(Q36011649)

11 August 2017

1 reference

title

Assembly and function of RNA silencing complexes (English)

1 reference

11 August 2017

Erik J Sontheimer

1

0 references

publication date

1 February 2005

1 reference

Nature Reviews Molecular Cell Biology

11 August 2017

published in

1 reference

11 August 2017

volume

6

1 reference

11 August 2017

issue

2

1 reference

11 August 2017

page(s)

127-138

1 reference

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

11 August 2017

cites work

1 reference

Planting the seeds of a new paradigm

31 March 2020

1 reference

Quelling in Neurospora crassa

31 March 2020

1 reference

Killing the messenger: short RNAs that silence gene expression

31 March 2020

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

31 March 2020

1 reference

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

31 March 2020

1 reference

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

31 March 2020

1 reference

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

31 March 2020

1 reference

A biochemical framework for RNA silencing in plants

31 March 2020

1 reference

The genetics of RNA silencing

31 March 2020

1 reference

A species of small antisense RNA in posttranscriptional gene silencing in plants

31 March 2020

1 reference

RNA interference is mediated by 21- and 22-nucleotide RNAs

31 March 2020

1 reference

Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos.

31 March 2020

1 reference

Role for a bidentate ribonuclease in the initiation step of RNA interference

31 March 2020

1 reference

Argonaute2, a link between genetic and biochemical analyses of RNAi

31 March 2020

1 reference

ATP requirements and small interfering RNA structure in the RNA interference pathway

31 March 2020

1 reference

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

31 March 2020

1 reference

A microRNA in a multiple-turnover RNAi enzyme complex

31 March 2020

1 reference

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

31 March 2020

1 reference

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

31 March 2020

1 reference

The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

31 March 2020

1 reference

Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer

31 March 2020

1 reference

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

31 March 2020

1 reference

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

31 March 2020

1 reference

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

31 March 2020

1 reference

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

31 March 2020

1 reference

Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors

31 March 2020

1 reference

Argonaute2 is the catalytic engine of mammalian RNAi

31 March 2020

1 reference

Synthetic shRNAs as potent RNAi triggers

31 March 2020

1 reference

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

31 March 2020

1 reference

RISC assembly defects in the Drosophila RNAi mutant armitage.

31 March 2020

1 reference

A protein sensor for siRNA asymmetry

31 March 2020

1 reference

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

31 March 2020

1 reference

microRNAs: runts of the genome assert themselves

31 March 2020

1 reference

MicroRNAs: genomics, biogenesis, mechanism, and function

31 March 2020

1 reference

MicroRNAs: small RNAs with a big role in gene regulation

31 March 2020

1 reference

Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA

31 March 2020

1 reference

The role of RNA interference in heterochromatic silencing

31 March 2020

1 reference

RNAi-mediated targeting of heterochromatin by the RITS complex

31 March 2020

1 reference

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

31 March 2020

1 reference

DEAD-box proteins: the driving forces behind RNA metabolism

31 March 2020

1 reference

RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E.

31 March 2020

1 reference

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

31 March 2020

1 reference

Functional siRNAs and miRNAs Exhibit Strand Bias

31 March 2020

1 reference

Asymmetry in the assembly of the RNAi enzyme complex

31 March 2020

1 reference

Rational siRNA design for RNA interference

31 March 2020

1 reference

Improving the efficiency of RNA interference in mammals

31 March 2020

1 reference

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

31 March 2020

1 reference

Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain

31 March 2020

1 reference

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

31 March 2020

1 reference

Single processing center models for human Dicer and bacterial RNase III

31 March 2020

1 reference

Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs

31 March 2020

1 reference

Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity

31 March 2020

1 reference

31 March 2020

1 reference

A micrococcal nuclease homologue in RNAi effector complexes

31 March 2020

1 reference

RISC is a 5' phosphomonoester-producing RNA endonuclease

31 March 2020

1 reference

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

31 March 2020

1 reference

The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

31 March 2020

1 reference

Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

31 March 2020

1 reference

Crystal structure of Argonaute and its implications for RISC slicer activity

31 March 2020

1 reference

The RNA-induced silencing complex is a Mg2+-dependent endonuclease.

31 March 2020

1 reference

An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei

31 March 2020

1 reference

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

31 March 2020

1 reference

Kinetic analysis of the RNAi enzyme complex

31 March 2020

1 reference

Sequence-specific inhibition of small RNA function

31 March 2020

1 reference

The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction

31 March 2020

1 reference

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

31 March 2020

1 reference

Unlocking the potential of the human genome with RNA interference

31 March 2020

1 reference

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

31 March 2020

1 reference

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

31 March 2020

1 reference

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

31 March 2020

1 reference

MicroRNA-directed cleavage of HOXB8 mRNA

31 March 2020

1 reference

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

31 March 2020

1 reference

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

31 March 2020

1 reference

Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena

31 March 2020

1 reference

RNA silencing genes control de novo DNA methylation

31 March 2020

1 reference

Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery

31 March 2020

1 reference

31 March 2020

1 reference

Dicer is essential for formation of the heterochromatin structure in vertebrate cells

31 March 2020

1 reference

Induction of DNA methylation and gene silencing by short interfering RNAs in human cells

31 March 2020

1 reference

Small interfering RNA-induced transcriptional gene silencing in human cells

31 March 2020

1 reference

Establishment and maintenance of a heterochromatin domain

31 March 2020

1 reference

Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi

31 March 2020

1 reference

Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing

31 March 2020

1 reference

RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing

31 March 2020

1 reference

RNase III enzymes and the initiation of gene silencing

31 March 2020

1 reference

Mechanisms of gene silencing by double-stranded RNA

31 March 2020

1 reference

ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM1568

1 reference

11 August 2017

1 reference