(Q38031282)

27 August 2017

title

The sweet side of tumor immunotherapy (English)

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27 August 2017

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Teresa Freire

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27 August 2017

Eduardo Osinaga

series ordinal

2

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27 August 2017

publication date

1 July 2012

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27 August 2017

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27 August 2017

volume

4

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27 August 2017

issue

7

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27 August 2017

page(s)

719-734

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Glycosylation defining cancer cell motility and invasiveness

27 August 2017

cites work

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Signaling in innate immunity and inflammation

21 January 2018

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Post-translationally modified T cell epitopes: immune recognition and immunotherapy

21 January 2018

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Cell surface glycan–lectin interactions in tumor metastasis

21 January 2018

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Carbohydrate antigens: synthesis aspects and immunological applications in cancer

21 January 2018

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Suppression of tumor growth and metastasis in Mgat5-deficient mice

21 January 2018

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Genes that mediate breast cancer metastasis to the brain

21 January 2018

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pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen.

21 January 2018

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N-Glycans in cancer progression

21 January 2018

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Axis of evil: molecular mechanisms of cancer metastasis

21 January 2018

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Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients

21 January 2018

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Carbohydrate signals in metastasis and prognosis of human carcinomas

21 January 2018

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The sweet and sour of cancer: glycans as novel therapeutic targets

21 January 2018

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Targeting the GD3 acetylation pathway selectively induces apoptosis in glioblastoma.

21 January 2018

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Glycan changes: cancer metastasis and anti-cancer vaccines

21 January 2018

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Cancer immunoediting: from immunosurveillance to tumor escape

21 January 2018

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Natural Innate and Adaptive Immunity to Cancer

21 January 2018

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

21 January 2018

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Immunosurveillance in human non-viral cancers

21 January 2018

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Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication

21 January 2018

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A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

21 January 2018

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Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells.

21 January 2018

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Overproduction of PGE2 in peripheral blood monocytes of gastrointestinal cancer patients with mucins in their bloodstream

21 January 2018

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Different progression of tumor xenografts between mucin-producing and mucin-non-producing mammary adenocarcinoma-bearing mice

21 January 2018

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Selectin ligands: will the real ones please stand up?

21 January 2018

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Consequences of the expression of sialylated antigens in breast cancer

21 January 2018

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Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.

21 January 2018

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Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion.

21 January 2018

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Anti-Thomsen-Friedenreich-Ag (anti-TF-Ag) potential for cancer therapy.

21 January 2018

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Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

21 January 2018

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Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs

21 January 2018

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GM2 expression in renal cell carcinoma: potential role in tumor-induced T-cell dysfunction

21 January 2018

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Tumor antigen epitopes interpreted by the immune system as self or abnormal-self differentially affect cancer vaccine responses

21 January 2018

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Cross-Talk between Tumor and Myeloid Cells: How to Tip the Balance in Favor of Antitumor Immunity

21 January 2018

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Tn Glycosylation of the MUC6 Protein Modulates Its Immunogenicity and Promotes the Induction of Th17-biased T Cell Responses

21 January 2018

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Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes

21 January 2018

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Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen-induced arthritis.

21 January 2018

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O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells

21 January 2018

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Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells

21 January 2018

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

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Carbohydrates and antigen recognition by T cells.

21 January 2018

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Post-translational modifications of proteins: implications for aging, antigen recognition, and autoimmunity

21 January 2018

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Repertoire development and the control of cytotoxic/effector function in human gammadelta T cells

21 January 2018

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Antigen recognition by CD1d-restricted NKT T cell receptors.

21 January 2018

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Lipid and glycolipid antigens of CD1d-restricted natural killer T cells

21 January 2018

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Harnessing human CD1d restricted T cells for tumor immunity: progress and challenges

21 January 2018

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The danger model: a renewed sense of self

21 January 2018

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Protein-glycan interactions in the control of innate and adaptive immune responses

21 January 2018

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Bridging innate and adaptive antitumor immunity targeting glycans.

21 January 2018

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Siglecs in the immune system

21 January 2018

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Siglecs as targets for therapy in immune-cell-mediated disease

21 January 2018

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Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9

21 January 2018

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MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion

21 January 2018

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Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes

21 January 2018

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Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant

21 January 2018

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Ligand recognition by antigen-presenting cell C-type lectin receptors

21 January 2018

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Signaling by myeloid C-type lectin receptors in immunity and homeostasis

21 January 2018

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The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma

21 January 2018

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Sweet preferences of MGL: carbohydrate specificity and function

21 January 2018

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GD2 oligosaccharide: target for cytotoxic T lymphocytes

21 January 2018

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Multiple roles for CD4+ T cells in anti-tumor immune responses

21 January 2018

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T cell recognition of Tn-glycosylated peptide antigens

21 January 2018

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Complex carbohydrates are not removed during processing of glycoproteins by dendritic cells: processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cells

21 January 2018

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Designer glycopeptides for cytotoxic T cell-based elimination of carcinomas

21 January 2018

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A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor

21 January 2018

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Phase 1 trial of immunological adjuvant QS-21 with a GM2 ganglioside-keyhole limpet haemocyanin conjugate vaccine in patients with malignant melanoma

21 January 2018

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Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes

21 January 2018

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A mutant chaperone converts a wild-type protein into a tumor-specific antigen

21 January 2018

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Natural anti-Gal antibody as a universal augmenter of autologous tumor vaccine immunogenicity

21 January 2018

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Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity

21 January 2018

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Antibody-dependent cell cytotoxicity synapses form in mice during tumor-specific antibody immunotherapy

21 January 2018

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Using monoclonal antibodies to stimulate antitumor cellular immunity

21 January 2018

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Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts

21 January 2018

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Specificity analysis of blood group Lewis-y (Le(y)) antibodies generatedagainst synthetic and natural Le(y) determinants

21 January 2018

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Human Monoclonal Antibodies to Sialyl-Lewisa (CA19.9) with Potent CDC, ADCC, and Antitumor Activity

21 January 2018

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Immunology in the clinic review series; focus on cancer: glycolipids as targets for tumour immunotherapy

21 January 2018

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Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface

21 January 2018

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Targeting tumours with genetically enhanced T lymphocytes

21 January 2018

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Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy

21 January 2018

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Targeting of G(D2)-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes

21 January 2018

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Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors

21 January 2018

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Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells

21 January 2018

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Anti-GD3 chimeric sFv-CD28/T-cell receptor zeta designer T cells for treatment of metastatic melanoma and other neuroectodermal tumors

21 January 2018

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Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice

21 January 2018

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Retargeting of human T cells to tumor-associated MUC1: the evolution of a chimeric antigen receptor

21 January 2018

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CAR mechanics: driving T cells into the MUC of cancer

21 January 2018

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Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4.

21 January 2018

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Chimeric antigen receptor-engineered T cells for immunotherapy of cancer

21 January 2018

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Ganglioside conjugate vaccines. Immunotherapy against tumors of neuroectodermal origin

21 January 2018

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Comparison of antigen constructs and carrier molecules for augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn.

21 January 2018

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Immunogenicity of synthetic conjugates of Lewis y oligosaccharide with proteins in mice: towards the design of anticancer vaccines

21 January 2018

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Recent development in carbohydrate-based cancer vaccines

21 January 2018

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Induction of a melanoma-specific antibody response by a monovalent, but not a divalent, synthetic GM2 neoglycopeptide

21 January 2018

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Chemoselective assembly and immunological evaluation of multiepitopic glycoconjugates bearing clustered Tn antigen as synthetic anticancer vaccines

21 January 2018

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Toward optimized carbohydrate-based anticancer vaccines: epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewis(y) conjugates in mice

21 January 2018

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Anti-tumor immunity provided by a synthetic multiple antigenic glycopeptide displaying a tri-Tn glycotope

21 January 2018

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A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates

21 January 2018

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Synthetic carbohydrate vaccines: synthesis and immunogenicity of Tn antigen conjugates.

21 January 2018

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Sequential immunization of melanoma patients with GD3 ganglioside vaccine and anti-idiotypic monoclonal antibody that mimics GD3 ganglioside

21 January 2018

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Carbohydrate vaccines as immunotherapy for cancer

21 January 2018

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What makes MUC1 a tumor antigen?

21 January 2018

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Sequence-variant repeats of MUC1 show higher conformational flexibility, are less densely O-glycosylated and induce differential B lymphocyte responses

21 January 2018

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Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice

21 January 2018

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From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine

21 January 2018

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Mucin-type O-glycosylation and its potential use in drug and vaccine development

21 January 2018

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The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters

21 January 2018

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Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines

21 January 2018

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Efficient metabolic engineering of GM3 on tumor cells by N-phenylacetyl-D-mannosamine

21 January 2018

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Differential antigen processing by dendritic cell subsets in vivo

21 January 2018

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Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells

21 January 2018

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Signalling through C-type lectin receptors: shaping immune responses

21 January 2018

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Design of neo-glycoconjugates that target the mannose receptor and enhance TLR-independent cross-presentation and Th1 polarization

21 January 2018

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Mannan mucin-1 peptide immunization: influence of cyclophosphamide and the route of injection

21 January 2018

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Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy

21 January 2018

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T/Tn antigen vaccine is effective and safe in preventing recurrence of advanced human breast carcinoma

21 January 2018

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Cancer vaccines: between the idea and the reality

21 January 2018

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Alterations in dendritic cell function in aged mice: potential implications for immunotherapy design.

21 January 2018

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Analysis of the fine specificity of Tn-binding proteins using synthetic glycopeptide epitopes and a biosensor based on surface plasmon resonance spectroscopy

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/IMT.12.58

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27 August 2017

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