(Q38004927)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Regulation of Parkin E3 ubiquitin ligase activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

19 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

69

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

3053-3067

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

Update on the genetics of Parkinson's disease

29 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Genetic Analysis of Pathways to Parkinson Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Autosomal recessive parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Rare genetic mutations shed light on the pathogenesis of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The role of parkin in familial and sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkinson's disease and cancer: two wars, one front

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Characterizing the cancer genome in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The emerging complexity of protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The emerging role of linear ubiquitination in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Nonproteolytic functions of ubiquitin in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

A ubiquitin mutant with specific defects in DNA repair and multiubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The diversity of ubiquitin recognition: hot spots and varied specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

SEPT5_v2 is a parkin-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin ubiquitinates and promotes the degradation of RanBP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin Mono-ubiquitinates Bcl-2 and Regulates Autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Loss of locus coeruleus neurons and reduced startle in parkin null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

21 January 2018

Mechanisms of mitophagy

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Autoregulation of Parkin activity through its ubiquitin-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Pathogenic mutations inactivate parkin by distinct mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

RING finger 1 mutations in Parkin produce altered localization of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mitophagy and Parkinson's disease: the PINK1-parkin link.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PINK1 function in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Time-course gait analysis of hemiparkinsonian rats following 6-hydroxydopamine lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Structural regulation of cullin-RING ubiquitin ligase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin occurs in a stable, non-covalent, approximately 110-kDa complex in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

14-3-3eta is a novel regulator of parkin ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Functional modulation of parkin through physical interaction with SUMO-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Policing Parkin with a UblD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Building ubiquitin chains: E2 enzymes at work

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Breaking the chains: structure and function of the deubiquitinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Ataxin-3 deubiquitination is coupled to Parkin ubiquitination via E2 ubiquitin-conjugating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin interacts with Klokin1 for mitochondrial import and maintenance of membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin interacts with Ambra1 to induce mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

DNA damage induces nuclear translocation of parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin, A Top Level Manager in the Cells Sanitation Department

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Posttranslational modifications as versatile regulators of parkin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfunction in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Ubiquitin ligase complexes: from substrate selectivity to conjugational specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Neddylation positively regulates the ubiquitin E3 ligase activity of parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Identification of far upstream element-binding protein-1 as an authentic Parkin substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Of Parkin and Parkinson's: light and dark sides of a multifaceted E3 ubiquitin–protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0978-5

Parkin expression in the adult mouse brain

21 January 2018

1 reference

12 December 2020

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

1 reference

12 December 2020

Toward understanding Machado-Joseph disease

1 reference

12 December 2020

Mutant ataxin-3 promotes the autophagic degradation of parkin

1 reference

12 December 2020

Ubiquitin signalling in DNA replication and repair

1 reference

12 December 2020

Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation

1 reference

12 December 2020

Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries

1 reference

12 December 2020

Regulation of parkin and PINK1 by neddylation

1 reference

12 December 2020

Combined kinase inhibition modulates parkin inactivation.

1 reference

12 December 2020

Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin

1 reference

12 December 2020

10.1007/S00018-012-0978-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22527713%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference