(Q37523207)

20 August 2017

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title

Genetic prognostic and predictive markers in colorectal cancer (English)

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20 August 2017

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Charles Swanton

3

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Ian Tomlinson

series ordinal

5

object named as

Ian Tomlinson

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20 August 2017

2

Elaine Johnstone

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20 August 2017

Axel Walther

1

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20 August 2017

Rachel Midgley

series ordinal

4

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20 August 2017

David Kerr

series ordinal

6

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20 August 2017

language of work or name

English

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publication date

18 June 2009

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20 August 2017

published in

Nature Reviews Cancer

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20 August 2017

volume

9

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20 August 2017

issue

7

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20 August 2017

page(s)

489-499

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Systemic treatment of colorectal cancer

20 August 2017

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31 March 2020

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High-frequency microsatellite instability predicts better chemosensitivity to high-dose 5-fluorouracil plus leucovorin chemotherapy for stage IV sporadic colorectal cancer after palliative bowel resection

31 March 2020

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Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.

31 March 2020

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Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines

31 March 2020

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Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803

31 March 2020

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Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

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31 March 2020

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31 March 2020

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Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients.

31 March 2020

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Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Glutathione S-Transferase P1 Polymorphism (Ile105Val) Predicts Cumulative Neuropathy in Patients Receiving Oxaliplatin-Based Chemotherapy

31 March 2020

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Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy.

31 March 2020

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A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer

31 March 2020

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Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

31 March 2020

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Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

31 March 2020

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Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

31 March 2020

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A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

31 March 2020

1 reference

A common variant on chromosome 9p21 affects the risk of myocardial infarction

31 March 2020

1 reference

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

31 March 2020

1 reference

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

31 March 2020

1 reference

Cancer-susceptibility genes. Gatekeepers and caretakers

31 March 2020

1 reference

Genomic instability occurs in colorectal carcinomas but not in adenomas

31 March 2020

1 reference

Genomic and epigenetic instability in colorectal cancer pathogenesis

31 March 2020

1 reference

Colorectal cancer and genetic alterations in the Wnt pathway

31 March 2020

1 reference

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

31 March 2020

1 reference

Frameshift mutator mutations

31 March 2020

1 reference

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

31 March 2020

1 reference

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

31 March 2020

1 reference

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

31 March 2020

1 reference

Inactivation of hCDC4 can cause chromosomal instability

31 March 2020

1 reference

CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability

31 March 2020

1 reference

Epidermal growth factor-related peptides and their receptors in human malignancies

31 March 2020

1 reference

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

31 March 2020

1 reference

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

31 March 2020

1 reference

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

31 March 2020

1 reference

CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer

31 March 2020

1 reference

Metabolism and mechanism of action of 5-fluorouracil

31 March 2020

1 reference

Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study

31 March 2020

1 reference

12 December 2020

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma

1 reference

12 December 2020

Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

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12 December 2020

Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999.

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12 December 2020

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

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12 December 2020

Classification of Dukes' B and C colorectal cancers using expression arrays

1 reference

12 December 2020

Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression

1 reference

12 December 2020

A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients

1 reference

12 December 2020

Chemotherapeutic implications in microsatellite unstable colorectal cancer

1 reference

12 December 2020

Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy

1 reference

12 December 2020

Polymorphism in the thymidylate synthase promoter enhancer region in colorectal cancer.

1 reference

12 December 2020

A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity

1 reference

12 December 2020

Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer

1 reference

12 December 2020

Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer

1 reference

12 December 2020

Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study.

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12 December 2020

Identifiers

DOI

10.1038/NRC2645

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20 August 2017

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