(Q36674580)

English

Novel Interaction Mechanism of a Domain Antibody-based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency than Ranibizumab and Bevacizumab and Improved Capacity over Aflibercept

scientific article published on 4 January 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Novel Interaction Mechanism of a Domain Antibody-based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency than Ranibizumab and Bevacizumab and Improved Capacity over Aflibercept (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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1 reference

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author name string

Adam Walker

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Chun-Wa Chung

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Margarete Neu

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Manish Burman

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Thil Batuwangala

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Gavin Jones

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Chi-Man Tang

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Michael Steward

8

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Michael Mullin

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Nadia Tournier

10

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Alan Lewis

11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Justyna Korczynska

12

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Vicky Chung

13

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ian Catchpole

14

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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publication date

4 January 2016

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Europe PubMed Central

PMC publication ID

15 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

15 August 2017

291

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Europe PubMed Central

PMC publication ID

15 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

5500-5511

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Stress selections on domain antibodies: 'what doesn't kill you makes you stronger'.

1 reference

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Comparison of binding characteristics and in vitro activities of three inhibitors of vascular endothelial growth factor A.

1 reference

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Ocular delivery of macromolecules

1 reference

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Intravitreal aflibercept (Eylea(®)): a review of its use in patients with macular oedema secondary to central retinal vein occlusion

1 reference

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Potent anti-angiogenesis and anti-tumor activity of a novel human anti-VEGF antibody, MIL60.

1 reference

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1 reference

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Isotype and glycoform selection for antibody therapeutics

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Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

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30 September 2017

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1 reference

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VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

1 reference

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Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration

1 reference

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Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.

1 reference

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Scaling and assessment of data quality

1 reference

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Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

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Coot: model-building tools for molecular graphics

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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30 September 2017

The CCP4 suite: programs for protein crystallography

1 reference

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30 September 2017

Domain antibodies: proteins for therapy

1 reference

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30 September 2017

VEGF-Trap: a VEGF blocker with potent antitumor effects

1 reference

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IgG-Fc receptors and the clinical relevance of their polymorphisms

1 reference

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Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

1 reference

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30 September 2017

Solution structure of the heparin-binding domain of vascular endothelial growth factor

1 reference

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30 September 2017

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: multiple copy flexibility and receptor binding

1 reference

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Fc receptors and their interactions with immunoglobulins

1 reference

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Cloning and characterization of a novel human gene related to vascular endothelial growth factor

1 reference

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Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer

1 reference

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High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

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Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

1 reference

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30 September 2017

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

1 reference

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28 June 2018

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Comparative antiproliferative and cytotoxic profile of bevacizumab (Avastin), pegaptanib (Macugen) and ranibizumab (Lucentis) on different ocular cells

1 reference

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21 January 2018

19. Targeted nanoparticles for smarter cancer therapy: Original research article: Folate receptor targeted biodegradable polymeric doxorubicin micelles, 2004

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-vascular endothelial growth factor treatment for eye diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/26728464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M115.691162

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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