(Q37765370)

22 August 2017

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title

PPAR modulation of kinase-linked receptor signaling in physiology and disease (English)

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22 August 2017

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Nicolas Rotman

1

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22 August 2017

Walter Wahli

series ordinal

2

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22 August 2017

publication date

1 June 2010

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22 August 2017

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22 August 2017

volume

25

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22 August 2017

issue

3

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22 August 2017

page(s)

176-185

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MAPK kinases as nucleo-cytoplasmic shuttles for PPARgamma

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Modulation of PPAR activity via phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Trafficking of receptor tyrosine kinases to the nucleus

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor gamma agonists as insulin sensitizers: from the discovery to recent progress

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Be fit or be sick: peroxisome proliferator-activated receptors are down the road

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

21 January 2018

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From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions

21 January 2018

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Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Kinase signaling cascades that modulate peroxisome proliferator-activated receptors

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

PPARgamma ligand attenuates PDGF-induced mesangial cell proliferation: role of MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer ce

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Fish oil inhibits human lung carcinoma cell growth by suppressing integrin-linked kinase

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor {delta} regulates extracellular matrix and apoptosis of vascular smooth muscle cells through the activation of transforming growth factor-{beta}1/Smad3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Pro-MMP-2 activation by the PPARgamma agonist, ciglitazone, induces cell invasion through the generation of ROS and the activation of ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

PPARdelta activation inhibits angiotensin II induced cardiomyocyte hypertrophy by suppressing intracellular Ca2+ signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Apoptosis induced by troglitazone is both peroxisome proliferator-activated receptor-gamma- and ERK-dependent in human non-small lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Nuclear localization of EGF receptor and its potential new role as a transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

A new mechanism involving ERK contributes to rosiglitazone inhibition of tumor necrosis factor-alpha and interferon-gamma inflammatory effects in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

PPARs Mediate Lipid Signaling in Inflammation and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

A novel PPARgamma agonist, KR62776, suppresses RANKL-induced osteoclast differentiation and activity by inhibiting MAP kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Agonists of peroxisome proliferators-activated receptors (PPAR) alpha, beta/delta or gamma reduce transforming growth factor (TGF)-beta-induced proteoglycans' production in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

FGF21: a missing link in the biology of fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-dependent tumor specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

Differential Regulation of Vascular Endothelial Growth Factor Expression by Peroxisome Proliferator-activated Receptors in Bladder Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00018.2010

10.1152/PHYSIOL.00018.2010

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference