(Q38699912)

5 September 2017

title

The targeting effect of Hm2E8b-NCTD-liposomes on B-lineage leukaemia stem cells is associated with the HLF-SLUG axis (English)

1 reference

5 September 2017

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Jingying Zhang

1

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5 September 2017

Diying Shen

2

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5 September 2017

Min Jia

3

1 reference

5 September 2017

Haizhao Zhao

4

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5 September 2017

Yongmin Tang

5

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5 September 2017

publication date

19 June 2017

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Journal of Drug Targeting

5 September 2017

published in

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5 September 2017

page(s)

1-11

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

5 September 2017

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Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).

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Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior

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A stem cell molecular signature

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A PAR domain transcription factor is involved in the expression from a hematopoietic-specific promoter for the human LMO2 gene

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Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

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The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development

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Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19.

21 January 2018

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E2A-HLF usurps control of evolutionarily conserved survival pathways

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Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.

21 January 2018

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Bmi-1 Regulation of INK4A-ARF Is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

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Cantharidin analogues: synthesis and evaluation of growth inhibition in a panel of selected tumour cell lines

21 January 2018

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The protein phosphatases involved in cellular regulation. 6. Measurement of type-1 and type-2 protein phosphatases in extracts of mammalian tissues; an assessment of their physiological roles

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Norcantharidin preferentially induces apoptosis in human leukemic Jurkat cells without affecting viability of normal blood mononuclear cells.

21 January 2018

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Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

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Analysis of gene expression profiles in human HL-60 cell exposed to cantharidin using cDNA microarray

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E4BP4 expression is regulated by the t(17;19)-associated oncoprotein E2A-HLF in pro-B cells

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Targeting of the B-lineage leukemia stem cells and their progeny with norcantharidin encapsulated liposomes modified with a novel CD19 monoclonal antibody 2E8 in vitro

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Successful construction and massive expression of a novel Anti-CD19 human-mouse chimeric antibody Hm2E8b

21 January 2018

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Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes

21 January 2018

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Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates

21 January 2018

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Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel

21 January 2018

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Surface-modified liposomes: assessment and characterization for increased stability and prolonged blood circulation

21 January 2018

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Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells

21 January 2018

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STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPalpha.

21 January 2018

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Transcriptional repression by a novel member of the bZIP family of transcription factors

21 January 2018

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https://api.crossref.org/works/10.1080%2F1061186X.2017.1339193

Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain

21 January 2018

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https://api.crossref.org/works/10.1080%2F1061186X.2017.1339193

Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1061186X.2017.1339193

Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1061186X.2017.1339193

Oncogenic Transcription Factors in the Human Acute Leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1061186X.2017.1339193

10.1080/1061186X.2017.1339193

21 January 2018

Identifiers

DOI

1 reference

5 September 2017

1 reference