(Q37417482)

20 August 2017

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title

Integration of cytokine and heterologous receptor signaling pathways (English)

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cytokine-mediated signaling pathway

20 August 2017

main subject

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0019221

corrigendum / erratum

Erratum: Corrigendum: Integration of cytokine and heterologous receptor signaling pathways

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Jelena S Bezbradica

1

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Ruslan Medzhitov

series ordinal

2

object named as

Ruslan Medzhitov

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20 August 2017

language of work or name

English

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publication date

19 March 2009

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20 August 2017

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20 August 2017

volume

10

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20 August 2017

issue

4

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20 August 2017

page(s)

333-339

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The JAK-STAT signaling pathway: input and output integration

20 August 2017

cites work

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Differential modulation of stimulatory and inhibitory Fc gamma receptors on human monocytes by Th1 and Th2 cytokines

21 January 2018

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Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

21 January 2018

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Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

21 January 2018

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The IL-15R alpha chain signals through association with Syk in human B cells

21 January 2018

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Mast Cells Express Novel Functional IL-15 Receptor α Isoforms

21 January 2018

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TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex

21 January 2018

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NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1

21 January 2018

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12 December 2020

Signaling by type I and II cytokine receptors: ten years after

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12 December 2020

Enforced expression of Bcl-2 restores the number of NK cells, but does not rescue the impaired development of NKT cells or intraepithelial lymphocytes, in IL-2/IL-15 receptor beta-chain-deficient mice

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12 December 2020

Involvement of SHP-2 in multiple aspects of IL-2 signaling: evidence for a positive regulatory role

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12 December 2020

Mutational switch of an IL-6 response to an interferon-gamma-like response

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12 December 2020

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

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12 December 2020

RETRACTED: A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control

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12 December 2020

Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages.

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12 December 2020

Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma

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12 December 2020

IL-15/IL-15 receptor biology: a guided tour through an expanding universe

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12 December 2020

A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways

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12 December 2020

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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12 December 2020

Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway

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12 December 2020

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

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12 December 2020

Alternative activation of STAT1 and STAT3 in response to interferon-gamma

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12 December 2020

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

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12 December 2020

SOCS-1 participates in negative regulation of LPS responses

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12 December 2020

Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation

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12 December 2020

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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12 December 2020

Transient inhibition of interleukin 4 signaling by T cell receptor ligation

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12 December 2020

Cytokine signal transduction

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12 December 2020

Upregulation of type I interferon receptor by IFN-gamma

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12 December 2020

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

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12 December 2020

A role for the phagosome in cytokine secretion

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12 December 2020

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

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12 December 2020

Signal integration between IFNgamma and TLR signalling pathways in macrophages

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12 December 2020

Jaks and STATs: biological implications

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12 December 2020

A mutation of the mu transmembrane that disrupts endoplasmic reticulum retention. Effects on association with accessory proteins and signal transduction.

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12 December 2020

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes

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12 December 2020

Sensitization of IFN-γ Jak-STAT signaling during macrophage activation

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12 December 2020

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

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12 December 2020

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12 December 2020

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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12 December 2020

The assembly of diverse immune receptors is focused on a polar membrane-embedded interaction site

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12 December 2020

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

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12 December 2020

T cells use two directionally distinct pathways for cytokine secretion.

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12 December 2020

Demethylation of a specific hypersensitive site in the Th2 locus control region

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12 December 2020

Roles for glycosylation of cell surface receptors involved in cellular immune recognition

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12 December 2020

IL-4-dependent induction of BCL-2 and BCL-X(L)IN activated T lymphocytes through a STAT6- and pi 3-kinase-independent pathway

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12 December 2020

Colocalization of the IL-12 receptor and FcgammaRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-gamma

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12 December 2020

Th17 cell differentiation: the long and winding road

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12 December 2020

Role of the extracellular and transmembrane domain of Ig-alpha/beta in assembly of the B cell antigen receptor (BCR).

