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AMPK: a key regulator of energy balance in the single cell and the whole organism.
scientific article published on September 2008
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scholarly article
1 reference
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Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
AMPK: a key regulator of energy balance in the single cell and the whole organism
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
author
Grahame Hardie
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
author name string
D G Hardie
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
retrieved
19 August 2017
language of work or name
English
0 references
publication date
1 September 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
published in
International Journal of Obesity
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
volume
32 Suppl 4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
page(s)
S7-12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
cites work
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LKB1-dependent signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fatal congenital heart glycogenosis caused by a recurrent activating R531Q mutation in the gamma 2-subunit of AMP-activated protein kinase (PRKAG2), not by phosphorylase kinase deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMP-activated protein kinase plays a role in the control of food intake
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TSC2 mediates cellular energy response to control cell growth and survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial dysfunction and type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AMP-activated protein kinase: a master switch in glucose and lipid metabolism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of AMP-activated protein kinase in mechanism of metformin action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Possible involvement of AMP-activated protein kinase in obesity resistance induced by respiratory uncoupling in white fat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved glucose homeostasis in mice overexpressing human UCP3: a role for AMP-kinase?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FIJO.2008.116
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/IJO.2008.116
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
PubMed publication ID
18719601
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18719601
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719601%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 January 2020
ResearchGate publication ID
51433198
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