(Q37073404)

English

Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures

scientific article published on 15 May 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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1 reference

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Hendrik Vilstrup

6

object named as

Hendrik Vilstrup

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Susanne Keiding

8

object named as

Susanne Keiding

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Sherry Dadsetan

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Eva Kukolj

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Lasse K Bak

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Michael Sørensen

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Peter Ott

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Arne Schousboe

7

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Europe PubMed Central

PMC publication ID

18 August 2017

Helle S Waagepetersen

9

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Europe PubMed Central

PMC publication ID

18 August 2017

publication date

15 May 2013

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Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Cerebral Blood Flow & Metabolism

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Europe PubMed Central

PMC publication ID

18 August 2017

33

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Europe PubMed Central

PMC publication ID

18 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1235-1241

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Glutamine in the pathogenesis of hepatic encephalopathy: the trojan horse hypothesis revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Neuroimaging in acute liver failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Pathogenetic mechanisms of hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Glutamine: a Trojan horse in ammonia neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Neuronal-glial glucose oxidation and glutamatergic-GABAergic function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Effect of glutamine synthetase inhibition on astrocyte swelling and altered astroglial protein expression during hyperammonemia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Effect of treatment with the Molecular Adsorbents Recirculating System on arterial amino acid levels and cerebral amino acid metabolism in patients with hepatic encephalopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Glutamate uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

The metabolic fate of 13N-labeled ammonia in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Fine structural localization of glutamine synthetase in astrocytes of rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

29 September 2017

Proton magnetic resonance spectroscopy of the brain in symptomatic and asymptomatic patients with liver cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

Metabolism of [U-13C5] glutamine in cultured astrocytes studied by NMR spectroscopy: first evidence of astrocytic pyruvate recycling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

Uptake, release, and metabolism of alanine in neurons and astrocytes in primary cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

Transamination of amino acids in homogenates of rat brzain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

Amino acid changes in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

Precursors of glutamic acid nitrogen in primary neuronal cultures: studies with 15N.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

Ammonia and related amino acids in the pathogenesis of brain edema in acute ischemic liver failure in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

27 June 2018

siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Demonstration of neuron-glia transfer of precursors for GABA biosynthesis in a co-culture system of dissociated mouse cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Metabolic compartments in vivo. Ammonia and glutamic acid metabolism in brain and liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Trafficking between glia and neurons of TCA cycle intermediates and related metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734774

4 September 2018

Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23673435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of amino acids as their tert.-butyldimethylsilyl derivatives by gas-liquid chromatography and mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/23673435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte metabolism of [15N]glutamine: implications for the glutamine-glutamate cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/23673435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte swelling in liver failure: role of glutamine and benzodiazepines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23673435

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/JCBFM.2013.73

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

0 references

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