(Q36760031)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

review article

1 reference

title

A tumor suppressor and oncogene: the WT1 story (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Yang L

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Han Y

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Minden MD

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

1 reference

15 March 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

868-876

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17361230%20AND%20SRC:MED&resulttype=core&format=json

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1

27 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

The LIM-only coactivator FHL2 modulates WT1 transcriptional activity during gonadal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

Identification of WTAP, a novel Wilms' tumour 1-associating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms' tumour: connecting tumorigenesis and organ development in the kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Alternative splicing and genomic structure of the Wilms tumor gene WT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The transcriptional effect of WT1 is modulated by choice of expression vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Alternative splicing of Wilms' tumor suppressor protein modulates DNA binding activity through isoform-specific DNA-induced conformational changes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Transcriptional activation of c-myc proto-oncogene by WT1 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t(14;18) Lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

A clinical overview of WT1 gene mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Evidence that WT1 mutations in Denys — Drash syndrome patients may act in a dominant-negative fashion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

DNA binding capacity of the WT1 protein is abolished by Denys—Drash syndrome WT1 point mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +/-KTS splice isoforms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1 induces apoptosis through transcriptional regulation of the proapoptotic Bcl-2 family member Bak.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Role of the WT1 tumor suppressor in murine hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wt1 is not essential for hematopoiesis in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Prognostically useful gene-expression profiles in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1 gene expression: an excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukaemia patients - results from a single-centre study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The Wilms' tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The coexpression of the apoptosis-related genes bcl-2 and wt1 in predicting survival in adult acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms' tumor gene product WT1 arrests macrophage differentiation of HL-60 cells through its zinc-finger domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Downregulation of Wilms' tumor gene (WT1) is not a prerequisite for erythroid or megakaryocytic differentiation of the leukemic cell line K562.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1-p53 interactions in insulin-like growth factor-I receptor gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

N-terminally truncated WT1 protein with oncogenic properties overexpressed in leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Inhibition of the DNA-binding and transcriptional repression activity of the Wilms' tumor gene product, WT1, by cAMP-dependent protein kinase-mediated phosphorylation of Ser-365 and Ser-393 in the zinc finger domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

p53 alterations in myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

FGFR1 and WT1 are markers of human prostate cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Prognostic significance of quantitative analysis of WT1 gene transcripts by competitive reverse transcription polymerase chain reaction in acute leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Detection of the WT1 transcript by RT-PCR in complete remission has no prognostic relevance in de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Cancer immunotherapy targeting Wilms' tumor gene WT1 product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms' tumor 1 mutation accumulated during therapy in acute myeloid leukemia: biological and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Repression of promoters for the mouse insulin-like growth factor II-encoding gene (Igf-2) by products of the Wilms' tumour suppressor gene wt1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Differential Effects of Wilms Tumor WT1 Splice Variants on the Insulin Receptor Promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Repression of the c-myb gene by WT1 protein in T and B cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Cyclin E is a target of WT1 transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Truncation of WT1 results in downregulation of cyclin G1 and IGFBP-4 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Ornithine decarboxylase is a transcriptional target of tumor suppressor WT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Regulation of ornithine decarboxylase gene expression by the Wilms' tumor suppressor WT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

E-cadherin is a WT1 target gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

The Wilms' tumor gene product represses the transcription of thrombospondin 1 in response to overexpression of c-Jun

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene W T1 in primary astrocytic tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Immunohistochemical detection of WT1 protein in a variety of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene WT1 in head and neck squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1 mutation in malignant mesothelioma and WT1 immunoreactivity in relation to p53 and growth factor receptor expression, cell-type transition, and prognosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Expression and mutation analysis of the Wilms' tumor 1 gene in human neural tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms Tumor Gene (WT1) and p53 expression in endometrial carcinomas: a study of 130 cases using a tissue microarray

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Expression of Wilms tumor gene (WT1) in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Constitutive expression of the Wilms tumor suppressor gene (WT1) in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms' tumor 1 and signal transducers and activators of transcription 3 synergistically promote cell proliferation: a possible mechanism in sporadic Wilms' tumor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

A functional interaction with CBP contributes to transcriptional activation by the Wilms tumor suppressor WT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Physical and functional interaction between WT1 and p53 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Physical interaction between Wilms tumor 1 and p73 proteins modulates their functions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

E1B 55K sequesters WT1 along with p53 within a cytoplasmic body in adenovirus-transformed kidney cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021

Antagonism of WT1 activity by protein self-association.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404624

7 January 2021