(Q35981432)

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An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

An apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

I Dafnis

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

A K Tzinia

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

E C Tsilibary

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

V I Zannis

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

A Chroni

5

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Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

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publication date

14 March 2012

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Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

210

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

21-32

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions

1 reference

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2 October 2017

Assessing the contribution of inflammation in models of Alzheimer's disease

1 reference

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2 October 2017

Intraneuronal Aβ as a trigger for neuron loss: can this be translated into human pathology?

1 reference

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2 October 2017

Domains of apoE4 required for the biogenesis of apoE-containing HDL.

1 reference

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2 October 2017

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain

1 reference

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2 October 2017

Neuroinflammatory processes in Alzheimer's disease

1 reference

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2 October 2017

Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer's disease

1 reference

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2 October 2017

An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42

1 reference

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2 October 2017

Mechanisms underlying inflammation in neurodegeneration

1 reference

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2 October 2017

Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy

1 reference

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2 October 2017

Does neuroinflammation fan the flame in neurodegenerative diseases?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Increased matrix metalloproteinase 9 activity in mild cognitive impairment

1 reference

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2 October 2017

The role of apolipoprotein E in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Biophysical analysis of progressive C-terminal truncations of human apolipoprotein E4: insights into secondary structure and unfolding properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Review on the APP/PS1KI mouse model: intraneuronal Abeta accumulation triggers axonopathy, neuron loss and working memory impairment

1 reference

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2 October 2017

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Intracellular amyloid-beta in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Inflammation in Alzheimer disease: driving force, bystander or beneficial response?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Synaptic scaling mediated by glial TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

A 13 kDa carboxy-terminal fragment of ApoE stabilizes Abeta hexamers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Tissue inhibitor of metalloproteinase (TIMP)-1: the TIMPed balance of matrix metalloproteinases in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.

1 reference

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2 October 2017

Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

TIMPs and MMPs expression in CSF from patients with TSP/HAM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

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2 October 2017

Interleukin-10 in the brain.

1 reference

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2 October 2017

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

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2 October 2017

A new mathematical model for relative quantification in real-time RT-PCR

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2 October 2017

Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

2 October 2017

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

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2 October 2017

Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein

1 reference

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2 October 2017

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

1 reference

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2 October 2017

Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

11 July 2018

Cell and agonist-specific regulation of genes for matrix metalloproteinases and their tissue inhibitors by primary glial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

11 July 2018

Cytokines regulate gelatinase A and B (matrix metalloproteinase 2 and 9) activity in cultured rat astrocytes

1 reference

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11 July 2018

Localization of tissue inhibitor of matrix metalloproteinases in Alzheimer's disease and normal brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

11 July 2018

Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

11 July 2018

Cerebrospinal fluid apolipoprotein E concentration decreases after seizure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Matrix metalloprotease-9 inhibition improves amyloid beta-mediated cognitive impairment and neurotoxicity in mice

1 reference

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24 September 2018

Neuronal TIMP-1 release accompanies astrocytic MMP-9 secretion and enhances astrocyte proliferation induced by beta-amyloid 25-35 fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Isoform-specific effects of apolipoprotein E on secretion of inflammatory mediators in adult rat microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response

1 reference

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24 September 2018

Cerebrospinal fluid apolipoprotein E concentration decreases after traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Tissue inhibitors of matrix metalloproteinases are elevated in cerebrospinal fluid of neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Expression of matrix metalloproteinase-9 and urinary-type plasminogen activator in Alzheimer's disease brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Reprogramming of TIMP-1 and TIMP-3 expression profiles in brain microvascular endothelial cells and astrocytes in response to proinflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Microglial activation in Alzheimer disease: Association with APOE genotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358542

24 September 2018

Apolipoprotein E polymorphism and serum concentration in Alzheimer's disease in nine European centres: the ApoEurope study. ApoEurope group

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of matrix glycation on expression of type IV collagen, MMP-2, MMP-9 and TIMP-1 by human mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dominant IL-10 and TGF-beta mRNA expression in gammadeltaT cells of human early pregnancy decidua suggests immunoregulatory potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the gene expression profile activated by the CC chemokine ligand 5/RANTES and by lipopolysaccharide in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with Alzheimer's disease display a pro-inflammatory phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22445724

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NEUROSCIENCE.2012.03.013

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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