(Q38162112)

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Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides

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Europe PubMed Central

PubMed publication ID

30 August 2017

Incorporation of post-translational modified amino acids as an approach to increase both chemical and biological diversity of conotoxins and conopeptides (English)

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Europe PubMed Central

PubMed publication ID

30 August 2017

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based on heuristic

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Chino C Cabalteja

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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Michael J Espiritu

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Christopher K Sugai

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jon-Paul Bingham

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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13 November 2013

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Europe PubMed Central

PubMed publication ID

30 August 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

46

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

125-151

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24221351%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Conorfamide-Sr2, a gamma-carboxyglutamate-containing FMRFamide-related peptide from the venom of Conus spurius with activity in mice and mollusks

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Synthesis and characterization of delta-atracotoxin-Ar1a, the lethal neurotoxin from venom of the Sydney funnel-web spider (Atrax robustus).

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Conotoxins as research tools and drug leads

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

gamma -Glutamyl carboxylation: An extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

A conserved motif within the vitamin K-dependent carboxylase gene is widely distributed across animal phyla

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Constrained de novo sequencing of conotoxins.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Optimizing the connectivity in disulfide-rich peptides: alpha-conotoxin SII as a case study

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Drugs from slugs--past, present and future perspectives of omega-conotoxin research

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Drugs from slugs. Part II--conopeptide bioengineering

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Conotoxins and the posttranslational modification of secreted gene products

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Efficient oxidative folding of conotoxins and the radiation of venomous cone snails

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Cone snail milked venom dynamics--a quantitative study of Conus purpurascens

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

A novel post-translational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

An O-glycosylated neuroexcitatory conus peptide

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Contulakin-G, an O-glycosylated invertebrate neurotensin

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Post-translationally modified neuropeptides from Conus venoms

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Enzymatic glycosylation of contulakin-G, a glycopeptide isolated from Conus venom, with a mammalian ppGalNAc-transferase

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Chemical modification of conotoxins to improve stability and activity

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Expression and characterization of recombinant vitamin K-dependent gamma-glutamyl carboxylase from an invertebrate, Conus textile

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

1H NMR conformational study of sulfated and non-sulfated cholecystokinin fragment CCK27-33: influence of the sulfate group on the peptide folding

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Role of disulfide bridges in the folding, structure and biological activity of omega-conotoxin GVIA.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Rapid gas chromatographic separation of amino acid enantiomers with a novel chiral stationary phase

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Glycosylation of conotoxins

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Prolyl 4-hydroxylase

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Disulfide structures of highly bridged peptides: a new strategy for analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Chemical syntheses and biological activities of lactam analogues of alpha-conotoxin SI.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Identification and characterization of a novel kaempferol sulfotransferase from Arabidopsis thaliana

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Structure of the O-glycosylated conopeptide CcTx from Conus consors venom

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Bromocontryphan: post-translational bromination of tryptophan

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is alpha-D-Gal-(1-->3)-alpha-D-GalNAc

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Protein Folding Determinants: Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Conotoxin truncation as a post-translational modification to increase the pharmacological diversity within the milked venom of Conus magus

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Design of New α-Conotoxins: From Computer Modeling to Synthesis of Potent Cholinergic Compounds

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Tyrosine sulfation: a modulator of extracellular protein-protein interactions

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Distinct Disulfide Isomers of μ-Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium Channels

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

D-amino acids in animal peptides

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

A new approach for detecting C-terminal amidation of proteins and peptides by mass spectrometry in conjunction with chemical derivatization

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Novel alpha D-conopeptides and their precursors identified by cDNA cloning define the D-conotoxin superfamily

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Single-residue alteration in alpha-conotoxin PnIA switches its nAChR subtype selectivity

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Identification and characterization of zebrafish SULT1 ST9, SULT3 ST4, and SULT3 ST5.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

De novo sequencing and disulfide mapping of a bromotryptophan-containing conotoxin by Fourier transform ion cyclotron resonance mass spectrometry.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Mass spectrometric-based revision of the structure of a cysteine-rich peptide toxin with gamma-carboxyglutamic acid, TxVIIA, from the sea snail, Conus textile

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Identification of tyrosine sulfation in extracellular leucine-rich repeat proteins using mass spectrometry

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Polypeptide chains containing D-gamma-hydroxyvaline

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Characterization of a gamma-carboxyglutamic acid-containing protein from bone

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Folding of omega-conotoxins. 2. Influence of precursor sequences and protein disulfide isomerase

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

TxXIIIA, an atypical homodimeric conotoxin found in the Conus textile venom.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Synthesis and characterization of leiurotoxin I analogs lacking one disulfide bridge: evidence that disulfide pairing 3-21 is not required for full toxin activity

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

The A-superfamily of conotoxins: structural and functional divergence

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Discrimination of isobaric leucine and isoleucine residues and analysis of post-translational modifications in peptides by MALDI in-source decay mass spectrometry combined with collisional cooling

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Vitamin K Dependent Modifications of Glutamic Acid Residues in Prothrombin

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Conus venoms: a rich source of novel ion channel-targeted peptides

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Rapid mass spectral identification of contryphans. Detection of characteristic peptide ions by fragmentation of intact disulfide-bonded peptides in crude venom.

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

The T-superfamily of conotoxins

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Molecular cloning, expression and characterization of protein disulfide isomerase from Conus marmoreus

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Cloning and Expression of the cDNA for Human γ-glutamyl Carboxylase

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Novel conopeptides in a form of disulfide-crosslinked dimer

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels

1 reference

https://api.crossref.org/works/10.1007%2FS00726-013-1606-X

21 January 2018

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