(Q37948677)

25 August 2017

title

Sensing herpes: more than toll (English)

1 reference

25 August 2017

main subject

innate immune response

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A22020814

15 December 2024

1

Jesper Melchjorsen

1 reference

25 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22020814

15 December 2024

publication date

21 October 2011

1 reference

full work available at URL

25 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Frmv.716

1 reference

https://onlinelibrary.wiley.com/doi/pdf/10.1002/rmv.716

15 December 2024

1 reference

Reviews in Medical Virology

15 December 2024

published in

1 reference

25 August 2017

volume

22

1 reference

25 August 2017

issue

2

1 reference

25 August 2017

page(s)

106-121

1 reference

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

25 August 2017

cites work

1 reference

CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons

21 January 2018

1 reference

Mechanisms employed by herpes simplex virus 1 to inhibit the interferon response

21 January 2018

1 reference

Pattern recognition receptors and inflammation

21 January 2018

1 reference

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

1 reference

Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.

21 January 2018

1 reference

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways

21 January 2018

1 reference

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

21 January 2018

1 reference

Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia

21 January 2018

1 reference

Cutting edge: TLR2-mediated proinflammatory cytokine and chemokine production by microglial cells in response to herpes simplex virus

21 January 2018

1 reference

Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain

21 January 2018

1 reference

Lethal encephalitis in myeloid differentiation factor 88-deficient mice infected with herpes simplex virus 1.

21 January 2018

1 reference

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

21 January 2018

1 reference

Herpes simplex virus replication-induced expression of chemokines and proinflammatory cytokines in the eye: implications in herpetic stromal keratitis

21 January 2018

1 reference

Mitochondrial distribution and function in herpes simplex virus-infected cells

21 January 2018

1 reference

Herpes simplex virus-induced expression of 70 kDa heat shock protein (HSP70) requires early protein synthesis but not viral DNA replication

21 January 2018

1 reference

Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

21 January 2018

1 reference

Stepwise release of biologically active HMGB1 during HSV-2 infection

21 January 2018

1 reference

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

21 January 2018

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

Toll-like receptor 3: a link between toll-like receptor, interferon and viruses

21 January 2018

1 reference

Transcriptional signaling by double-stranded RNA: role of TLR3.

21 January 2018

1 reference

When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

21 January 2018

1 reference

TLR3 deficiency in patients with herpes simplex encephalitis

21 January 2018

1 reference

Viral activation of macrophages through TLR-dependent and -independent pathways

21 January 2018

1 reference

mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

1 reference

Toll-like receptor 3 promotes cross-priming to virus-infected cells.

21 January 2018

1 reference

Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: potential of vhs- HSV vectors for dendritic cell-mediated immunotherapy

21 January 2018

1 reference

Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

21 January 2018

1 reference

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

21 January 2018

1 reference

The immunobiology of the TLR9 subfamily

21 January 2018

1 reference

Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9

21 January 2018

1 reference

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

21 January 2018

1 reference

Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells.

21 January 2018

1 reference

Modulation of human plasmacytoid DC function by IFN-lambda1 (IL-29)

21 January 2018

1 reference

Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells

21 January 2018

1 reference

TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain

21 January 2018

1 reference

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

21 January 2018

1 reference

5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

1 reference

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

1 reference

Activation of MDA5 requires higher-order RNA structures generated during virus infection

21 January 2018

1 reference

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

21 January 2018

1 reference

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.

21 January 2018

1 reference

Herpes simplex virus infection is sensed by both Toll-like receptors and retinoic acid-inducible gene- like receptors, which synergize to induce type I interferon production

21 January 2018

1 reference

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

21 January 2018

1 reference

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

21 January 2018

1 reference

Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1.

21 January 2018

1 reference

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

21 January 2018

1 reference

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

21 January 2018

1 reference

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

21 January 2018

1 reference

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

21 January 2018

1 reference

Varicella-zoster virus infection triggers formation of an interleukin-1β (IL-1β)-processing inflammasome complex

21 January 2018

1 reference

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

21 January 2018

1 reference

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling

21 January 2018

1 reference

Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.

21 January 2018

1 reference

Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3.

21 January 2018

1 reference

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

21 January 2018

1 reference

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

21 January 2018

1 reference

Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation

21 January 2018

1 reference

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

21 January 2018

1 reference

Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis

21 January 2018

1 reference

Herpes simplex virus selectively induces expression of the CC chemokine RANTES/CCL5 in macrophages through a mechanism dependent on PKR and ICP0

21 January 2018

1 reference

Requirements for the induction of interleukin-6 by herpes simplex virus-infected leukocytes

21 January 2018

1 reference

Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.

21 January 2018

1 reference

The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3.

21 January 2018

1 reference

PKR regulates TLR2/TLR4-dependent signaling in murine alveolar macrophages.

21 January 2018

1 reference

Induction of interferon-alpha by glycoprotein D of herpes simplex virus: a possible role of chemokine receptors

21 January 2018

1 reference

Virus-cell interactions regulating induction of tumor necrosis factor alpha production in macrophages infected with herpes simplex virus

21 January 2018

1 reference

Induction of signaling pathways by herpes simplex virus type 1 through glycoprotein H peptides

21 January 2018

1 reference

Inhibition of herpes simplex virus type 1-induced interferon synthesis by monoclonal antibodies against viral glycoprotein D and by lysosomotropic drugs

21 January 2018

1 reference

The mannose receptor: linking homeostasis and immunity through sugar recognition

21 January 2018

1 reference

Herpes simplex virus: receptors and ligands for cell entry

21 January 2018

1 reference

Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1

21 January 2018

1 reference

Herpes simplex virus type-1-induced activation of myeloid dendritic cells: the roles of virus cell interaction and paracrine type I IFN secretion.

21 January 2018

1 reference

Requirements for the upregulation of interleukin-6 by herpes simplex virus-infected gingival fibroblasts

21 January 2018

1 reference

Involvement of gD/HVEM interaction in NF-kB-dependent inhibition of apoptosis by HSV-1 gD.

21 January 2018

1 reference

The potential of immunostimulatory CpG DNA for inducing immunity against genital herpes: opportunities and challenges

21 January 2018

1 reference

Molecular adjuvants for mucosal immunity

21 January 2018

1 reference

Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo

21 January 2018

1 reference

CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms.

21 January 2018

1 reference

Genomic DNA released by dying cells induces the maturation of APCs

21 January 2018

1 reference

Modulating vaccine responses with dendritic cells and Toll-like receptors

21 January 2018

1 reference

Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice

21 January 2018

1 reference

CpG motifs in bacterial DNA trigger direct B-cell activation

21 January 2018

1 reference

Therapeutic potential of Toll-like receptor 9 activation

21 January 2018

1 reference

Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection

21 January 2018

1 reference

A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection

21 January 2018

1 reference

Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2.

21 January 2018

1 reference

Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract

21 January 2018

1 reference

Induction of CD8 T-cell-specific systemic and mucosal immunity against herpes simplex virus with CpG-peptide complexes

21 January 2018

1 reference

Treatment of intravaginal HSV-2 infection in mice: a comparison of CpG oligodeoxynucleotides and resiquimod (R-848).

21 January 2018

1 reference

Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production.

21 January 2018

1 reference

Differential signaling by CpG DNA in DCs and B cells: not just TLR9

21 January 2018

1 reference

Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

21 January 2018

1 reference

Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA.

21 January 2018

1 reference

Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection.

21 January 2018

1 reference

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

21 January 2018

1 reference

Topical resiquimod 0.01% gel decreases herpes simplex virus type 2 genital shedding: a randomized, controlled trial

21 January 2018

1 reference

Application of a topical immune response modifier, resiquimod gel, to modify the recurrence rate of recurrent genital herpes: a pilot study

21 January 2018

1 reference

Effect of resiquimod 0.01% gel on lesion healing and viral shedding when applied to genital herpes lesions

21 January 2018

1 reference

Reduction of recurrent HSV disease using imiquimod alone or combined with a glycoprotein vaccine

21 January 2018

1 reference

FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling

21 January 2018

1 reference

FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection

21 January 2018

1 reference

Cytosolic DNA-Activated Human Dendritic Cells Are Potent Activators of the Adaptive Immune Response

21 January 2018

1 reference

Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig

21 January 2018

1 reference

The adjuvant CLDC increases protection of a herpes simplex type 2 glycoprotein D vaccine in guinea pigs

21 January 2018

1 reference

Potent adjuvant activity of cationic liposome-DNA complexes for genital herpes vaccines

21 January 2018

1 reference

Signaling pathway used by HSV-1 to induce NF-kappaB activation: possible role of herpes virus entry receptor A.

21 January 2018

1 reference

Herpes simplex virus type 1 infection stimulates p38/c-Jun N-terminal mitogen-activated protein kinase pathways and activates transcription factor AP-1.

21 January 2018

1 reference

Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICPO

21 January 2018

1 reference

Activation of c-Jun N-terminal kinase (JNK) pathway by HSV-1 immediate early protein ICP0.

21 January 2018

1 reference

Herpes virus proteins ICP0 and BICP0 can activate NF-kappaB by catalyzing IkappaBalpha ubiquitination

21 January 2018

1 reference

Herpes simplex virus type 1 ICP27-dependent activation of NF-kappaB.

21 January 2018

1 reference

Herpes simplex virus ICP27 activation of stress kinases JNK and p38.

21 January 2018

1 reference

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

21 January 2018

1 reference

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

21 January 2018

1 reference

The Role of Toll‐Like Receptors in Herpes Simplex Infection in Neonates

21 January 2018

1 reference

Activation and Evasion of Innate Antiviral Immunity by Herpes Simplex Virus

21 January 2018

5

1 reference

RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them

15 December 2024

29

1 reference

The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations

15 December 2024

63

1 reference

Augmentation of cellular immune responses to bovine herpesvirus-1 glycoprotein D by vaccination with CpG-enhanced plasmid vectors

15 December 2024

97

1 reference

Parameters of CpG oligodeoxynucleotide-induced protection against intravaginal HSV-2 challenge

15 December 2024

109

1 reference

CpG motifs as immune adjuvants

15 December 2024

113

1 reference

Activation of autoreactive B cells by CpG dsDNA

15 December 2024

116

1 reference

Modulation of TH1 and TH2 cytokine production with the immune response modifiers, R-848 and imiquimod

15 December 2024

120

1 reference

Dendritic cell maturation and subsequent enhanced T-cell stimulation induced with the novel synthetic immune response modifier R-848

15 December 2024

121

1 reference

Effect of imiquimod as an adjuvant for immunotherapy of genital HSV in guinea-pigs

15 December 2024

125

1 reference

Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes

15 December 2024

129

1 reference

15 December 2024

Identifiers

DOI

10.1002/RMV.716

1 reference

25 August 2017

1 reference