(Q36350066)

13 August 2017

Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy (English)

1 reference

13 August 2017

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy (English)

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

14 March 2024

author name string

Tetsuo Shioi

2

1 reference

13 August 2017

Li Zhang

3

1 reference

13 August 2017

Oleg Tarnavski

4

1 reference

13 August 2017

Seigo Izumo

7

1 reference

13 August 2017

Julie R. McMullen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

14 March 2024

Megan C. Sherwood

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

14 March 2024

Peter M. Kang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

14 March 2024

language of work or name

English

0 references

publication date

24 September 2003

1 reference

13 August 2017

6

1 reference

full work available at URL

inferred from page(s)

https://europepmc.org/articles/pmc218762?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

https://europepmc.org/articles/PMC218762

14 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

https://europepmc.org/articles/PMC218762?pdf=render

14 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

https://doi.org/10.1073/pnas.1934654100

14 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507992

https://pnas.org/doi/pdf/10.1073/pnas.1934654100

14 March 2024

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

Proceedings of the National Academy of Sciences of the United States of America

14 March 2024

published in

1 reference

13 August 2017

100

1 reference

13 August 2017

21

1 reference

13 August 2017

12355-12360

1 reference

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Calcineurin and cardiac hypertrophy: where have we been? Where are we going?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Growth hormone and the heart

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

L-arginine enhances aerobic exercise capacity in association with augmented nitric oxide production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Therapeutic options in minimizing left ventricular hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Expression of protein kinase C beta in the heart causes hypertrophy in adult mice and sudden death in neonates.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Transgenic Gαq overexpression induces cardiac contractile failure in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Signalling through the lipid products of phosphoinositide-3-OH kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

The cardiac hypertrophic responses to pathologic and physiologic loads

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Rapamycin attenuates load-induced cardiac hypertrophy in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Converging pathways and principles in heart development and disease: CV@CSH.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Increased cardiac sympathetic activity and insulin-like growth factor-I formation are associated with physiological hypertrophy in athletes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Exercise and mechanical loading increase periosteal bone formation and whole bone strength in C57BL/6J mice but not in C3H/Hej mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=218762

Cardiotrophic Effects of Protein Kinase C : Analysis by In Vivo Modulation of PKC Translocation

22 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934654100

Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934654100

The role of the Grb2–p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934654100

Effect of growth hormone administration and treadmill exercise on serum and skeletal IGF-I in rats

21 January 2018

1 reference

12 December 2020

Alterations in gene expression in the rat heart after chronic pathological and physiological loads

1 reference

12 December 2020

Cardiac adaptations to chronic exercise in mice

1 reference

12 December 2020

Angiotensin receptor 1 blockade does not prevent physiological cardiac hypertrophy in the adult rat

1 reference

12 December 2020

Epsilon protein kinase C in pathological myocardial hypertrophy. Analysis by combined transgenic expression of translocation modifiers and Galphaq

1 reference

12 December 2020

Impact of different sports and training on cardiac structure and function

1 reference

12 December 2020

Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

1 reference

12 December 2020

Serum levels of total and free IGF-I and IGFBP-3 are increased and maintained in long-term training

1 reference

12 December 2020

Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease

1 reference

12 December 2020

Cardiac overexpression of a G(q) inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH(2)-terminal kinase activity in in vivo pressure overload

1 reference

12 December 2020

Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes

1 reference

12 December 2020

Echocardiographic assessment of LV hypertrophy and function in aortic-banded mice: necropsy validation

1 reference

12 December 2020

Progression of dystrophic features and activation of mitogen-activated protein kinases and calcineurin by physical exercise, in hearts of mdx mice

1 reference

12 December 2020

Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy

1 reference

12 December 2020

Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-gamma

6

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

The economics of heart transplantation

14 March 2024

7

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

Potential assays for sperm capacitation in mammals

14 March 2024

9

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

Pressure Overload Induces Severe Hypertrophy in Mice Treated With Cyclosporine, an Inhibitor of Calcineurin

14 March 2024

18

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

Journal of Biological Chemistry

14 March 2024

45

86

29927

2000

1 reference

https://api.crossref.org/works/10.1073/PNAS.1934654100

14 March 2024

Identifiers

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference