(Q36544440)

14 August 2017

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title

Translational control of gene expression during hypoxia (English)

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14 August 2017

0 references

3

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14 August 2017

Marianne Koritzinsky

2

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Twan van den Beucken

series ordinal

1

object named as

Twan van den Beucken

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14 August 2017

publication date

1 July 2006

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Cancer Biology and Therapy

14 August 2017

published in

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14 August 2017

volume

5

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14 August 2017

issue

7

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14 August 2017

page(s)

749-755

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A second look at cellular mRNA sequences said to function as internal ribosome entry sites

14 August 2017

cites work

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions

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7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Activating transcription factor 4 is translationally regulated by hypoxic stress

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

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7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies

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7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Enhancement of IRES-Mediated Translation of the c-myc and BiP mRNAs by the Poly(A) Tail Is Independent of Intact eIF4G and PABP

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

The power of the 3' UTR: translational control and development

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7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Targeting HIF-1 for cancer therapy

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Hypoxia and drug resistance

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Translational control in development: a perspective

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Isolation of translationally controlled mRNAs by differential screening.

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

The polypyrimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

IRESdb: the Internal Ribosome Entry Site database

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Control of eukaryotic protein synthesis by upstream open reading frames in the 5'-untranslated region of an mRNA

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Downstream control of upstream open reading frames

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Exploiting tumour hypoxia in cancer treatment

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Internal initiation of translation mediated by the 5′ leader of a cellular mRNA

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Genome-wide analysis of transcript abundance and translation in Arabidopsis seedlings subjected to oxygen deprivation

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

The LKB1 tumor suppressor negatively regulates mTOR signaling

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Translation of Vascular Endothelial Growth Factor mRNA by Internal Ribosome Entry: Implications for Translation under Hypoxia

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Evolutionary conservation suggests a regulatory function of AUG triplets in 5'-UTRs of eukaryotic genes

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Translational control in stress and apoptosis

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Assessing IRES activity in the HIF-1alpha and other cellular 5' UTRs

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Statistical analysis of the 5' untranslated region of human mRNA using "Oligo-Capped" cDNA libraries

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Translational control by an upstream open reading frame in the HER-2/neu transcript

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Hypoxia-induced energy stress regulates mRNA translation and cell growth

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Internal ribosome entry sites in eukaryotic mRNA molecules

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Highly conserved RNA sequences that are sensors of environmental stress

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Derepression of the Her-2 uORF is mediated by a novel post-transcriptional control mechanism in cancer cells

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

1 reference

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

The hypoxic proteome is influenced by gene-specific changes in mRNA translation

2 references

7 July 2024

https://opencitations.net/index/api/v1/references/10.4161/CBT.5.7.2972

7 July 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.RADONC.2005.06.036

Identifiers

DOI

10.4161/CBT.5.7.2972

1 reference

14 August 2017

1 reference