(Q35691719)

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Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA. (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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primates

1 reference

based on heuristic

inferred from title

8

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Mark E Davis

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

6

object named as

Ryan K Zeidan

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Joanna Yi-Ching Liu

3

object named as

Joanna Yi-Ching Liu

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Jeremy D Heidel

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Zhongping Yu

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Shyam M Rele

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Yongchao Liang

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Douglas J Kornbrust

7

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Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

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publication date

22 March 2007

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Europe PubMed Central

PubMed publication ID

9 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

9 August 2017

104

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

5715-5721

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Combination of active and inactive siRNA targeting the mitotic kinesin Eg5 impairs silencing efficiency in several cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Imidazole groups on a linear, cyclodextrin-containing polycation produce enhanced gene delivery via multiple processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Ligand-targeted delivery of therapeutic siRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Aptamer mediated siRNA delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Technology evaluation: TransMID, KS Biomedix/Nycomed/Sosei/PharmaEngine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Development of an ultrasensitive noncompetitive hybridization-ligation enzyme-linked immunosorbent assay for the determination of phosphorothioate oligodeoxynucleotide in plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Drug-induced phospholipidosis: are there functional consequences?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Antineoplastic drugs that interfere with iron metabolism in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Transferrin receptors in human tissues: their distribution and possible clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

27 July 2018

Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

RNAi therapeutics: a potential new class of pharmaceutical drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

RNAi-mediated gene silencing in non-human primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Single cell kinetics of intracellular, nonviral, nucleic acid delivery vehicle acidification and trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Repeated injections of PEG-PE liposomes generate anti-PEG antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Cationic liposome-mediated delivery of siRNAs in adult mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Role of complement activation in hypersensitivity reactions to doxil and hynic PEG liposomes: experimental and clinical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Pharmacokinetics, toxicity, and efficacy of ends-modified raf antisense oligodeoxyribonucleotide encapsulated in a novel cationic liposome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: potential mechanism of action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829492

25 September 2018

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liposome-induced pulmonary hypertension: properties and mechanism of a complement-mediated pseudoallergic reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary clinical study of transferrin-adriamycin conjugate for drug delivery to acute leukemia patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of interferon response in animals to naked siRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17379663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0701458104

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2007PNAS..104.5715H

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

0 references

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