(Q36363653)

13 August 2017

Mutational analysis of an autoantibody: differential binding and pathogenicity (English)

1 reference

13 August 2017

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1 reference

J B Katz

1

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13 August 2017

W Limpanasithikul

series ordinal

2

1 reference

13 August 2017

B Diamond

series ordinal

3

1 reference

13 August 2017

language of work or name

English

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publication date

1 September 1994

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Journal of Experimental Medicine

13 August 2017

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13 August 2017

180

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13 August 2017

3

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13 August 2017

925-932

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Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA sequences in whole cell lysates

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Different interactions used by Cro repressor in specific and nonspecific DNA binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Variable region framework differences result in decreased or increased affinity of variant anti-digoxin antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

The invariant tryptophan in an H chain V region is not essential to antibody binding

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Recurrent somatic mutations in mouse antibodies to p-azophenylarsonate increase affinity for hapten

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Structural correlates of high antibody affinity: three engineered amino acid substitutions can increase the affinity of an anti-p-azophenylarsonate antibody 200-fold

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

A novel class of anti-DNA antibodies identified in BALB/c mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

An autoantibody to single-stranded DNA: Comparison of the three-dimensional structures of the unliganded fab and a deoxynucleotide-fab complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Sequence-specific recognition of double helical nucleic acids by proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Comparison of pathogenic and non-pathogenic murine antibodies to DNA: antigen binding and structural characteristics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Interclonal and intraclonal diversity among anti-DNA antibodies from an (NZB x NZW)F1 mouse

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2191646

Mutations in immunoglobulin-producing mouse myeloma cells

28 June 2018

1 reference

12 December 2020

Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus. Comparison of antibodies in serum and renal eluates

1 reference

12 December 2020

Correlation of DNA-anti-DNA association rates with clinical activity in systemic lupus erythematosus (SLE)

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12 December 2020

Clinical significance of anti-double-stranded DNA antibodies detected by a solid phase enzyme immunoassay

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12 December 2020

Direct measurement of antibody affinity distribution by hapten-inhibition enzyme immunoassay

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12 December 2020

Molecular events during maturation of the immune response to oxazolone

1 reference

12 December 2020

The role of clonal selection and somatic mutation in autoimmunity

1 reference

12 December 2020

Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.180.3.925

1 reference

13 August 2017

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13 August 2017

PubMed publication ID

8064241

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