(Q37874571)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

review article

1 reference

title

Notch signaling in cardiac valve development and disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Luis Luna-Zurita

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

José Luis De La Pompa Mínguez

31 January 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

author name string

Donal MacGrogan

1

1 reference

24 August 2017

Luis Luna-Zurita

2

1 reference

24 August 2017

José Luis de la Pompa

3

1 reference

24 August 2017

language of work or name

1 reference

11 May 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

Birth Defects Research Part A: Clinical and Molecular Teratology

31 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

volume

91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

page(s)

449-459

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

Heart valve development: endothelial cell signaling and differentiation

31 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The bicuspid aortic valve

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The developmental genetics of congenital heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Valvulogenesis: the moving target

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Medical genetics in developing countries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Bicuspid aortic valve is heritable

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Mutations in JAGGED1 gene are predominantly sporadic in Alagille syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

21 January 2018

It's T-ALL about Notch

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Molecular regulation of atrioventricular valvuloseptal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The suppressor of hairless protein participates in notch receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Bicuspid aortic valve: clinical approach and scientific review of a common clinical entity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Molecular genetics of aortic valve disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Mutations in NOTCH1 cause aortic valve disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Insights into degenerative aortic valve disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The genetics of mitral valve prolapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The incidence of congenital heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

HES and HERP families: multiple effectors of the Notch signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Targeted disruption of hesr2 results in atrioventricular valve anomalies that lead to heart dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Spectrum and frequency of jagged1 (JAG1) mutations in Alagille syndrome patients and their families

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Familial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Epidemiology of cardiovascular malformations: prevalence and risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The Notch1 receptor is cleaved constitutively by a furin-like convertase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Characterization of Notch receptor expression in the developing mammalian heart and liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Conditional JAG1 mutation shows the developing heart is more sensitive than developing liver to JAG1 dosage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Notch signaling in cardiac development and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Defective intracellular transport and processing of JAG1 missense mutations in Alagille syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Notch1 represses osteogenic pathways in aortic valve cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Pathogenesis of calcific aortic valve disease: a disease process comes of age (and a good deal more).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Cell biology of cardiac cushion development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Cardiac outflow tract: a review of some embryogenetic aspects of the conotruncal region of the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Hes1 is expressed in the second heart field and is required for outflow tract development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Form and function of developing heart valves: coordination by extracellular matrix and growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

21 January 2018

Tricuspid valve disease

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Bicuspid aortic valve disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Alagille syndrome and the notch signaling pathway: new insights into human development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Jagged1 mutations in alagille syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The epidemiology of valvular heart disease: a growing public health problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Molecular determinants of left and right outflow tract obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

How to make a heart: the origin and regulation of cardiac progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Common pathogenic features of atherosclerosis and calcific aortic stenosis: role of transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

Calcific aortic valve disease: outflow obstruction is the end stage of a systemic disease process

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRA.20815

21 January 2018

Identifiers

DOI

10.1002/BDRA.20815

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21563298%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference