(Q39029239)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

12

1 reference

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6 March 2020

author name string

Changjie Wu

1

1 reference

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6 March 2020

Sunquan Qiu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Liting Lu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Jiawei Zou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Wen-feng Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Ouchen Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Haina Zhao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Hongxiao Wang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Jiajia Tang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Lin Chen

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Tao Xu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Wanqin Liao

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Guangbin Luo

14

1 reference

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6 March 2020

Xincheng Lu

15

1 reference

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6 March 2020

language of work or name

English

0 references

publication date

1 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24476626%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

published in

Nature Communications

1 reference

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6 March 2020

volume

5

1 reference

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6 March 2020

page(s)

3149

1 reference

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6 March 2020

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R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

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A WNT/β-Catenin Signaling Activator, R-spondin, Plays Positive Regulatory Roles during Skeletal Myogenesis

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Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb

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A new common integration site, Int7, for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin-like sequences

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Rspo2/Int7 regulates invasiveness and tumorigenic properties of mammary epithelial cells.

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A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

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Recurrent R-spondin fusions in colon cancer

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R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

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Epigenetic regulation and colorectal cancer

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LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

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LGR5 Is a Negative Regulator of Tumourigenicity, Antagonizes Wnt Signalling and Regulates Cell Adhesion in Colorectal Cancer Cell Lines

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21 January 2018

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R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Corneal endothelial cell fate is maintained by LGR5 through the regulation of hedgehog and Wnt pathway

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