(Q35145640)

6 August 2017

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title

The CD40-CD154 interaction in B cell-T cell liaisons (English)

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6 August 2017

Gail A Bishop

1

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6 August 2017

Bruce S Hostager

series ordinal

2

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6 August 2017

publication date

1 June 2003

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Cytokine and Growth Factor Reviews

6 August 2017

published in

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6 August 2017

volume

14

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6 August 2017

issue

3-4

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6 August 2017

page(s)

297-309

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A p50 surface antigen restricted to human urinary bladder carcinomas and B lymphocytes.

6 August 2017

cites work

1 reference

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7 January 2021

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

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7 January 2021

Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM

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7 January 2021

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

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7 January 2021

CD40 ligand and its role in X-linked hyper-IgM syndrome

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7 January 2021

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes

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https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Molecular and biological characterization of a murine ligand for CD40

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https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

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https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Mice deficient for the CD40 ligand

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7 January 2021

CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 ligand-transduced co-stimulation of T cells in the development of helper function

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https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 ligand is required for protective cell-mediated immunity to Leishmania major

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https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

A central role of CD40 ligand in the regulation of CD4+ T-cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40-CD40 ligand interactions in vivo regulate migration of antigen-bearing dendritic cells from the skin to draining lymph nodes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Polyclonal activation of immature B cells by preactivated T cells: the role of IL-4 and CD40 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Engagement of CD40 lowers the threshold for activation of resting B cells via antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Co-stimulation by anti-immunoglobulin is required for B cell activation by CD40Llow T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Signaling via major histocompatibility complex class II molecules and antigen receptors enhances the B cell response to gp39/CD40 ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 ligand triggers interleukin-6 mediated B cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The immune response modifier resiquimod mimics CD40-induced B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 ligation induces lymphotoxin alpha gene expression in human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activation of tumor necrosis factor-alpha and lymphotoxin-alpha via anti-CD40 in human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40‐mediated lymphotoxin α expression in human B cells is tyrosine kinase dependent

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Lymphotoxin-alpha is an important autocrine factor for CD40 + interleukin-4-mediated B-cell activation in normal and atopic donors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The role of B cells in the programming of T cells for IL-4 synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Role of B cells as antigen-presenting cells in vivo revisited: antigen-specific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Ku in the cytoplasm associates with CD40 in human B cells and translocates into the nucleus following incubation with IL-4 and anti-CD40 mAb

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Isotype Switching by Human B Cells Is Division-Associated and Regulated by Cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The CD40 antigen and its ligand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Assembly and Regulation of the CD40 Receptor Complex in Human B Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Regulation of TRAF2 signaling by self-induced degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

ICOS is critical for CD40-mediated antibody class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Lineage-restricted function of nuclear factor kappaB-inducing kinase (NIK) in transducing signals via CD40.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Molecular mechanisms of B lymphocyte activation by the immune response modifier R-848.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kappa B, AP-1, and C/EBP.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The B cell-specific transcription factor BSAP regulates B cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Induction of the transcription factors NF-kappa B, AP-1 and NF-AT during B cell stimulation through the CD40 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Modulation of E2F activity in primary mouse B cells following stimulation via surface IgM and CD40 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Evidence for a CD40 response element, distinct from the IL-4 response element, in the germline epsilon promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

B lymphocyte activation by contact-mediated interactions with T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Rescue from anti‐IgM‐induced programmed cell death by the B cell surface proteins CD20 and CD40

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Antibodies to murine CD40 protect normal and malignant B cells from induced growth arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Distinct mechanisms for rescue from apoptosis in Ramos human B cells by signaling through CD40 and interleukin-4 receptor: role for inhibition of an early response gene, Berg36

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD27: a memory B-cell marker

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The T cell-B cell interaction via OX40-OX40L is necessary for the T cell-dependent humoral immune response

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD134L engagement enhances human B cell Ig production: CD154/CD40, CD70/CD27, and CD134/CD134L interactions coordinately regulate T cell-dependent B cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD95's deadly mission in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Germinal center B cells rescued from apoptosis by CD40 ligation or attachment to follicular dendritic cells, but not by engagement of surface immunoglobulin or adhesion receptors, become resistant to CD95-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Regulation of the Fas death pathway by FLICE-inhibitory protein in primary human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

Mechanism and control of class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

The immunoglobulin class switch: beyond "accessibility".

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

CD40 and its ligand in host defense

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2803%2900024-8

7 January 2021

10.1016/S1359-6101(03)00024-8

Identifiers

DOI

1 reference

6 August 2017

1 reference