(Q35975429)

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Microglial Amyloid-β1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer's Disease

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Europe PubMed Central

PMC publication ID

11 August 2017

Microglial Amyloid-β1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer's Disease (English)

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Europe PubMed Central

PMC publication ID

11 August 2017

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Alzheimer's disease

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Shun Shimohama

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Europe PubMed Central

PMC publication ID

11 August 2017

Kazuyuki Takata

1

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Kazuyuki Takata

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Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Tetsuya Takada

2

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Europe PubMed Central

PMC publication ID

11 August 2017

Aina Ito

3

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Europe PubMed Central

PMC publication ID

11 August 2017

Mayo Asai

4

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Europe PubMed Central

PMC publication ID

11 August 2017

Manami Tawa

5

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Europe PubMed Central

PMC publication ID

11 August 2017

Yuki Saito

6

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Europe PubMed Central

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11 August 2017

Eishi Ashihara

7

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Europe PubMed Central

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11 August 2017

Hidekazu Tomimoto

8

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11 August 2017

Yoshihisa Kitamura

9

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11 August 2017

publication date

8 May 2012

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Europe PubMed Central

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11 August 2017

International journal of Alzheimer's disease

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Europe PubMed Central

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11 August 2017

2012

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Europe PubMed Central

PMC publication ID

11 August 2017

685739

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Europe PubMed Central

PMC publication ID

11 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2012

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April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

1 reference

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Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors

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Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.

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2 October 2017

Involvement of WAVE accumulation in Abeta/APP pathology-dependent tangle modification in Alzheimer's disease

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2 October 2017

Role of toll-like receptor signalling in Abeta uptake and clearance

1 reference

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2 October 2017

Metabolism of amyloid-beta peptide and Alzheimer's disease

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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

1 reference

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2 October 2017

RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

1 reference

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2 October 2017

Involvement of Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE) and Rac1 in the phagocytosis of amyloid-beta(1-42) in rat microglia

1 reference

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1 reference

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2 October 2017

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

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Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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2 October 2017

Amphoterin includes a sequence motif which is homologous to the Alzheimer's beta-amyloid peptide (Abeta), forms amyloid fibrils in vitro, and binds avidly to Abeta.

1 reference

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New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal

1 reference

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2 October 2017

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

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2 October 2017

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357001

2 October 2017

Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum

1 reference

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2 October 2017

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

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2 October 2017

A molecular model of Alzheimer amyloid beta-peptide fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357001

2 October 2017

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357001

2 October 2017

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357001

2 October 2017

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

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IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.

1 reference

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24 September 2018

Deglycosylated anti-amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration.

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

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Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins

2 references

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24 September 2018

https://api.crossref.org/works/10.1155%2F2012%2F685739

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1 reference

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1 reference

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

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Occurrence of the diffuse amyloid beta-protein (Abeta) deposits with numerous Abeta-containing glial cells in the cerebral cortex of patients with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3357001

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor

1 reference

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Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease

1 reference

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24 September 2018

Identifiers

10.1155/2012/685739

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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