(Q37986997)

26 August 2017

title

Neuroprotective mechanisms of hypothermia in brain ischaemia (English)

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26 August 2017

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Midori A Yenari

1

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26 August 2017

Hyung Soo Han

series ordinal

2

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26 August 2017

language of work or name

English

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publication date

22 February 2012

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Nature Reviews Neuroscience

26 August 2017

published in

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26 August 2017

volume

13

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26 August 2017

issue

4

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26 August 2017

page(s)

267-278

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Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

26 August 2017

cites work

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31 March 2020

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31 March 2020

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Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats

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Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia

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Hypothermia enhances heat-shock protein 70 production in ischemic brains

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Characterization of hypothermia-induced cellular stress response in mouse tissues

31 March 2020

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Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection

31 March 2020

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The effect of hypothermia on induction of heat shock protein (HSP)-72 in ischemic brain

31 March 2020

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Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade.

31 March 2020

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The MicroRNAs and Stroke: No Need to be Coded to be Counted

31 March 2020

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Therapeutic hypothermia alters microRNA responses to traumatic brain injury in rats

31 March 2020

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Mitochondria and apoptosis

31 March 2020

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31 March 2020

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Therapeutic hypothermia: neuroprotective mechanisms

31 March 2020

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Protein kinase C delta mediates cerebral reperfusion injury in vivo.

31 March 2020

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Protein kinase C delta cleavage initiates an aberrant signal transduction pathway after cardiac arrest and oxygen glucose deprivation

31 March 2020

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The protective effect of early hypothermia on PTEN phosphorylation correlates with free radical inhibition in rat stroke

31 March 2020

1 reference

Epsilon PKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model

31 March 2020

1 reference

Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

31 March 2020

1 reference

FasL shedding is reduced by hypothermia in experimental stroke

31 March 2020

1 reference

Multiple roles for MMPs and TIMPs in cerebral ischemia

31 March 2020

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The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

31 March 2020

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Mild to moderate hypothermia prevents microvascular basal lamina antigen loss in experimental focal cerebral ischemia

31 March 2020

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Reduction in levels of matrix metalloproteinases and increased expression of tissue inhibitor of metalloproteinase-2 in response to mild hypothermia therapy in experimental stroke.

31 March 2020

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Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats

31 March 2020

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Topographically graded postischemic presence of metalloproteinases is inhibited by hypothermia

31 March 2020

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Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke

31 March 2020

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Molecular characterization of mitochondrial apoptosis-inducing factor

31 March 2020

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Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion

31 March 2020

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PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

31 March 2020

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Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrest

31 March 2020

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Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation

31 March 2020

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Regional changes in glial cell line-derived neurotrophic factor after cardiac arrest and hypothermia in rats

31 March 2020

1 reference

The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat.

31 March 2020

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Hypothermia differentially increases extracellular signal-regulated kinase and stress-activated protein kinase/c-Jun terminal kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest

31 March 2020

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Hypothermia and ERK activation after cardiac arrest

31 March 2020

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Hypothermia enhances bcl-2 expression and protects against oxidative stress-induced cell death in Chinese hamster ovary cells

31 March 2020

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Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia

31 March 2020

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Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats.

31 March 2020

1 reference

The inflammatory response in stroke

31 March 2020

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The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia

31 March 2020

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Whole Body Hypothermia and Oxidative Stress in Babies With Hypoxic-Ischemic Brain Injury

31 March 2020

1 reference

Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation.

31 March 2020

1 reference

Mild hypothermia inhibits inflammation after experimental stroke and brain inflammation

31 March 2020

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Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation

31 March 2020

1 reference

Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia

31 March 2020

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IL-10 production is reduced by hypothermia but augmented by hyperthermia in rat microglia

31 March 2020

1 reference

The effect of therapeutic hypothermia on the expression of inflammatory response genes following moderate traumatic brain injury in the rat

31 March 2020

1 reference

Influence of hypothermia on post-ischemic inflammation: role of nuclear factor kappa B (NFkappaB)

31 March 2020

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Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke.

31 March 2020

1 reference

Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia.

31 March 2020

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Roles of nuclear factor kappaB in neuronal survival and plasticity

31 March 2020

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Hypothermia suppresses inflammation via ERK signaling pathway in stimulated microglial cells

31 March 2020

1 reference

The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia.

31 March 2020

1 reference

Effect of delayed mild brain hypothermia on edema formation after intracerebral hemorrhage in rats.

31 March 2020

1 reference

The influence of hypothermia on outcome after intracerebral hemorrhage in rats.

31 March 2020

1 reference

Combinational Therapy Using Hypothermia and the Immunophilin Ligand FK506 to Target Altered Pial Arteriolar Reactivity, Axonal Damage, and Blood–Brain Barrier Dysfunction after Traumatic Brain Injury in Rat

31 March 2020

1 reference

A two-hour window for hypothermic modulation of early events that impact delayed opening of the rat blood-brain barrier after ischemia

31 March 2020

1 reference

Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: effects on BBB breakdown and MMP expression in the acute and subacute phase

31 March 2020

1 reference

Post-ischemic hypothermia attenuates loss of the vascular basement membrane proteins, agrin and SPARC, and the blood-brain barrier disruption after global cerebral ischemia

31 March 2020

1 reference

The effect of moderate hypothermia in acute ischemic stroke on pericyte migration: an ultrastructural study

31 March 2020

1 reference

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

31 March 2020

1 reference

Cerebral cortical aquaporin-4 expression in brain edema following cardiac arrest in rats

31 March 2020

1 reference

Effect of therapeutic moderate hypothermia on multi-drug resistance protein 1-mediated transepithelial transport of drugs

31 March 2020

1 reference

Treatment of intracerebral hemorrhage in rats with 12 h, 3 days and 6 days of selective brain hypothermia

31 March 2020

1 reference

Hypothermia reduces perihemorrhagic edema after intracerebral hemorrhage

31 March 2020

1 reference

Coagulopathy by hypothermia and acidosis: mechanisms of thrombin generation and fibrinogen availability

31 March 2020

1 reference

The effects of hypothermia on fibrinogen metabolism and coagulation function in swine

31 March 2020

1 reference

Forebrain neurogenesis after focal Ischemic and traumatic brain injury

31 March 2020

1 reference

Angiogenesis, Neurogenesis and Neuroplasticity in Ischemic Stroke

31 March 2020

1 reference

Neurogenesis in the aged and neurodegenerative brain

31 March 2020

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Decline in adult neurogenesis during aging follows a topographic pattern in the mouse hippocampus

31 March 2020

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A decrease of cell proliferation by hypothermia in the hippocampus of the neonatal rat.

31 March 2020

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Post-ischemic hypothermia promotes generation of neural cells and reduces apoptosis by Bcl-2 in the striatum of neonatal rat brain

31 March 2020

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Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein

31 March 2020

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Therapeutic hypothermia influences cell genesis and survival in the rat hippocampus following global ischemia.

31 March 2020

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Mild hypothermia has no long-term impact on postischemic neurogenesis in rats

31 March 2020

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Oligodendrocyte vulnerability following traumatic brain injury in rats

31 March 2020

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OLIGODENDROCYTE VULNERABILITY FOLLOWING TRAUMATIC BRAIN INJURY IN RATS: EFFECT OF MODERATE HYPOTHERMIA.

31 March 2020

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Hypothermia-induced increase of oligodendrocyte precursor cells: Possible involvement of plasmalemmal voltage-dependent anion channel 1

31 March 2020

1 reference

The effect of cerebral hypothermia on white and grey matter injury induced by severe hypoxia in preterm fetal sheep

31 March 2020

1 reference

Stem cells in stroke repair: current success and future prospects

31 March 2020

1 reference

Focal cerebral ischemia induces a multilineage cytogenic response from adult subventricular zone that is predominantly gliogenic

31 March 2020

1 reference

The Unusual Response of Serotonergic Neurons after CNS Injury: Lack of Axonal Dieback and Enhanced Sprouting within the Inhibitory Environment of the Glial Scar

31 March 2020

1 reference

Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning

31 March 2020

1 reference

Effect of mild hypothermia on angiogenesis in rats with focal cerebral ischemia

31 March 2020

1 reference

Body Cooling Ameliorating Spinal Cord Injury May Be Neurogenesis-, Anti-inflammation- and Angiogenesis-Associated in Rats

31 March 2020

1 reference

Brain Cooling-Stimulated Angiogenesis and Neurogenesis Attenuated Traumatic Brain Injury in Rats

31 March 2020

1 reference

A large screening of angiogenesis biomarkers and their association with neurological outcome after ischemic stroke

31 March 2020

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Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis

31 March 2020

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Hypothermia-induced neurite outgrowth is mediated by tumor necrosis factor-alpha

31 March 2020

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S100B modulates IL-6 release and cytotoxicity from hypothermic brain cells and inhibits hypothermia-induced axonal outgrowth

31 March 2020

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Effect of therapeutic mild hypothermia on the genomics of the hippocampus after moderate traumatic brain injury in rats

31 March 2020

1 reference

Complications and treatment of mild hypothermia

31 March 2020

1 reference

Hibernation in Ground Squirrels Induces State and Species-Specific Tolerance to Hypoxia and Aglycemia: An In Vitro Study in Hippocampal Slices

31 March 2020

1 reference

Protein kinase C epsilon activation delays neuronal depolarization during cardiac arrest in the euthermic arctic ground squirrel

31 March 2020

1 reference

Hypoxia tolerance in mammalian heterotherms.

31 March 2020

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Hibernation in black bears: independence of metabolic suppression from body temperature.

31 March 2020

1 reference

Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs

31 March 2020

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Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain

31 March 2020

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Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase

31 March 2020

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Hypothermia causes a reversible, p53-mediated cell cycle arrest in cultured fibroblasts

31 March 2020

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12 December 2020

CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons

1 reference

12 December 2020

Effect of local mild hypothermia on expression of aquaporin-4 following intracerebral hemorrhage in rats

1 reference

12 December 2020

Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

1 reference

12 December 2020

Therapeutic modulation of brain temperature: relevance to ischemic brain injury

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12 December 2020

Identifiers

DOI

10.1038/NRN3174

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26 August 2017

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