(Q35028704)

5 August 2017

1 reference

title

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization (English)

1 reference

G protein-coupled receptor

5 August 2017

main subject

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2

Robert J Lefkowitz

1 reference

5 August 2017

Trudy A Kohout

1

1 reference

5 August 2017

publication date

1 January 2003

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5 August 2017

published in

Molecular Pharmacology

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5 August 2017

volume

63

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5 August 2017

issue

1

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5 August 2017

page(s)

9-18

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Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart

5 August 2017

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Regulation of G protein-coupled receptor kinase subtypes by calcium sensor proteins.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Vasoactive intestinal polypeptide type-1 receptor regulation. Desensitization, phosphorylation, and sequestration.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Beta-adrenergic receptor kinase: primary structure delineates a multigene family

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Inhibition of rhodopsin kinase by recoverin. Further evidence for a negative feedback system in phototransduction

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Degradation of the G protein-coupled receptor kinase 2 by the proteasome pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

beta -Arrestins regulate protease-activated receptor-1 desensitization but not internalization or Down-regulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Characterization of the G Protein-coupled Receptor Kinase GRK4

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

G protein-coupled receptor kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Localization of the sites for Ca2+-binding proteins on G protein-coupled receptor kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Mammalian RGS Proteins: Barbarians at the Gate

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

PDE4 cAMP-specific phosphodiesterases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Heterotrimeric G proteins: organizers of transmembrane signals

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

c-Src tyrosine kinase binds the beta 2-adrenergic receptor via phospho-Tyr-350, phosphorylates G-protein-linked receptor kinase 2, and mediates agonist-induced receptor desensitization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Regulation of rhodopsin phosphorylation by a family of neuronal calcium sensors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Prolonged photoresponses in transgenic mouse rods lacking arrestin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Agonist-dependent phosphorylation of the G protein-coupled receptor kinase 2 (GRK2) by Src tyrosine kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Regulation of G Protein-coupled Receptor Kinases by Calmodulin and Localization of the Calmodulin Binding Domain

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Inhibition of G protein-coupled receptor kinase subtypes by Ca2+/calmodulin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Ca(2+)-dependent interaction of recoverin with rhodopsin kinase.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaq

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

A role for receptor kinases in the regulation of class II G protein-coupled receptors. Phosphorylation and desensitization of the secretin receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

G protein-coupled receptor kinase 4 gene variants in human essential hypertension

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

G Protein-coupled Receptor Kinase 3 (GRK3) Gene Disruption Leads to Loss of Odorant Receptor Desensitization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Phosphorylation-independent regulation of metabotropic glutamate receptor signaling by G protein-coupled receptor kinase 2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Mice lacking G-protein receptor kinase 1 have profoundly slowed recovery of cone-driven retinal responses

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Phosphorylation and Activation of β-Adrenergic Receptor Kinase by Protein Kinase C

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Arresting developments in heptahelical receptor signaling and regulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Domains of the parathyroid hormone (PTH) receptor required for regulation by G protein-coupled receptor kinases (GRKs).

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Clathrin-mediated Endocytosis of the β-Adrenergic Receptor Is Regulated by Phosphorylation/Dephosphorylation of β-Arrestin1

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Enhanced morphine analgesia in mice lacking beta-arrestin 2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein)

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

β-Arrestin1 Knockout Mice Appear Normal but Demonstrate Altered Cardiac Responses to β-Adrenergic Stimulation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Agonist-dependent modulation of G protein-coupled receptor kinase 2 by mitogen-activated protein kinases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

A novel subtype of G-protein-coupled receptor kinase, GRK7, in teleost cone photoreceptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.63.1.9

Identifiers

DOI

10.1124/MOL.63.1.9

1 reference

5 August 2017

1 reference