(Q37872765)

24 August 2017

1 reference

title

Biogenesis and cargo selectivity of autophagosomes (English)

1 reference

24 August 2017

Biogenesis and Cargo Selectivity of Autophagosomes (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

1 December 2024

0 references

Hilla Weidberg

1

1 reference

24 August 2017

Elena Shvets

2

1 reference

24 August 2017

Zvulun Elazar

3

1 reference

24 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21548784

1 December 2024

publication date

1 January 2011

1 reference

24 August 2017

2011

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21548784

full work available at URL

1 December 2024

number of pages

32

1 reference

based on heuristic

inferred from page(s)

http://arjournals.annualreviews.org/doi/abs/10.1146/annurev-biochem-052709-094552

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21548784

https://www.annualreviews.org/doi/pdf/10.1146/annurev-biochem-052709-094552

1 December 2024

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Annual Review of Biochemistry

1 December 2024

published in

1 reference

24 August 2017

volume

80

1 reference

24 August 2017

page(s)

125-156

1 reference

The role of autophagy during the early neonatal starvation period

24 August 2017

cites work

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE03029

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1083/JCB.200803137

Cellular differentiation in the kidneys of newborn mice studies with the electron microscope.

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1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The proximal tubule cell in experimental hydronephrosis

1 December 2024

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https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Cytoplasmic components in hepatic cell lysosomes

1 December 2024

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1 reference

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Cytolysomes and mitochondrial degeneration

1 December 2024

4

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

1 December 2024

Functions of lysosomes

5

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes

1 December 2024

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1 reference

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1 December 2024

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Induction of autophagy by amino-acid deprivation in perfused rat liver

1 December 2024

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https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Prelysosomal convergence of autophagic and endocytic pathways

1 December 2024

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1 December 2024

Seminars in cell biology

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1 December 2024

11

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

1 December 2024

12

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes

1 December 2024

13

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

mTOR regulation of autophagy

1 December 2024

14

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Regulation of TORC1 by Rag GTPases in nutrient response

1 December 2024

15

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 December 2024

16

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

DAP1, a novel substrate of mTOR, negatively regulates autophagy

1 December 2024

17

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

1 December 2024

18

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway

1 December 2024

19

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

1 December 2024

20

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A Unified Nomenclature for Yeast Autophagy-Related Genes

1 December 2024

21

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Regulation of mammalian autophagy in physiology and pathophysiology.

1 December 2024

22

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagy, Immunity, and Microbial Adaptations

1 December 2024

23

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae

1 December 2024

24

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae

1 December 2024

25

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The role of the Atg1/ULK1 complex in autophagy regulation

1 December 2024

26

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Tor directly controls the Atg1 kinase complex to regulate autophagy

1 December 2024

27

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiae

1 December 2024

28

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy

1 December 2024

29

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae

1 December 2024

30

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

1 December 2024

31

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

1 December 2024

32

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg101, a novel mammalian autophagy protein interacting with Atg13

1 December 2024

33

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

1 December 2024

34

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

1 December 2024

35

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

1 December 2024

36

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

1 December 2024

37

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex

1 December 2024

38

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagy takes flight in Drosophila

1 December 2024

39

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Great expectations for PIP: phosphoinositides as regulators of signaling during development and disease

1 December 2024

40

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Regulation of autophagy by phosphatidylinositol 3-phosphate

1 December 2024

41

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34

1 December 2024

42

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

1 December 2024

43

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells

1 December 2024

44

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

1 December 2024

45

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

1 December 2024

46

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 December 2024

47

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases.

1 December 2024

48

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

1 December 2024

49

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

1 December 2024

50

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Negative regulation of Vps34 by Cdk mediated phosphorylation

1 December 2024

51

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Ambra1 regulates autophagy and development of the nervous system

1 December 2024

52

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

1 December 2024

53

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

1 December 2024

54

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

1 December 2024

55

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

1 December 2024

56

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.

1 December 2024

57

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

1 December 2024

58

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

1 December 2024

59

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy

1 December 2024

60

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy

1 December 2024

61

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

1 December 2024

62

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

1 December 2024

63

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Dissecting the localization and function of Atg18, Atg21 and Ygr223c

1 December 2024

64

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The relevance of the phosphatidylinositolphosphat-binding motif FRRGT of Atg18 and Atg21 for the Cvt pathway and autophagy

1 December 2024

65

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy

1 December 2024

66

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

1 December 2024

67

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

1 December 2024

68

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

1 December 2024

69

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

1 December 2024

71

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

1 December 2024

72

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

1 December 2024

73

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

1 December 2024

74

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Purification and characterization of autophagosomes from rat hepatocytes

1 December 2024

75

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions.

1 December 2024

76

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

1. Membrane origin for autophagy

1 December 2024

77

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

1 December 2024

78

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Hierarchy of Atg proteins in pre-autophagosomal structure organization

1 December 2024

79

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Current knowledge of the pre-autophagosomal structure (PAS).

1 December 2024

80

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

1 December 2024

81

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

3D tomography reveals connections between the phagophore and endoplasmic reticulum

1 December 2024

82

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Mitochondria supply membranes for autophagosome biogenesis during starvation

1 December 2024

83

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Plasma membrane contributes to the formation of pre-autophagosomal structures

1 December 2024

84

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts

1 December 2024

85

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure

1 December 2024

86

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg17 recruits Atg9 to organize the pre-autophagosomal structure

1 December 2024

87

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg23 is essential for the cytoplasm to vacuole targeting pathway and efficient autophagy but not pexophagy

1 December 2024

88

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg27 is required for autophagy-dependent cycling of Atg9

1 December 2024

89

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg19 mediates a dual interaction cargo sorting mechanism in selective autophagy

1 December 2024

90

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast

1 December 2024

91

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A cycling protein complex required for selective autophagy.

1 December 2024

92

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Arp2 links autophagic machinery with the actin cytoskeleton

1 December 2024

93

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways

1 December 2024

94

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

1 December 2024

95

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway

1 December 2024

96

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae

1 December 2024

97

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg9 sorting from mitochondria is impaired in early secretion and VFT-complex mutants in Saccharomyces cerevisiae

1 December 2024

98

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy

1 December 2024

99

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae

1 December 2024

100

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae

1 December 2024

101

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

1 December 2024

102

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP

1 December 2024

103

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

1 December 2024

104

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis

1 December 2024

105

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Molecular dissection of autophagy: two ubiquitin-like systems

1 December 2024

106

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

1 December 2024

107

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

1 December 2024

108

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Role of autophagy and autophagy genes in inflammatory bowel disease

1 December 2024

109

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

1 December 2024

110

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

1 December 2024

111

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 December 2024

113

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Discovery of Atg5/Atg7-independent alternative macroautophagy

1 December 2024

114

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

1 December 2024

115

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex

1 December 2024

116

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28

1 December 2024

117

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

1 December 2024

118

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

LC3 conjugation system in mammalian autophagy

1 December 2024

119

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

1 December 2024

120

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

1 December 2024

121

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A

1 December 2024

122

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates

1 December 2024

123

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

1 December 2024

124

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Dissection of autophagosome biogenesis into distinct nucleation and expansion steps

1 December 2024

125

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg8 controls phagophore expansion during autophagosome formation

1 December 2024

126

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

1 December 2024

127

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Cvt pathway as a model for selective autophagy

1 December 2024

128

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 December 2024

129

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

1 December 2024

130

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes

1 December 2024

131

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice

1 December 2024

132

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation

1 December 2024

133

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Regulation of autophagy by the p300 acetyltransferase

1 December 2024

134

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

1 December 2024

135

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Regulation of the autophagy protein LC3 by phosphorylation

1 December 2024

136

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

1 December 2024

137

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p

1 December 2024

138

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

ATG systems from the protein structural point of view

1 December 2024

139

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Structure of GABARAP in two conformations: implications for GABA(A) receptor localization and tubulin binding

1 December 2024

140

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

1 December 2024

141

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy

1 December 2024

142

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Identification of essential residues for the C-terminal cleavage of the mammalian LC3: a lesson from yeast Atg8.

1 December 2024

143

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy

1 December 2024

144

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Structural basis for sorting mechanism of p62 in selective autophagy

1 December 2024

145

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 December 2024

146

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Structural basis of target recognition by Atg8/LC3 during selective autophagy

1 December 2024

147

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

1 December 2024

148

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes

1 December 2024

149

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

1 December 2024

150

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes

1 December 2024

151

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

1 December 2024

152

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Dynein mutations impair autophagic clearance of aggregate-prone proteins

1 December 2024

153

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport

1 December 2024

154

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation

1 December 2024

155

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 December 2024

156

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

1 December 2024

157

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes

1 December 2024

158

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome

1 December 2024

159

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

1 December 2024

160

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

1 December 2024

161

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

1 December 2024

162

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

ESCRTs and Fab1 regulate distinct steps of autophagy

1 December 2024

163

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells

1 December 2024

164

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

1 December 2024

165

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

1 December 2024

166

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Role for Rab7 in maturation of late autophagic vacuoles

1 December 2024

167

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes

1 December 2024

168

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole

1 December 2024

169

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion

1 December 2024

170

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways

1 December 2024

171

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

1 December 2024

172

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p

1 December 2024

173

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Selective Transport of -Mannosidase by Autophagic Pathways: STRUCTURAL BASIS FOR CARGO RECOGNITION BY Atg19 AND Atg34

1 December 2024

174

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Lap3 is a selective target of autophagy in yeast, Saccharomyces cerevisiae

1 December 2024

175

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Signal integration and diversification through the p62 scaffold protein

1 December 2024

176

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

1 December 2024

177

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

1 December 2024

178

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.

1 December 2024

179

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

1 December 2024

180

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

1 December 2024

181

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.

1 December 2024

182

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

1 December 2024

183

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagy suppresses tumorigenesis through elimination of p62

1 December 2024

184

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation

1 December 2024

185

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

1 December 2024

186

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway.

1 December 2024

187

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Listeria monocytogenes ActA-mediated escape from autophagic recognition

1 December 2024

188

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties.

1 December 2024

189

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Selective autophagy: ubiquitin-mediated recognition and beyond

1 December 2024

190

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover

1 December 2024

192

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity

1 December 2024

193

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming

1 December 2024

194

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

1 December 2024

195

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

1 December 2024

196

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

1 December 2024

197

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Molecular mechanism and physiological role of pexophagy

1 December 2024

198

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A yeast MAPK cascade regulates pexophagy but not other autophagy pathways.

1 December 2024

199

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate

1 December 2024

201

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Peroxisome degradation requires catalytically active sterol glucosyltransferase with a GRAM domain

1 December 2024

202

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

PI4P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy.

1 December 2024

203

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Peroxisome size provides insights into the function of autophagy-related proteins

1 December 2024

204

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Excess peroxisomes are degraded by autophagic machinery in mammals

1 December 2024

205

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Regulation of autophagy by ROS: physiology and pathology

1 December 2024

206

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

1 December 2024

Mitophagy

207

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Uth1p is involved in the autophagic degradation of mitochondria

1 December 2024

208

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival

1 December 2024

209

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

A genomic screen for yeast mutants defective in selective mitochondria autophagy

1 December 2024

210

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg32 is a mitochondrial protein that confers selectivity during mitophagy

1 December 2024

211

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy

1 December 2024

212

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Atg8-family interacting motif crucial for selective autophagy

1 December 2024

213

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 December 2024

214

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Nix is a selective autophagy receptor for mitochondrial clearance

1 December 2024

215

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Homozygous PINK1 C-terminus mutation causing early-onset parkinsonism

1 December 2024

216

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Novel PINK1 mutations in early-onset parkinsonism

1 December 2024

217

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

1 December 2024

218

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy

1 December 2024

219

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

The MAP1-LC3 conjugation system is involved in lipid droplet formation

1 December 2024

220

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Autophagy regulates lipid metabolism

1 December 2024

221

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

1 December 2024

222

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

1 December 2024

223

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Altered autophagy in human adipose tissues in obesity

1 December 2024

224

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes

1 December 2024

225

1 reference

https://api.crossref.org/works/10.1146/ANNUREV-BIOCHEM-052709-094552

1 December 2024

Identifiers

1 reference

24 August 2017

1 reference