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Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.
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Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
title
Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
apoptotic process
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author
Michael Khan
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
Stella Pelengaris
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Gerard I Evan
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
language of work or name
English
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publication date
1 May 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
109
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
321-334
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
cites work
Inducible and reversible beta-cell autoimmunity and hyperplasia in transgenic mice expressing a conditional oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptotic cell death induced by c-myc is inhibited by bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
beta-cell turnover: its assessment and implications
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Angiogenesis is an early event in the generation of myc-induced lymphomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for oncogenic Ras in tumour maintenance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deconstructing myc.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A matter of life and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferation, cell cycle and apoptosis in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in fibroblasts by c-myc protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative interaction between c-myc and bcl-2 proto-oncogenes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversible tumorigenesis by MYC in hematopoietic lineages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neuroblastoma cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Hallmarks of Cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-induced expression of the fibroblast growth factor-binding protein is transcriptionally repressed through a non-canonical E-box element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Twist is a potential oncogene that inhibits apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A causal role for E-cadherin in the transition from adenoma to carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cadherins in cancer: implications for invasion and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900738-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(02)00738-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PubMed publication ID
12015982
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12015982
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12015982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
ResearchGate publication ID
11355675
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