(Q35110573)

English

Gene Therapy for Pancreatic Cancer Targeting the Genomic Alterations of Tumor Suppressor Genes using Replication-selective Oncolytic Adenovirus

scientific article published on September 1, 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

Gene therapy for pancreatic cancer targeting the genomic alterations of tumor suppressor genes using replication-selective oncolytic adenovirus (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Gene Therapy for Pancreatic Cancer Targeting the Genomic Alterations of Tumor Suppressor Genes using Replication-selective Oncolytic Adenovirus (English)

1 reference

10.1111/J.1749-0774.2002.TB00108.X

https://api.crossref.org/works/10.1111/J.1749-0774.2002.TB00108.X

25 December 2023

0 references

oncolytic virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pancreatic cancer

1 reference

based on heuristic

inferred from title

viral replication

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12703544

25 December 2023

tumor suppressor gene

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12703544

25 December 2023

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12703544

25 December 2023

1 reference

10.1111/J.1749-0774.2002.TB00108.X

https://api.crossref.org/works/10.1111/J.1749-0774.2002.TB00108.X

25 December 2023

3

object named as

Fuyuhiko Motoi

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12703544

25 December 2023

8

object named as

Akira Horii

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12703544

25 December 2023

author name string

Makoto Sunamura

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Masaru Oonuma

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Hisashi Abe

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Yukoh Saitoh

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Toru Hoshida

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Shigeru Ottomo

7

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Seiki Matsuno

9

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 September 2002

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

138-150

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Karyotypic abnormalities in tumours of the pancreas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-0774.2002.TB00108.X

21 January 2018

Association of p53 gene mutations with short survival in pancreatic adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-0774.2002.TB00108.X

21 January 2018

Transcriptional control by E2F

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A deadly inheritance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method of limited replication for the efficient in vivo delivery of adenovirus to cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The retinoblastoma protein and cell cycle control

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy for intraperitoneally disseminated pancreatic cancers by Escherichia coli uracil phosphoribosiltransferase (UPRT) gene mediated by restricted replication-competent adenoviral vectors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allelotype of pancreatic adenocarcinoma using xenograft enrichment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of three commonly deleted regions on chromosome arm 6q in human pancreatic cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of loss of alleles on the short arms of chromosomes 11 and 17 with metastasis of primary breast cancer to lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effective gene therapy for pancreatic cancer by cytokines mediated by restricted replication-competent adenovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Karyotypic pattern of pancreatic adenocarcinomas correlates with survival and tumour grade

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of interleukin-2, interleukin-12, and dendritic cells in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer-susceptibility genes. Gatekeepers and caretakers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic indicators for survival after resection of pancreatic adenocarcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: identification of a I-cM region of common allelic loss.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the use of viruses in the treatment of carcinoma of the cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiangiogenesis effect of interleukin 12 during early growth of human pancreatic cancer in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans complementation of an E1A-deleted adenovirus with codelivered E1A sequences to make recombinant adenoviral producer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of human colorectal carcinoma cell growth by wild-type p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ONYX-015: clinical data are encouraging

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of P53 gene mutations in a large series of node-negative breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E1A RNA transcripts amplify adenovirus-mediated tumor reduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53, Ki-ras, and DNA ploidy in human pancreatic ductal adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12703544

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1749-0774.2002.TB00108.X

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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