(Q35968476)

11 August 2017

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title

The immunogenetics of asthma and eczema: a new focus on the epithelium (English)

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11 August 2017

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William Cookson

1

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11 August 2017

publication date

1 December 2004

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Nature Reviews Immunology

11 August 2017

published in

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11 August 2017

volume

4

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11 August 2017

issue

12

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11 August 2017

page(s)

978-988

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A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force

11 August 2017

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Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome

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Gene polymorphism in Netherton and common atopic disease

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Association of SPINK5 gene polymorphisms with atopic dermatitis in the Japanese population

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Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides

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Proteolytic activity of Staphylococcus aureus strains isolated from the colonized skin of patients with acute-phase atopic dermatitis.

21 January 2018

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21 January 2018

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Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array

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21 January 2018

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Expression of the SPRR cornification genes is differentially affected by carcinogenic transformation

21 January 2018

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Assignment of psoriasin to human chromosomal band 1q21: coordinate overexpression of clustered genes in psoriasis

21 January 2018

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Positional cloning of a novel gene influencing asthma from chromosome 2q14.

21 January 2018

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Characterization of a common susceptibility locus for asthma-related traits

21 January 2018

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Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma

21 January 2018

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Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

21 January 2018

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Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

21 January 2018

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Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations

21 January 2018

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Competing Functions Encoded in the Allergy-Associated FcϵRIβ Gene

21 January 2018

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Role of prostanoid DP receptor variants in susceptibility to asthma

21 January 2018

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A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E.

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An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population

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TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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Genetic variation in DLG5 is associated with inflammatory bowel disease

21 January 2018

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Functional variants of OCTN cation transporter genes are associated with Crohn disease

21 January 2018

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Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

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CLCA1 gene polymorphisms in chronic obstructive pulmonary disease

21 January 2018

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Epidermal signal transduction and transcription factor activation in activated keratinocytes.

21 January 2018

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Keratins and the keratinocyte activation cycle

21 January 2018

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Human keratinocytes express functional CD14 and toll-like receptor 4.

21 January 2018

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Toll-like receptors in normal and cystic fibrosis airway epithelial cells

21 January 2018

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Interaction of pseudomonas aeruginosa with epithelial cells: identification of differentially regulated genes by expression microarray analysis of human cDNAs

21 January 2018

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The transcriptional responses of respiratory epithelial cells to Bordetella pertussis reveal host defensive and pathogen counter-defensive strategies

21 January 2018

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A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein

21 January 2018

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The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface

21 January 2018

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Natural adjuvants: endogenous activators of dendritic cells

21 January 2018

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The danger model: a renewed sense of self

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Recognition of microbial infection by Toll-like receptors

21 January 2018

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NODs: intracellular proteins involved in inflammation and apoptosis

21 January 2018

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Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

21 January 2018

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Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses.

21 January 2018

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The 18-kDa form of cat allergen Felis domesticus 1 (Fel d 1) is associated with gelatin- and fibronectin-degrading activity

21 January 2018

1 reference

Major allergen Phl p Vb in timothy grass is a novel pollen RNase

21 January 2018

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The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

21 January 2018

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Mammalian defensins in immunity: more than just microbicidal

21 January 2018

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Antimicrobial actions of calcium binding leucocyte L1 protein, calprotectin

21 January 2018

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In vitro antimicrobial activity of the human neutrophil cytosolic S-100 protein complex, calprotectin, against Capnocytophaga sputigena

21 January 2018

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Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

21 January 2018

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Sensing pathogens and tuning immune responses

21 January 2018

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Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity

21 January 2018

1 reference

Controlling the Toll road to dendritic cell polarization

21 January 2018

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Give us this day our daily germs

21 January 2018

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Effects of intestinal microflora and the environment on the development of asthma and allergy

21 January 2018

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Commensal host-bacterial relationships in the gut

21 January 2018

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Does early exposure to cat or dog protect against later allergy development?

