(Q35845976)

English

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

scientific article published in September 1995

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Joseph Sodroski

6

object named as

J Sodroski

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Richard T. Wyatt

1

object named as

R Wyatt

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

J Moore

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

M Accola

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

E Desjardin

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

J Robinson

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 September 1995

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

Journal of Virology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

69

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

5723-5733

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189432

27 July 2018

Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189432

27 July 2018

Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189432

27 July 2018

Adaptation of two primary human immunodeficiency virus type 1 isolates to growth in transformed T cell lines correlates with alterations in the responses of their envelope glycoproteins to soluble CD4.

1 reference

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Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions

1 reference

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27 July 2018

Evidence for the cooperation of gp120 amino acids 322 and 448 in SIVmac entry

1 reference

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27 July 2018

gp120-independent fusion mediated by the human immunodeficiency virus type 1 gp41 envelope glycoprotein: a reassessment

1 reference

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Determinants of human immunodeficiency virus type 1 entry in the CDR2 loop of the CD4 glycoprotein.

1 reference

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Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.

1 reference

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27 July 2018

Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid)

1 reference

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27 July 2018

Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding

1 reference

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27 July 2018

Probing the structure of the V2 domain of human immunodeficiency virus type 1 surface glycoprotein gp120 with a panel of eight monoclonal antibodies: human immune response to the V1 and V2 domains

1 reference

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Characterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120

1 reference

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Immunochemical analysis of the gp120 surface glycoprotein of human immunodeficiency virus type 1: probing the structure of the C4 and V4 domains and the interaction of the C4 domain with the V3 loop

1 reference

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

1 reference

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Identification and characterization of monoclonal antibodies specific for polymorphic antigenic determinants within the V2 region of the human immunodeficiency virus type 1 envelope glycoprotein.

1 reference

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27 July 2018

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies

1 reference

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

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The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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27 July 2018

Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1

1 reference

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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A soluble form of CD4 (T4) protein inhibits AIDS virus infection

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pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

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The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

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Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients

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27 July 2018

Soluble CD4 molecules neutralize human immunodeficiency virus type 1.

1 reference

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27 July 2018

HIV infection is blocked in vitro by recombinant soluble CD4.

1 reference

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27 July 2018

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein

1 reference

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Designing CD4 immunoadhesins for AIDS therapy

1 reference

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27 July 2018

Generation and characterization of monoclonal antibodies to the putative CD4-binding domain of human immunodeficiency virus type 1 gp120.

1 reference

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27 July 2018

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

1 reference

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27 July 2018

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1 reference

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HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelope

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Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS.

1 reference

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High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates

1 reference

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Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation

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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

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Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants

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Enhancement of SIV infection with soluble receptor molecules

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27 July 2018

Dissociation of gp120 from HIV-1 virions induced by soluble CD4.

1 reference

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27 July 2018

Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189432

27 July 2018

Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding

1 reference

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Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41

1 reference

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27 July 2018

Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/CD4 binding in human immunodeficiency virus 1-infected humans

1 reference

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Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes

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Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.

1 reference

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Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene

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27 July 2018

Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain

1 reference

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Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophages

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Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

1 reference

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Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity

1 reference

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Alteration of HIV-1 infectivity and neutralization by a single amino acid replacement in the V3 loop domain

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Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity

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The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism

1 reference

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Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates

1 reference

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A human monoclonal antibody against the CD4-binding site of HIV1 gp120 exhibits potent, broadly neutralizing activity

1 reference

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Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120

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27 July 2018

Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibody

1 reference

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Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody

1 reference

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Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding

1 reference

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An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection

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Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody

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Mutations in the leucine zipper of the human immunodeficiency virus type 1 transmembrane glycoprotein affect fusion and infectivity

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The transmembrane glycoprotein of human immunodeficiency virus type 1 induces syncytium formation in the absence of the receptor binding glycoprotein

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Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo

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Human immunodeficiency virus type 1 envelope glycoprotein molecules containing membrane fusion-impairing mutations in the V3 region efficiently undergo soluble CD4-stimulated gp120 release

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Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: definition of critical amino acids involved in cell tropism

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Inhibition of viral replication by monoclonal antibodies directed against human immunodeficiency virus gp120

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Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein

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Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120

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Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region

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Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 molecule

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Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.

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A molecular clone of HTLV-III with biological activity.

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Relation of phenotype evolution of HIV-1 to envelope V2 configuration

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a new neutralizing epitope conformationally affected by the attachment of CD4 to gp120

1 reference

https://pubmed.ncbi.nlm.nih.gov/7543586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble CD4 and dextran sulfate mediate release of gp120 from HIV-1: implications for clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/7543586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/7543586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7543586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single amino-acid changes in HIV envelope affect viral tropism and receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/7543586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.69.9.5723-5733.1995

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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