(Q41239292)

28 September 2017

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title

Developmental regulation of V(D)J recombination and lymphocyte differentiation (English)

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28 September 2017

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Willerford DM

1

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28 September 2017

Swat W

series ordinal

2

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28 September 2017

Alt FW

series ordinal

3

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28 September 2017

publication date

1 October 1996

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Current Opinion in Genetics & Development

28 September 2017

published in

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28 September 2017

volume

6

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28 September 2017

issue

5

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28 September 2017

page(s)

603-609

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Gene rearrangement and B-cell development

28 September 2017

cites work

1 reference

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Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

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Control points in early T-cell development

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7 January 2021

V(D)J recombination: molecular biology and regulation

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RAG-1-deficient mice have no mature B and T lymphocytes

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

Initiation of V(D)J recombination in a cell-free system.

1 reference

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7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

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7 January 2021

Repair and Recombination: How to make ends meet

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7 January 2021

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

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7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

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7 January 2021

Potential targets for autosomal SCID mutations

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7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

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7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

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7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

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7 January 2021

Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

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7 January 2021

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

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7 January 2021

Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development

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7 January 2021

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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7 January 2021

Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation

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7 January 2021

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

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7 January 2021

A critical role of λ5 protein in B cell development

1 reference

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7 January 2021

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

1 reference

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7 January 2021

Analysis and expression of a cloned pre-T cell receptor gene

1 reference

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7 January 2021

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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7 January 2021

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus

1 reference

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7 January 2021

Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.

1 reference

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7 January 2021

T Cell Development in Mice that Lack the ζ Chain of the T Cell Antigen Receptor Complex

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7 January 2021

T cell development in mice lacking the CD3-zeta/eta gene.

1 reference

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7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1 reference

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7 January 2021

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

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7 January 2021

Defective B cell development and function in Btk-deficient mice

1 reference

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7 January 2021

Impaired expansion of mouse B cell progenitors lacking Btk.

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7 January 2021

Profound block in thymocyte development in mice lacking p56lck

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7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

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7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

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7 January 2021

The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c.

1 reference

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7 January 2021

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Interleukin-7: a Cofactor For V(D)J Rearrangement of the T Cell Receptor β Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Defective lymphoid development in mice lacking Jak3

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2896%2980090-6

7 January 2021

10.1016/S0959-437X(96)80090-6

Identifiers

DOI

1 reference

28 September 2017

1 reference