21 January 2018

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Skin test reactivity and number of siblings

21 January 2018

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Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey

21 January 2018

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Farm residence and exposures and the risk of allergic diseases in New Zealand children

21 January 2018

1 reference

Novel specific chemtactic receptor for S100L protein on guinea pig eosinophils

21 January 2018

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S100 protein CP-10 stimulates myeloid cell chemotaxis without activation

21 January 2018

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Transendothelial migration of 27E10+ human monocytes

21 January 2018

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RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

21 January 2018

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Searching for Psoriasis Susceptibility Genes in Italy: Genome Scan and Evidence for a New Locus on Chromosome 1

21 January 2018

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Searching for the cause of the increase in asthma.

21 January 2018

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31 March 2020

Air pollution and asthma

1 reference

Hay fever, hygiene, and household size

31 March 2020

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The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both?

31 March 2020

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A controlled trial of immunotherapy for asthma in allergic children

31 March 2020

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Is immunotherapy for asthma worthwhile?

31 March 2020

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Atopic dermatitis: a genetic-epidemiologic study in a population-based twin sample

31 March 2020

1 reference

A new gene for asthma: would you ADAM and Eve it?

31 March 2020

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A region of chromosome 20 is linked to leprosy susceptibility in a South Indian population

31 March 2020

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A clinical and immunological study of Netherton's syndrome

31 March 2020

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Staphylococcus aureus in the lesions of atopic dermatitis

31 March 2020

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Contrasting disease patterns in psoriasis and atopic dermatitis

31 March 2020

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Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

31 March 2020

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Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21

31 March 2020

1 reference

Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis

31 March 2020

1 reference

Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies

31 March 2020

1 reference

LD mapping of maternally and non-maternally derived alleles and atopy in FcεRI-β

31 March 2020

1 reference

Tumour necrosis factor haplotypes and asthma

31 March 2020

1 reference

31 March 2020

Psoriasis and HLA-Cw6

1 reference

Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis

31 March 2020

1 reference

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

31 March 2020

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Association of the hCLCA1 gene with childhood and adult asthma

31 March 2020

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Elafin (elastase-specific inhibitor) has anti-microbial activity against gram-positive and gram-negative respiratory pathogens

31 March 2020

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Synergistic and additive killing by antimicrobial factors found in human airway surface liquid

31 March 2020

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Secretory leukoprotease inhibitor: a native antimicrobial protein presenting a new therapeutic option?

31 March 2020

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Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung

31 March 2020

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Antimicrobial peptides as mediators of epithelial host defense

31 March 2020

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Soluble proteins of bronchopulmonary secretions from patients with cystic fibrosis, asthma, and bronchitis

31 March 2020

1 reference

DNA microarrays to study gene expression in allergic airways

31 March 2020

1 reference

Immunoglobulin deficiencies in an atopic population

31 March 2020

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Correlation between serum immunoglobulin A concentrations and allergic manifestations in infants

31 March 2020

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Pulmonary innate immune proteins and receptors that interact with gram-positive bacterial ligands

31 March 2020

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The leucocyte protein L1 (calprotectin): a putative nonspecific defence factor at epithelial surfaces.

31 March 2020

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Intestinal microflora of Estonian and Swedish infants

31 March 2020

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The intestinal microflora in allergic Estonian and Swedish 2-year-old children

31 March 2020

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Childhood environment and adult atopy: results from the European Community Respiratory Health Survey

31 March 2020

1 reference

Psoriasin: a novel chemotactic protein

31 March 2020

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S100A8: emerging functions and regulation.

31 March 2020

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Purification and characterization of the cytotoxic factor in rat peritoneal exudate cells: its identification as the calcium binding protein complex, calprotectin

31 March 2020

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Epithelioid cells from foreign-body granuloma selectively express the calcium-binding protein MRP-14, a novel down-regulatory molecule of macrophage activation

31 March 2020

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Effects of human calprotectin (L1) on in vitro immunoglobulin synthesis

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1500

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11 August 2017

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