(Q37038404)

17 August 2017

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title

Glucose neurotoxicity (English)

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17 August 2017

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David R Tomlinson

1

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17 August 2017

Natalie J Gardiner

series ordinal

2

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17 August 2017

language of work or name

English

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publication date

1 January 2008

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Nature Reviews Neuroscience

17 August 2017

published in

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17 August 2017

volume

9

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17 August 2017

issue

1

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17 August 2017

page(s)

36-45

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Immunohistochemical localization and quantification of glucose transporters in the mouse brain

17 August 2017

cites work

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Glucose transport in primary cultured neurons

31 March 2020

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Glucose and leucine uptake by rat dorsal root ganglia is not insulin sensitive

31 March 2020

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The selfish brain: competition for energy resources

31 March 2020

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GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues

31 March 2020

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Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus

31 March 2020

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Localization of glucokinase gene expression in the rat brain

31 March 2020

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Role of neuropeptides in appetite regulation and obesity--a review.

31 March 2020

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Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons

31 March 2020

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Free sugars in alloxan diabetic rat nerve

31 March 2020

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Formation of Polyols by the Lens of the Rat with ‘Sugar’ Cataract

31 March 2020

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Sorbitol Pathway: Presence in Nerve and Cord with Substrate Accumulation in Diabetes

31 March 2020

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In Vitro Studies of the Substrates for Energy Production and the Effects of Insulin on Glucose Utilization in the Neural Components of Peripheral Nerve

31 March 2020

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Role of aldose reductase and sorbitol in maintaining the medullary intracellular milieu

31 March 2020

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Depletion of myo-inositol and amino acids in galactosemic neuropathy

31 March 2020

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Immunohistochemical localization of aldose reductase. I. Enzyme purification and antibody preparation--localization in peripheral nerve, artery, and testis

31 March 2020

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Peripheral nerve structure and function in experimental diabetes

31 March 2020

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Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil

31 March 2020

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

31 March 2020

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An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense

31 March 2020

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Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst

31 March 2020

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Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited

31 March 2020

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Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats.

31 March 2020

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Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats

31 March 2020

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Advanced glycation end-products: a review

31 March 2020

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Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?

31 March 2020

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Modification of the glyoxalase system in human red blood cells by glucose in vitro

31 March 2020

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Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

31 March 2020

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Aminoguanidine and diabetic neuropathy

31 March 2020

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Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications

31 March 2020

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A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy

31 March 2020

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Mitogen-activated protein kinases as glucose transducers for diabetic complications

31 March 2020

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Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase

31 March 2020

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NERVE CONDUCTION CHANGES IN EXPERIMENTAL DIABETES.

31 March 2020

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Diabetic neuropathy: Influence of age, sex, metabolic control, and duration of diabetes on motor conduction velocity

31 March 2020

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Transcriptional regulation by the MAP kinase signaling cascades

31 March 2020

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Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.

31 March 2020

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Simulations of conduction in uniform myelinated fibers. Relative sensitivity to changes in nodal and internodal parameters

31 March 2020

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Neurons undergo apoptosis in animal and cell culture models of diabetes.

31 March 2020

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p73-dependent apoptosis through death receptor: impairment by human cytomegalovirus infection

31 March 2020

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The invulnerability of adult neurons: a critical role for p73.

31 March 2020

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Sensory neurons with activated caspase-3 survive long-term experimental diabetes

31 March 2020

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Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy

31 March 2020

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Axonal transport of endogenous nerve growth factor (NGF) and NGF receptor in experimental diabetic neuropathy

31 March 2020

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Target tissue production and axonal transport of neurotrophin-3 are reduced in streptozotocin-diabetic rats

31 March 2020

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Effect of streptozotocin-induced diabetes on NGF, P75(NTR) and TrkA content of prevertebral and paravertebral rat sympathetic ganglia

31 March 2020

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Streptozotocin-induced diabetes causes metabolic changes and alterations in neurotrophin content and retrograde transport in the cervical vagus nerve

31 March 2020

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Human recombinant nerve growth factor replaces deficient neurotrophic support in the diabetic rat

31 March 2020

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Targeted delivery of nerve growth factor via fibronectin conduits assists nerve regeneration in control and diabetic rats

31 March 2020

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Neurogenic cutaneous vasodilatation and plasma extravasation in diabetic rats: effect of insulin and nerve growth factor

31 March 2020

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Neurotrophin-3-induced production of nerve growth factor is suppressed in Schwann cells exposed to high glucose: involvement of the polyol pathway

31 March 2020

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Therapeutic effects of aldose reductase inhibitor on experimental diabetic neuropathy through synthesis/secretion of nerve growth factor

31 March 2020

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A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy

31 March 2020

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Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy

31 March 2020

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Taurine counteracts oxidative stress and nerve growth factor deficit in early experimental diabetic neuropathy

31 March 2020

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Depletion of phospholipid arachidonoyl-containing molecular species in a human Schwann cell line grown in elevated glucose and their restoration by an aldose reductase inhibitor

31 March 2020

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Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress.

31 March 2020

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Organizing principles of the axoglial apparatus

31 March 2020

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Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy

31 March 2020

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Axo-glial dysjunction. A novel structural lesion that accounts for poorly reversible slowing of nerve conduction in the spontaneously diabetic bio-breeding rat

31 March 2020

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Glucose transporters in rat peripheral nerve: Paranodal expression of GLUT1 and GLUT3

31 March 2020

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Molecular organization of the nodal region is not altered in spontaneously diabetic BB-Wistar rats

31 March 2020

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Role of the Schwann cell in diabetic neuropathy

31 March 2020

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Regenerative failure of diabetic nerves bridging transection injuries

31 March 2020

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Excitotoxic mechanisms in stroke: an update of concepts and treatment strategies

31 March 2020

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Activity-dependent regulation of energy metabolism by astrocytes: an update

31 March 2020

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Regulation of aldose reductase expression in rat astrocytes in culture

31 March 2020

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Metabolic pathways for glucose in astrocytes.

