(Q38050689)

27 August 2017

title

The genetic and epigenetic basis of type 2 diabetes and obesity (English)

1 reference

27 August 2017

0 references

0 references

A W Drong

1

1 reference

27 August 2017

C M Lindgren

series ordinal

2

1 reference

27 August 2017

M I McCarthy

series ordinal

3

1 reference

27 August 2017

language of work or name

English

0 references

publication date

10 October 2012

1 reference

Clinical Pharmacology & Therapeutics

27 August 2017

published in

1 reference

27 August 2017

volume

92

1 reference

27 August 2017

issue

6

1 reference

27 August 2017

page(s)

707-715

1 reference

IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Mortality attributable to diabetes: estimates for the year 2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Health and economic burden of the projected obesity trends in the USA and the UK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Parental transmission of type 2 diabetes: the Framingham Offspring Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance--a population-based twin study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Predicting Obesity in Young Adulthood from Childhood and Parental Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The Body-Mass Index of Twins Who Have Been Reared Apart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genomics, Type 2 Diabetes, and Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Diagnosis and management of maturity onset diabetes of the young (MODY).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

A transcription factor regulatory circuit in differentiated pancreatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The future of genetic studies of complex human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Meta-analysis identifies common variants associated with body mass index in east Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

A map of open chromatin in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The International HapMap Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Variants in MTNR1B influence fasting glucose levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Common variants near MC4R are associated with fat mass, weight and risk of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome-wide association studies provide new insights into type 2 diabetes aetiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The role of ATM in response to metformin treatment and activation of AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

A methodological perspective on genetic risk prediction studies in type 2 diabetes: recommendations for future research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Finding the missing heritability of complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Clan genomics and the complex architecture of human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The mystery of missing heritability: Genetic interactions create phantom heritability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Review: chromatin structural features and targets that regulate transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Epigenetics: molecular mechanisms and implications for disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Persistent epigenetic differences associated with prenatal exposure to famine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Minireview: Epigenetic programming of diabetes and obesity: animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Epigenetic inheritance at the agouti locus in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome-wide DNA methylation profiling using Infinium® assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Epigenome-wide association studies for common human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Heritability in the genomics era — concepts and misconceptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Metastable epialleles in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Type 2 diabetes risk alleles are associated with reduced size at birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Prevalence of Mutations and Functional Analyses of Melanocortin 4 Receptor Variants Identified among 750 Men with Juvenile-Onset Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

What makes a good genetic association study?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

The response to long-term overfeeding in identical twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.149

inferred from DOI database lookup

7 January 2021

based on heuristic

Congenital Susceptibility to NIDDM: Role of Intrauterine Environment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23047653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A twin study of human obesity.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23047653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CLPT.2012.149

1 reference

27 August 2017

1 reference