(Q36146947)

12 August 2017

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title

Autophagy: dual roles in life and death? (English)

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12 August 2017

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Eric H Baehrecke

1

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12 August 2017

publication date

1 June 2005

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Nature Reviews Molecular Cell Biology

12 August 2017

published in

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12 August 2017

volume

6

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12 August 2017

issue

6

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12 August 2017

page(s)

505-510

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Size control in animal development

12 August 2017

cites work

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21 January 2018

The Hallmarks of Cancer

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How death shapes life during development

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Four deaths and a funeral: from caspases to alternative mechanisms.

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Autophagy as a regulated pathway of cellular degradation

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Autophagy in the eukaryotic cell

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Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

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21 January 2018

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Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

21 January 2018

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Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

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Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

21 January 2018

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Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway

21 January 2018

1 reference

A Unified Nomenclature for Yeast Autophagy-Related Genes

21 January 2018

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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

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Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

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Role and regulation of starvation-induced autophagy in the Drosophila fat body

21 January 2018

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The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

1 reference

Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway

21 January 2018

1 reference

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

1 reference

The molecular machinery of autophagy: unanswered questions

21 January 2018

1 reference

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

21 January 2018

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Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

21 January 2018

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The phosphoinositide 3-kinase pathway

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Autophagy: a barrier or an adaptive response to cancer.

21 January 2018

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PI3K/Akt and apoptosis: size matters

21 January 2018

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Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

21 January 2018

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Caspase-independent cell death in T lymphocytes

21 January 2018

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Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

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Caspase-independent cell killing by Fas-associated protein with death domain

21 January 2018

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Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

21 January 2018

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

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Necrotic death pathway in Fas receptor signaling

21 January 2018

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Caspases function in autophagic programmed cell death in Drosophila

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Steroid regulation of midgut cell death during Drosophila development

21 January 2018

1 reference

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro

21 January 2018

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Inhibition of macroautophagy triggers apoptosis

21 January 2018

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Genome-wide analyses of steroid- and radiation-triggered programmed cell death in Drosophila.

21 January 2018

1 reference

Deadly encounter: ubiquitin meets apoptosis

21 January 2018

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Ald6p is a preferred target for autophagy in yeast, Saccharomyces cerevisiae

21 January 2018

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DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

21 January 2018

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Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster

21 January 2018

1 reference

HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death

21 January 2018

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

1 reference

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

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Interdigital cell death can occur through a necrotic and caspase-independent pathway.

21 January 2018

1 reference

Autophagy in health and disease: a double-edged sword

21 January 2018

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High frequency of mutations of the PIK3CA gene in human cancers

21 January 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

Caspase Activity and a Specific Cytochrome C Are Required for Sperm Differentiation in Drosophila

21 January 2018

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Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization

21 January 2018

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

21 January 2018

1 reference

Cell biology: regulated self-cannibalism.

21 January 2018

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A matter of life and death

21 January 2018

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The morphology of various types of cell death in prenatal tissues

31 March 2020

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Programmed cell death of developing mammalian neurons after genetic deletion of caspases.

31 March 2020

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Autophagy in human tumors: cell survival or death?

31 March 2020

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

31 March 2020

1 reference

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRM1666

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12 August 2017

1 reference