(Q36546467)

14 August 2017

1 reference

title

Apolipoprotein (apo) E4 and Alzheimer's disease: unique conformational and biophysical properties of apoE4 can modulate neuropathology (English)

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14 August 2017

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R W Mahley

1

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14 August 2017

Y Huang

series ordinal

2

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14 August 2017

publication date

1 January 2006

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Acta neurologica Scandinavica. Supplementum

14 August 2017

published in

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14 August 2017

volume

185

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14 August 2017

page(s)

8-14

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Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

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Apolipoprotein E alleles as risk factors in Alzheimer's disease

21 January 2018

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Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury

21 January 2018

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Association of apolipoprotein E polymorphism with outcome after head injury.

21 January 2018

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APOE genotype as a risk factor for ischemic cerebrovascular disease: a meta-analysis

21 January 2018

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Apolipoprotein E epsilon 4 is associated with rapid progression of multiple sclerosis

21 January 2018

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

21 January 2018

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Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

21 January 2018

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Clearing the brain's amyloid cobwebs

21 January 2018

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

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Apolipoprotein E: far more than a lipid transport protein

21 January 2018

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Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond

21 January 2018

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

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Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

21 January 2018

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Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

21 January 2018

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Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

21 January 2018

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Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

21 January 2018

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Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

21 January 2018

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Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

21 January 2018

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Apolipoprotein E and cognitive performance

21 January 2018

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Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain

21 January 2018

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Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

21 January 2018

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The structural basis of protein folding and its links with human disease

21 January 2018

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Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins

21 January 2018

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Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells

21 January 2018

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Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

21 January 2018

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Regionally specific neuronal expression of human APOE gene in transgenic mice

21 January 2018

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Specific regional transcription of apolipoprotein E in human brain neurons

21 January 2018

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Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice

21 January 2018

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Increased expression of neuronal apolipoprotein E in human brain with cerebral infarction.

21 January 2018

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Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

21 January 2018

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The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review

21 January 2018

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Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease

21 January 2018

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Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

21 January 2018

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Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease

21 January 2018

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Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease

21 January 2018

1 reference

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Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

21 January 2018

1 reference

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Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner

21 January 2018

1 reference

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Oxidative protein damage in cells engaged in beta-amyloidosis is related to apoE genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

21 January 2018

1 reference

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Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

21 January 2018

1 reference

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Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice

21 January 2018

1 reference

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Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

A minimally lipidated form of cell-derived apolipoprotein E exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid beta-peptide deposition in homozygous APP(V717F) transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2006.00679.X

10.1111/J.1600-0404.2006.00679.X

21 January 2018

Identifiers

DOI

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1 reference