(Q36504889)

English

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).

scientific article published on 13 June 2006

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

1 reference

Europe PubMed Central

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease). (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

0 references

Alzheimer's disease

0 references

1

object named as

Roses AD

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

2

object named as

Saunders AM

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

author name string

Huang Y

3

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Strum J

4

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Weisgraber KH

5

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Mahley RW

6

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

publication date

13 June 2006

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

The Pharmacogenomics Journal

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

10-28

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Tau gene mutation K257T causes a tauopathy similar to Pick's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Cerebral glucose metabolism in patients with AD and different APOE genotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

The effect of APOE epsilon4 allele on cerebral glucose metabolism in AD is a function of age at onset

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

APOE genotype is a major predictor of long-term progression of disability in MS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Apolipoprotein E epsilon 4 is associated with rapid progression of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Apolipoprotein E isoforms increase intracellular Ca2+ differentially through a omega-agatoxin IVa-sensitive Ca2+-channel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

MCI conversion to dementia and the APOE genotype: a prediction study with FDG-PET.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Commentary on "Perspective on a pathogenesis and treatment of Alzheimer's disease." Apolipoprotein E and the mitochondrial metabolic hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

21 January 2018

Pharmacogenetics and drug development: the path to safer and more effective drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacogenetics and the practice of medicine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Shaking the tree: mapping complex disease genes with linkage disequilibrium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E alleles as risk factors in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer diseases: a model of gene mutations and susceptibility polymorphisms for complex psychiatric diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Senile dementia of the Alzheimer type

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Diagnosis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Frontotemporal dementia with novel tau pathology and a Glu342Valtau mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibrillogenesis of tau: insights from tau missense mutations in FTDP-17.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Tau gene mutation in familial progressive subcortical gliosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid double trouble.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Early regional cerebral glucose hypometabolism in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-wide screening for gene function using RNAi in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Disease-specific target selection: a critical first step down the right road

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Perspective on a pathogenesis and treatment of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

APOE related alterations in cerebral activation even at college age.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial dysfunction and its role in motor neuron degeneration in ALS.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial function in apoptotic neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Dendritic pathology of granule cells in Alzheimer's disease is unrelated to neuritic plaques.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacogenetics goes genomic

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of genomic signatures in therapeutics development in oncology and other diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Breast cancer genetics: what we know and what we need

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Genome-based pharmacogenetics and the pharmaceutical industry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a pharmacogenetic effect by linkage disequilibrium mapping

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

UDP-glucuronosyltransferases and clinical drug-drug interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical pharmacogenomics and transcriptional profiling in early phase oncology clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacogenetics-based new therapeutic concepts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacogenetics-based therapeutic recommendations — ready for clinical practice?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: far more than a lipid transport protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: structure-function relationships

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of apolipoprotein E genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Familial dementia with lewy bodies: a clinical and neuropathological study of 2 families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

APOE: a potential marker of disease progression in ALS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid beta-protein, APOE genotype and head injury

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E expression by neurons surviving excitotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E Uptake and Low-Density Lipoprotein Receptor-Related Protein Expression by the NTera2/D1 Cell Line: A Cell Culture Model of Relevance for Late-Onset Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E and cholesterol affect neuronal calcium signalling: the possible relationship to beta-amyloid neurotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid elevation of neuronal cytoplasmic calcium by apolipoprotein E peptide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related memory decline: current concepts and future directions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: implications for brain reserve

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain metabolic decreases related to the dose of the ApoE e4 allele in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Age and ApoE genotype interaction in Alzheimer's disease: an FDG-PET study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate decreases mitochondrial size and movement in primary forebrain neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoskeletal dynamics in dendritic spines: direct modulation by glutamate receptors?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure and composition of CA3-->CA1 axons in rat hippocampal slices: implications for presynaptic connectivity and compartmentalization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial trafficking in neurons: a key variable in neurodegeneration?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E and Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular uptake of the tat protein from human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E-binding proteins isolated from dog and human liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Axonal mitochondrial transport and potential are correlated

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial dysfunction and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial diseases in man and mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial DNA haplotype predicts deafness risk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial enzymes in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Frontal lobe dysfunction in progressive supranuclear palsy: evidence for oxidative stress and mitochondrial impairment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Enzyme activities in quadriceps femoris muscle of obese diabetic male patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mild impairments in cognition in patients with type 2 diabetes mellitus: the use of the concepts MCI and CIND.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin and neurodegenerative disease: shared and specific mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Improving metabolic control leads to better working memory in adults with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative imbalance in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Differentiated Alzheimer's disease transmitochondrial cybrid cell lines exhibit reduced organelle movement

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Are mitochondria critical in the pathogenesis of Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Gradual alteration of mitochondrial structure and function by beta-amyloids: importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial aging and dysfunction in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Binding of gelsolin, a secretory protein, to amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

125I-labeled ApoE binds competitively to β(1-40) fibrils with pathological chaperone proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of polymorphism on the lipid interaction of human apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Glycated hemoglobin and lipid peroxidation in erythrocytes of diabetic patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Opinion: anticipating change in drug development: the emerging era of translational medicine and therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Translational medicine and the National Institutes of Health road map: steep grades and tortuous curves

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic diversity and new therapeutic concepts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500397

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.TPJ.6500397

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36504889&oldid=2269663009"