31 March 2020

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Glutathione peroxidase-catalase cooperativity is required for resistance to hydrogen peroxide by mature rat oligodendrocytes.

31 March 2020

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Diabetes mellitus and stroke

31 March 2020

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Diabetes and stroke: part one--risk factors and pathophysiology

31 March 2020

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Diabetes and stroke: part two--treating diabetes and stress hyperglycemia in hospitalized stroke patients

31 March 2020

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The role of hyperglycemia in acute ischemic stroke

31 March 2020

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Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes

31 March 2020

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Variations in motor conduction velocity produced by acute changes of the metabolic state in diabetic patients

31 March 2020

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Reversal, by treatment with an aldose reductase inhibitor, of impaired axonal transport and motor nerve conduction velocity in experimental diabetes mellitus

31 March 2020

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Prevention and reversal of defective axonal transport and motor nerve conduction velocity in rats with experimental diabetes by treatment with the aldose reductase inhibitor Sorbinil

31 March 2020

1 reference

Peripheral nerves in early experimental diabetes: expansion of the endoneurial space as a cause of increased water content

31 March 2020

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Early and preventable changes of peripheral nerve structure and function in insulin-deficient diabetic rats

31 March 2020

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Aldose Reductase Inhibitors: The End of an Era or the Need for Different Trial Designs?

31 March 2020

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Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group

31 March 2020

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Diabetic neuropathy--a review

31 March 2020

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The pathogenesis and management of painful diabetic neuropathy: a review

31 March 2020

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Continuous subcutaneous insulin infusion in the management of painful diabetic neuropathy

31 March 2020

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The natural history of acute painful neuropathy in diabetes mellitus

31 March 2020

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Peripheral nerve function in patients with painful diabetic neuropathy treated with continuous subcutaneous insulin infusion

31 March 2020

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Mechanism of pain in diabetic peripheral neuropathy. Effect of glucose on pain perception in humans

31 March 2020

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Glycemic control of pain threshold in diabetic and control rats

31 March 2020

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The relationship between blood glucose excursions and painful diabetic peripheral neuropathy: a pilot study

31 March 2020

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Mechanical hyperalgesia in rats with chronic perfusion of lumbar dorsal root ganglion with hyperglycemic solution

31 March 2020

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Mechanical hyperalgesia in rat models of systemic and local hyperglycemia.

31 March 2020

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Diabetes-induced mechanical hyperalgesia involves spinal mitogen-activated protein kinase activation in neurons and microglia via N-methyl-D-aspartate-dependent mechanisms

31 March 2020

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Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model

31 March 2020

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Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine

31 March 2020

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Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain

31 March 2020

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Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat.

31 March 2020

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A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats

31 March 2020

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Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats

31 March 2020

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Potential mechanisms of neuropathic pain in diabetes

31 March 2020

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Rapid onset pain induced by intravenous streptozotocin in the rat

31 March 2020

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Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats

31 March 2020

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Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: modulation by nitecapone, a COMT inhibitor with antioxidant properties

31 March 2020

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Upregulation of mRNAs coding for AMPA and NMDA receptor subunits and metabotropic glutamate receptors in the dorsal horn of the spinal cord in a rat model of diabetes mellitus

31 March 2020

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p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

31 March 2020

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Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

31 March 2020

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Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing

31 March 2020

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Pathogenesis of spinally mediated hyperalgesia in diabetes.

31 March 2020

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Axonal transport of labeled protein and regeneration rate in nerves of streptozocin-diabetic rats

31 March 2020

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Impaired nerve regeneration in streptozotocin-diabetic rats. Effects of treatment with an aldose reductase inhibitor

31 March 2020

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The regenerative deficit of peripheral nerves in experimental diabetes: its extent, timing and possible mechanisms

31 March 2020

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Myelinated nerve fibre regeneration in diabetic sensory polyneuropathy: correlation with type of diabetes

31 March 2020

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Quantitative screening of protein biomarkers of early glycation, advanced glycation, oxidation and nitrosation in cellular and extracellular proteins by tandem mass spectrometry multiple reaction monitoring

31 March 2020

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Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

31 March 2020

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Glycation in diabetic neuropathy: characteristics, consequences, causes, and therapeutic options

31 March 2020

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Glycation of rat sciatic nerve tubulin in experimental diabetes mellitus

31 March 2020

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Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

31 March 2020

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Structural and functional changes of laminin and type IV collagen after nonenzymatic glycation

31 March 2020

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Advanced glycation endproducts interefere with integrin-mediated osteoblastic attachment to a type-I collagen matrix

31 March 2020

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The effect of advanced glycation end-product formation upon cell-matrix interactions

31 March 2020

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Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways

31 March 2020

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Nonenzymatic glycosylation of laminin and the laminin peptide CIKVAVS inhibits neurite outgrowth

31 March 2020

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Effects of nonenzymatic glycosylation of extracellular matrix components on cell survival and sensory neurite extension in cell culture

31 March 2020

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The effect of non-enzymatic glycation of extracellular matrix proteins on axonal regeneration in vitro

31 March 2020

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Biochemistry and molecular cell biology of diabetic complications

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRN2294

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Dimensions Publication ID

17 August 2017

1008278009

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