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12 December 2020

TAM receptors are pleiotropic inhibitors of the innate immune response

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12 December 2020

Interferon-γ: an overview of signals, mechanisms and functions

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12 December 2020

Biologic consequences of Stat1-independent IFN signaling.

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12 December 2020

Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

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12 December 2020

Components of a Stat recognition code: evidence for two layers of molecular selectivity

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12 December 2020

Dendritic cells prime natural killer cells by trans-presenting interleukin 15

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12 December 2020

STAT family of transcription factors in cytokine-mediated biological responses

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12 December 2020

NK cell survival mediated through the regulatory synapse with human DCs requires IL-15Ralpha

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12 December 2020

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

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12 December 2020

Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

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12 December 2020

Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells

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12 December 2020

'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages

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12 December 2020

PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs

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12 December 2020

IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells

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12 December 2020

The biology of interleukin-2.

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12 December 2020

Stat5 activation plays a critical role in Th2 differentiation

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12 December 2020

NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway

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12 December 2020

Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling

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12 December 2020

Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

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12 December 2020

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

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12 December 2020

Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity

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12 December 2020

Serine phosphorylation of STATs

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12 December 2020

The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells

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12 December 2020

The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines

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12 December 2020

IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.

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12 December 2020

Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity

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12 December 2020

SOCS proteins, cytokine signalling and immune regulation

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12 December 2020

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

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12 December 2020

Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes

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12 December 2020

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

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12 December 2020

JAK2, a third member of the JAK family of protein tyrosine kinases

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12 December 2020

Expression of a functional high-affinity IgG receptor, Fc gamma RI, on human mast cells: Up-regulation by IFN-gamma

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12 December 2020

Protein-protein interactions in the membrane: sequence, structural, and biological motifs

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12 December 2020

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

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12 December 2020

Inhibition of IFN-alpha signaling by a PKC- and protein tyrosine phosphatase SHP-2-dependent pathway

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12 December 2020

Immune complexes suppress IFN-gamma signaling by activation of the FcgammaRI pathway.

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12 December 2020

Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease

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12 December 2020

LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages.

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12 December 2020

The Janus protein tyrosine kinase family and its role in cytokine signaling

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12 December 2020

The IL-4 receptor: signaling mechanisms and biologic functions

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12 December 2020

Priming for T helper type 2 differentiation by interleukin 2-mediated induction of interleukin 4 receptor alpha-chain expression

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12 December 2020

IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor

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12 December 2020

Jaks and cytokine receptors--an intimate relationship

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12 December 2020

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma : a molecular basis for priming and synergism with bacterial lipopolysaccharide

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12 December 2020

Role of IRS-2 in insulin and cytokine signalling

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12 December 2020

The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

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12 December 2020

Signaling through the hematopoietic cytokine receptors.

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12 December 2020

Interleukin-15 (IL-15) induces NF-kappaB activation and IL-8 production in human neutrophils

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12 December 2020

NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.

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12 December 2020

Mechanism of crosstalk inhibition of IL-6 signaling in response to LPS and TNFα

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12 December 2020

The organizing principle in the formation of the T cell receptor-CD3 complex.

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12 December 2020

Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors

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12 December 2020

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

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12 December 2020

Cloning members of protein-tyrosine kinase family using polymerase chain reaction

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12 December 2020

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

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12 December 2020

Sweet 'n' sour: the impact of differential glycosylation on T cell responses

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12 December 2020

CD8(+) T lymphocytes induce polarized exocytosis of secretory lysosomes by dendritic cells with release of interleukin-1beta and cathepsin D.

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12 December 2020

A role for the immunological synapse in lineage commitment of CD4 lymphocytes

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12 December 2020

FcgammaRIV: a novel FcR with distinct IgG subclass specificity

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12 December 2020

Identifiers

DOI

10.1038/NI.1713

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20 August 2017

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