(Q35006483)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

review article

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title

Alzheimer's and prion diseases: distinct pathologies, common proteolytic denominators (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

0 references

0 references

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

author name string

Bruno Vincent

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

publication date

1 December 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

published in

Trends in Neurosciences

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

volume

25

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

issue

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

page(s)

616-620

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

Prion protein amyloidosis

15 December 2019

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

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The shifting biology of prions

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Prion diseases: what is the neurotoxic molecule?

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Prion and prejudice: normal protein and the synapse

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Alzheimer's disease and the amyloid beta protein: What is the role of amyloid?

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Neurotoxicity of a prion protein fragment

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Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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7 January 2021

Prion protein peptides: optimal toxicity and peptide blockade of toxicity

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7 January 2021

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

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7 January 2021

In vivo cytotoxicity of the prion protein fragment 106-126

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7 January 2021

Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations

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7 January 2021

Activation of caspase-3 in beta-amyloid-induced apoptosis of cultured rat cortical neurons

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7 January 2021

Caspase-3 activation by beta-amyloid and prion protein peptides is independent from their neurotoxic effect

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7 January 2021

Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis

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7 January 2021

Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons.

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7 January 2021

Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

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7 January 2021

PrP and β‐Amyloid Fragments Activate Different Neurotoxic Mechanisms in Cultured Mouse Cells

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7 January 2021

Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

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7 January 2021

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7 January 2021

Regulation of the alpha-secretase ADAM10 by its prodomain and proprotein convertases.

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7 January 2021

Coordinated Expression of β-Amyloid Precursor Protein and the Putative β-Secretase BACE and α-Secretase ADAM10 in Mouse and Human Brain

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7 January 2021

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

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7 January 2021

Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites.

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7 January 2021

Truncated forms of the human prion protein in normal brain and in prion diseases

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7 January 2021

Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues

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7 January 2021

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7 January 2021

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7 January 2021

Beta-amyloid precursor protein cleavage by a membrane-bound protease

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7 January 2021

The beta-secretase, BACE: a prime drug target for Alzheimer's disease

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7 January 2021

Mice devoid of PrP are resistant to scrapie

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7 January 2021

Normal host prion protein necessary for scrapie-induced neurotoxicity

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7 January 2021

Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion

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7 January 2021

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

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7 January 2021

Alzheimer disease and the prion disorders amyloid beta-protein and prion protein amyloidoses

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7 January 2021

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

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7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

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7 January 2021

10.1016/S0166-2236(02)02263-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12446128%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference