(Q37788542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Renal fibrosis: novel insights into mechanisms and therapeutic targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Tammo Ostendorf

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Jürgen Floege

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

14 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Nephrology

13 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

643-656

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20838416%20AND%20SRC:MED&resulttype=core&format=json

Biomarkers for epithelial-mesenchymal transitions

13 February 2020

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Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

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Abnormal growth and clonal proliferation of fibroblasts in an animal model of unilateral ureteral obstruction.

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Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acute renal failure in rats

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Smooth muscle alpha-actin deficiency in myofibroblasts leads to enhanced renal tissue fibrosis

31 March 2020

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Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury

31 March 2020

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PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis

31 March 2020

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Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis

31 March 2020

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Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6-nephrectomized rats

31 March 2020

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PDGF-receptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys

31 March 2020

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A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D

31 March 2020

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Localization of PDGF alpha-receptor in the developing and mature human kidney

31 March 2020

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PDGF-C Expression in the Developing and Normal Adult Human Kidney and in Glomerular Diseases

31 March 2020

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PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.

31 March 2020

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A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling

31 March 2020

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Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease

31 March 2020

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Latent TGF-beta1 protects against crescentic glomerulonephritis

31 March 2020

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Bone morphogenic protein-7 and the kidney: current concepts and open questions

31 March 2020

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Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models

31 March 2020

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BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

31 March 2020

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Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney

31 March 2020

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Modulator of bone morphogenetic protein activity in the progression of kidney diseases

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Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome.

31 March 2020

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Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

31 March 2020

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Methylation determines fibroblast activation and fibrogenesis in the kidney

31 March 2020

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Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy

31 March 2020

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MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

31 March 2020

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MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

31 March 2020

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Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies

31 March 2020

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Early epithelial phenotypic changes predict graft fibrosis

31 March 2020

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31 March 2020

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Autophagy is a component of epithelial cell fate in obstructive uropathy

31 March 2020

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Increased E-cadherin expression in the ligated kidney following unilateral ureteric obstruction

31 March 2020

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

31 March 2020

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Intrinsic epithelial cells repair the kidney after injury

31 March 2020

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Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis

31 March 2020

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Leaked protein and interstitial damage in the kidney: is complement the missing link?

31 March 2020

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C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria.

31 March 2020

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C5b-9 regulates peritubular myofibroblast accumulation in experimental focal segmental glomerulosclerosis

31 March 2020

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Complement C5 mediates experimental tubulointerstitial fibrosis

31 March 2020

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Anaphylatoxin C5a contributes to the pathogenesis of cisplatin-induced nephrotoxicity

31 March 2020

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Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

31 March 2020

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Endoplasmic reticulum stress in proteinuric kidney disease

31 March 2020

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Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury.

31 March 2020

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Autophagy: molecular machinery, regulation, and implications for renal pathophysiology

31 March 2020

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Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

31 March 2020

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Autophagy protects renal tubular cells against cyclosporine toxicity

31 March 2020

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DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death.

31 March 2020

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

31 March 2020

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CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice

31 March 2020

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An update on the lipid nephrotoxicity hypothesis

31 March 2020

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Niacin improves renal lipid metabolism and slows progression in chronic kidney disease

31 March 2020

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Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure

31 March 2020

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Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney

31 March 2020

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Peroxisome proliferator-activated receptors and renal diseases

31 March 2020

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Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus

31 March 2020

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PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta

31 March 2020

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Hypoxia-inducible factor signaling in the development of tissue fibrosis

31 March 2020

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Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis

31 March 2020

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Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition

31 March 2020

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Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice.

31 March 2020

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31 March 2020

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Loss of renal microvascular integrity in postnatal Crim1 hypomorphic transgenic mice

31 March 2020

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Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease

31 March 2020

1 reference

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Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes

31 March 2020

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Fibrocytes are involved in the pathogenesis of human chronic kidney disease.

