(Q41217536)

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Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.

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Europe PubMed Central

PubMed publication ID

28 September 2017

Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A. (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 September 2017

author name string

Merrick SE

1

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Europe PubMed Central

PubMed publication ID

28 September 2017

Demoise DC

2

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Europe PubMed Central

PubMed publication ID

28 September 2017

Lee VM

3

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Europe PubMed Central

PubMed publication ID

28 September 2017

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publication date

1 March 1996

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Europe PubMed Central

PubMed publication ID

28 September 2017

number of pages

6

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

28 September 2017

271

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Europe PubMed Central

PubMed publication ID

28 September 2017

10

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Europe PubMed Central

PubMed publication ID

28 September 2017

5589-5594

1 reference

Europe PubMed Central

PubMed publication ID

28 September 2017

The disordered neuronal cytoskeleton in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Structural characterization of the core of the paired helical filament of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

The carboxyl third of tau is tightly bound to paired helical filaments.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A protein factor essential for microtubule assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Tau protein binds to microtubules through a flexible array of distributed weak sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Identification and characterization of the ATP.Mg-dependent protein phosphatase activator (FA) as a microtubule protein kinase in the brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Promotion of microtubule assembly in vitro by taxol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Measurement of protein using bicinchoninic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

The distribution of tau in the mammalian central nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Immunological and conformation characterization of a phosphorylated immunodominant epitope on the paired helical filaments found in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Distribution of tau proteins in the normal human central and peripheral nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Epitopes that span the tau molecule are shared with paired helical filaments.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A neuronal antigen in the brains of Alzheimer patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Mapping of the Alz 50 epitope in microtubule-associated proteins tau

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase-2A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Domains of tau protein and interactions with microtubules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Recognition of the minimal epitope of monoclonal antibody Tau‐1 depends upon the presence of a phosphate group but not its location

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Association of tau protein with microtubules in living cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.10.5589

21 January 2018

Identifiers

10.1074/JBC.271.10.5589

1 reference

Europe PubMed Central

PubMed publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 September 2017

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