(Q40655044)

English

Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene

scientific article published on April 15, 2003

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Europe PubMed Central

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22 September 2017

Induction of osteoclast differentiation by Runx2 through receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin regulation and partial rescue of osteoclastogenesis in Runx2-/- mice by RANKL transgene (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene (English)

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

neoplasm protein

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697767

24 December 2023

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Hisataka Yasuda

12

object named as

Hisataka Yasuda

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697767

24 December 2023

author name string

Hirayuki Enomoto

1

1 reference

Europe PubMed Central

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22 September 2017

Satoko Shiojiri

2

1 reference

Europe PubMed Central

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22 September 2017

Kazuto Hoshi

3

1 reference

Europe PubMed Central

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22 September 2017

Tatsuya Furuichi

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Ryo Fukuyama

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Naoko Kanatani

7

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Reiko Nakamura

8

1 reference

Europe PubMed Central

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22 September 2017

Atsuko Mizuno

9

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Akira Zanma

10

1 reference

Europe PubMed Central

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22 September 2017

Kazuki Yano

11

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Kanji Higashio

13

1 reference

Europe PubMed Central

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22 September 2017

Kenji Takada

14

1 reference

Europe PubMed Central

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22 September 2017

Toshihisa Komori

15

1 reference

Europe PubMed Central

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22 September 2017

Carolina A. Yoshida

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697767

24 December 2023

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publication date

15 April 2003

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Europe PubMed Central

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22 September 2017

number of pages

7

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full work available at URL

http://www.jbc.org/article/S0021925820862103/pdf

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697767

24 December 2023

https://api.elsevier.com/content/article/PII:S0021925820862103?httpAccept=text/xml

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

https://api.elsevier.com/content/article/PII:S0021925820862103?httpAccept=text/plain

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

https://syndication.highwire.org/content/doi/10.1074/jbc.M302457200

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

26

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

23971-23977

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Modulation of osteoclast differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesisin Vitro1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

RANK is essential for osteoclast and lymph node development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Core-binding factor beta interacts with Runx2 and is required for skeletal development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Cbfbeta interacts with Runx2 and has a critical role in bone development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

The core-binding factor beta subunit is required for bone formation and hematopoietic maturation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Maturational disturbance of chondrocytes in Cbfa1-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Regulation of chondrocyte differentiation by Cbfa1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Cbfa1 is a positive regulatory factor in chondrocyte maturation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Gene replacement of the p53 gene with the lacZ gene in mouse embryonic stem cells and mice by using two steps of homologous recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Multilineage differentiation of Cbfa1-deficient calvarial cells in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Developmental and liver-specific expression directed by the serum amyloid P component promoter in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Runt domain factor (Runx)-dependent effects on CCAAT/ enhancer-binding protein delta expression and activity in osteoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Cbfa1 isoforms exert functional differences in osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Localization of RANKL (receptor activator of NF kappa B ligand) mRNA and protein in skeletal and extraskeletal tissues.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Relative role of CSF-1, MCP-1/JE, and RANTES in macrophage recruitment during successful pregnancy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302457200

21 January 2018

Endocrine Reviews

2

13

66

author name string

Suda

publication date

1992

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Cbfa1 in bone development

19

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Runx2, a multifunctional transcription factor in skeletal development

30

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF)

31

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Impaired vascular invasion of Cbfa1-deficient cartilage engrafted in the spleen

36

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

39

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

20 Role of 1α,25-dihydroxyvitamin D3 in osteoclast differentiation and function

40

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Morphological characterization of skeletal cells in Cbfa1-deficient mice

45

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Endocrine Reviews

54

21

115

author name string

Manolagas

publication date

2000

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Role of colony-stimulating factor-1 in bone metabolism

59

1 reference

10.1074/JBC.M302457200

https://api.crossref.org/works/10.1074/JBC.M302457200

24 December 2023

Identifiers

10.1074/JBC.M302457200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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