malonate

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12 December 2020

The N-methyl-D-aspartate antagonist MK-801 fails to protect dopaminergic neurons from 1-methyl-4-phenylpyridinium toxicity in vitro

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12 December 2020

Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration.

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12 December 2020

Mitochondrial DNA analysis in Parkinson's disease

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12 December 2020

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

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12 December 2020

Inhibition of α-Ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

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12 December 2020

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

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12 December 2020

Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

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12 December 2020

Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study

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12 December 2020

A mitochondrial DNA clone is associated with increased risk for Alzheimer disease

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12 December 2020

Correlation of morphologic brain lesions with physiologic alterations and blood-brain barrier impairment in 3-nitropropionic acid toxicity in rats

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12 December 2020

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

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12 December 2020

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

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12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity

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12 December 2020

Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain

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12 December 2020

Functional alterations in Alzheimer's disease: diminution of cytochrome oxidase in the hippocampal formation.

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12 December 2020

Positron emission tomography in Alzheimer's disease

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12 December 2020

Iron induces degeneration of nigrostriatal neurons

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12 December 2020

Is complex II involved in the inhibition of mitochondrial respiration by N-methyl-4-phenylpyridinium cation (MMP+) and N-methyl-beta-carbolines?

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12 December 2020

Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains

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12 December 2020

Identifiers

DOI

10.1023/A:1022642114734

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Dimensions Publication ID

3 October 2017

1022511704

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