(Q35462835)

English

Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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1 reference

based on heuristic

inferred from title

multisystem proteinopathy

1 reference

based on heuristic

inferred from title

Virginia Kimonis

5

object named as

Virginia E Kimonis

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Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Angèle Nalbandian

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Katrina J Llewellyn

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Christopher Nguyen

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Puya G Yazdi

4

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Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

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publication date

17 April 2015

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Europe PubMed Central

PubMed publication ID

8 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

10

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Europe PubMed Central

PubMed publication ID

8 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

e0122888

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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Creative Commons Attribution 4.0 International

17 April 2015

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April 2022 Public Data File from Crossref

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0 references

Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature

1 reference

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1 reference

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Rapamycin: one drug, many effects

1 reference

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Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function

1 reference

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Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux

1 reference

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mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome

1 reference

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Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease

1 reference

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27 July 2018

Rapamycin-induced autophagy aggravates pathology and weakness in a mouse model of VCP-associated myopathy

1 reference

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27 July 2018

A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse

1 reference

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27 July 2018

Autophagy as a new therapeutic target in Duchenne muscular dystrophy

1 reference

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The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice

1 reference

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Autophagy: a double-edged sword in Alzheimer's disease

1 reference

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27 July 2018

Autophagy in lysosomal myopathies

1 reference

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27 July 2018

Fighting neurodegeneration with rapamycin: mechanistic insights

1 reference

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27 July 2018

VCP Associated Inclusion Body Myopathy and Paget Disease of Bone Knock-In Mouse Model Exhibits Tissue Pathology Typical of Human Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Valosin containing protein associated inclusion body myopathy: abnormal vacuolization, autophagy and cell fusion in myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

VCP disease associated with myopathy, Paget disease of bone and frontotemporal dementia: review of a unique disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Autophagy in the Pathogenesis of Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Autophagy and neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Central pore residues mediate the p97/VCP activity required for ERAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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Extension of chronological life span in yeast by decreased TOR pathway signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

27 July 2018

Genetics: influence of TOR kinase on lifespan in C. elegans

1 reference

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Cdc48-Ufd1-Npl4: stuck in the middle with Ub.

1 reference

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Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy, Paget disease of bone, and frontotemporal dementia

1 reference

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

1 reference

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Diagnostic imaging for a case of maxillary myxoma with a review of the magnetic resonance images of myxoid lesions

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Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression

1 reference

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Metastatic perivascular epithelioid cell tumor responding to mammalian target of rapamycin inhibition

1 reference

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Inclusion body myopathy with Paget disease of the bone and frontotemporal dementia associated with a novel G156S mutation in the VCP gene.

1 reference

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1 reference

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1 reference

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1 reference

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Autophagy gone awry in neurodegenerative diseases

1 reference

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Two Australian families with inclusion-body myopathy, Paget's disease of bone and frontotemporal dementia: novel clinical and genetic findings

1 reference

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A novel mutation in the VCP gene (G157R) in a German family with inclusion-body myopathy with Paget disease of bone and frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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Inclusion body myopathy, Paget's disease of the bone and frontotemporal dementia: recurrence of the VCP R155H mutation in an Italian family and implications for genetic counselling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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Clinical studies in familial VCP myopathy associated with Paget disease of bone and frontotemporal dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

26 September 2018

Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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Valosin-containing protein gene mutations: clinical and neuropathologic features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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Autosomal dominant inclusion body myopathy, Paget disease of bone, and frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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1 reference

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Mutant valosin-containing protein causes a novel type of frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4401571

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Inclusion body myopathy and Paget disease is linked to a novel mutation in the VCP gene

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122888

21 January 2018

Inclusion body myopathy with Paget disease and frontotemporal dementia (IBMPFD): clinical features including sphincter disturbance in a large pedigree

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inclusion body myopathy and frontotemporal dementia caused by a novel VCP mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful treatment of subungual fibromas of tuberous sclerosis with topical rapamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and molecular studies in a unique family with autosomal dominant limb-girdle muscular dystrophy and Paget disease of bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/25884947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0122888

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

2015PLoSO..1022888N

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

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