(Q36573040)

15 August 2017

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53 (English)

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.94.18.9648

neoplastic gene expression regulation

13 November 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

13 November 2024

author name string

M. M. Sugrue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

13 November 2024

D. Y. Shin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

13 November 2024

S. W. Lee

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

13 November 2024

S. A. Aaronson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

13 November 2024

language of work or name

English

0 references

publication date

1 September 1997

1 reference

PMC publication ID

23243

15 August 2017

2 September 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9275177

13 November 2024

number of pages

6

1 reference

full work available at URL

inferred from page(s)

https://europepmc.org/articles/pmc23243?pdf=render

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

https://europepmc.org/articles/PMC23243

13 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

https://europepmc.org/articles/PMC23243?pdf=render

13 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9275177

https://pnas.org/doi/pdf/10.1073/pnas.94.18.9648

13 November 2024

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.94.18.9648

Proceedings of the National Academy of Sciences of the United States of America

13 November 2024

published in

1 reference

15 August 2017

94

1 reference

15 August 2017

18

1 reference

15 August 2017

9648-9653

1 reference

The serial cultivation of human diploid cell strains

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

p53, the cellular gatekeeper for growth and division

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Replicative senescence: implications for in vivo aging and tumor suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

mdm2 expression is induced by wild type p53 activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

The p53-mdm-2 autoregulatory feedback loop

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

WAF1, a potential mediator of p53 tumor suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

A gene involved in control of human cellular senescence on human chromosome 1q

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Chromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Apoptosis in the pathogenesis and treatment of disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Mechanisms and genes of cellular suicide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Human bladder carcinoma cell lines as indicators of oncogenic change relevant to urothelial neoplastic progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Increased activity of p53 in senescing fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Mechanism of activation of a human oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Localization of gene for human p53 tumour antigen to band 17p13.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Mutations in p53 as potential molecular markers for human breast cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

p53 mutations in human cancers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Cancer. p53, guardian of the genome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Increased p53 Protein Associated with Aging in Human Diploid Fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Genetic determinants of p53-induced apoptosis and growth arrest

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Proliferative capacity and DNA content of aging human diploid cells in culture: a cytophotometric and autoradiographic analysis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Escape from senescence in human diploid fibroblasts induced directly by mutant p53.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23243

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

21 September 2018

1 reference

12 December 2020

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice

1 reference

12 December 2020

Enhanced proliferative potential in culture of cells from p53-deficient mice

1 reference

12 December 2020

Functional interaction of wild-type and mutant p53 transfected into human tumor cell lines carrying activated ras genes

1 reference

12 December 2020

Replicative senescence and cell death

1 reference

12 December 2020

20

5

444

Neumann J M

1987

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.94.18.9648

13 November 2024

Identifiers

1 reference

15 August 2017

0 references

1 reference

PMC publication ID

23243

15 August 2017

1 reference

PMC publication ID

23243