31 March 2020

1 reference

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Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Fibrotic disease and the T(H)1/T(H)2 paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Bone marrow-derived cells do not contribute significantly to collagen I synthesis in a murine model of renal fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Bone marrow-derived myofibroblasts contribute to the renal interstitial myofibroblast population and produce procollagen I after ischemia/reperfusion in rats

31 March 2020

1 reference

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Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis

31 March 2020

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The regulation of inflammation by galectin-3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Macrophage Wnt7b is critical for kidney repair and regeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Development of monocytes, macrophages, and dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Macrophage phenotype and renal fibrosis in obstructive nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

By homing to the kidney, activated macrophages potently exacerbate renal injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Adoptive transfer of macrophages ameliorates renal fibrosis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Lymphatic vessels develop during tubulointerstitial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Lymphatic Microvessels in the Rat Remnant Kidney Model of Renal Fibrosis: Aminopeptidase P and Podoplanin Are Discriminatory Markers for Endothelial Cells of Blood and Lymphatic Vessels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Pathways to nephron loss starting from glomerular diseases-insights from animal models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Disturbance of lymph circulation develops renal fibrosis in rats with or without contralateral nephrectomy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Lymphatic neoangiogenesis in human renal allografts: results from sequential protocol biopsies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Role of stem cell factor and mast cells in the progression of chronic glomerulonephritides.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Mast cells: the forgotten cells of renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

A pathogenetic role for mast cells in experimental crescentic glomerulonephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Mast cell-mediated remodeling and fibrinolytic activity protect against fatal glomerulonephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Role of mast cells in the development of renal fibrosis: use of mast cell-deficient rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Role of mast cells in experimental anti-glomerular basement membrane glomerulonephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Mast cells decrease renal fibrosis in unilateral ureteral obstruction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Mast cells: a unique source of renin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Contribution of chymase-dependent angiotensin II formation to the progression of tubulointerstitial fibrosis in obstructed kidneys in hamsters

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Transglutaminase inhibition ameliorates experimental diabetic nephropathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Laminin alpha4-null mutant mice develop chronic kidney disease with persistent overexpression of platelet-derived growth factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

C/EBP-beta modulates transcription of tubulointerstitial nephritis antigen in obstructive uropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Pirfenidone is renoprotective in diabetic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Renoprotective properties of pirfenidone in subtotally nephrectomized rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Pirfenidone: an anti-fibrotic therapy for progressive kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Pirfenidone Slows Renal Function Decline in Patients with Focal Segmental Glomerulosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

The origin of renal fibroblasts and progression of kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Is there such a thing as a renal stem cell?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Stem cell options for kidney disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Evaluation of Tubulointerstitial Lesions' Severity in Patients with Glomerulonephritides: An NMR-Based Metabonomic Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Biomarkers in acute and chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Urinary L-type fatty acid-binding protein can reflect renal tubulointerstitial injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Renal L-type fatty acid--binding protein in acute ischemic injury.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Renal L-type fatty acid-binding protein mediates the bezafibrate reduction of cisplatin-induced acute kidney injury

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Urine podocyte mRNAs mark progression of renal disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Noninvasive diagnosis of acute rejection of renal allografts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Urinary procollagen III aminoterminal propeptide (PIIINP): a fibrotest for the nephrologist.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Renal gene and protein expression signatures for prediction of kidney disease progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Renal clearance of quantum dots

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

A novel signaling pathway: fibroblast nicotinic receptor alpha1 binds urokinase and promotes renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

N-acetyl-seryl-aspartyl-lysyl-proline attenuates renal injury and dysfunction in hypertensive rats with reduced renal mass: council for high blood pressure research

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Loss of TIMP3 enhances interstitial nephritis and fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

The orphan nuclear receptor SHP attenuates renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Endogenous relaxin is a naturally occurring modulator of experimental renal tubulointerstitial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Nestin expression in the kidney with an obstructed ureter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

CTGF inhibits BMP-7 signaling in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2010.120

Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

31 March 2020

1 reference

12 December 2020

Expression of PDGF alpha-receptor in renal arteriosclerosis and rejecting renal transplants

1 reference

12 December 2020

Functional, histological and biochemical consequences of renal lymph disorder in mononephrectomized rats

1 reference

12 December 2020

Actin filaments in human renal tubulo-interstitial fibrosis: significance for the concept of epithelial-myofibroblast transformation.

1 reference

12 December 2020

Role of mast cell tryptase in renal interstitial fibrosis

1 reference

12 December 2020

Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney

1 reference

12 December 2020