(Q41008542)

25 September 2017

title

The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication (English)

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25 September 2017

L R Barrows

1

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25 September 2017

J A Holden

series ordinal

2

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25 September 2017

M Anderson

series ordinal

3

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25 September 2017

P D'Arpa

series ordinal

4

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25 September 2017

language of work or name

English

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publication date

1 August 1998

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25 September 2017

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25 September 2017

volume

408

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25 September 2017

issue

2

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25 September 2017

page(s)

103-110

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Preclinical and phase I trials of topoisomerase I inhibitors

25 September 2017

cites work

1 reference

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7 January 2021

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7 January 2021

Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme

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7 January 2021

cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment

1 reference

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7 January 2021

Eukaryotic DNA polymerases alpha and delta: conserved properties and interactions, from yeast to mammalian cells

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7 January 2021

A screening method for isolating DNA repair-deficient mutants of CHO cells

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7 January 2021

A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange

1 reference

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7 January 2021

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

1 reference

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7 January 2021

Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2898%2900022-6

7 January 2021

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2898%2900022-6

7 January 2021

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

1 reference

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7 January 2021

DNA joining in mammalian cells

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7 January 2021

The distribution of DNA topoisomerase II isoforms in differentiated adult mouse tissues

1 reference

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7 January 2021

Transfectant CHO cells expressing O6-alkylguanine-DNA-alkyltransferase display increased resistance to DNA damage other than O6-guanine alkylation

1 reference

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7 January 2021

Detection of anti-topoisomerase I antibodies using a full length human topoisomerase I recombinant protein purified from a baculovirus expression system

1 reference

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7 January 2021

Characterization of revertants of the CHO EM9 mutant arising during DNA transfection

1 reference

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7 January 2021

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2898%2900022-6

7 January 2021

Importance of replication fork progression for the induction of chromosome damage and SCE by inhibitors of DNA topoisomerases

1 reference

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7 January 2021

The human cell multiprotein DNA replication complex (MRC): the effect of camptothecin on its ability to support in vitro DNA synthesis

1 reference

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7 January 2021

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

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7 January 2021

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

1 reference

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7 January 2021

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

1 reference

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7 January 2021

Higher G2 sensitivity to the induction of chromosomal damage in the CHO mutant EM9 than in its parental line AA8 by camptothecin, an inhibitor of DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0921-8777%2898%2900022-6

7 January 2021

10.1016/S0921-8777(98)00022-6

Identifiers

DOI

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25 September 2017

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