(Q34988243)

5 August 2017

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title

Hepatitis C virus replicons: potential role for drug development (English)

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5 August 2017

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Ralf Bartenschlager

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publication date

1 November 2002

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Nature Reviews Drug Discovery

5 August 2017

published in

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5 August 2017

volume

1

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5 August 2017

issue

11

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5 August 2017

page(s)

911-916

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Hepatitis C virus infection

5 August 2017

cites work

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Replication of hepatitis C virus

31 March 2020

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Recent advances in the molecular biology of hepatitis C virus

31 March 2020

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Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function

31 March 2020

1 reference

A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs

31 March 2020

1 reference

Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

31 March 2020

1 reference

Evidence for a new hepatitis C virus antigen encoded in an overlapping reading frame

31 March 2020

1 reference

C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity

31 March 2020

1 reference

Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein

31 March 2020

1 reference

Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

31 March 2020

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Novel cell culture systems for the hepatitis C virus

31 March 2020

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

31 March 2020

1 reference

Efficient initiation of HCV RNA replication in cell culture

31 March 2020

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

31 March 2020

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Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

31 March 2020

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Effect of alpha interferon on the hepatitis C virus replicon

31 March 2020

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Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells

31 March 2020

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Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

31 March 2020

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Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

31 March 2020

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Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.

31 March 2020

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Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication

31 March 2020

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Mutations in NS5B polymerase of hepatitis C virus: impacts on in vitro enzymatic activity and viral RNA replication in the subgenomic replicon cell culture

31 March 2020

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Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs

31 March 2020

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Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

31 March 2020

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Regulation of PKR and IRF-1 during hepatitis C virus RNA replication

31 March 2020

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Characterization of cell lines carrying self-replicating hepatitis C virus RNAs

31 March 2020

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New antiviral agents for the therapy of chronic hepatitis B virus infection

31 March 2020

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Replication of subgenomic hepatitis A virus RNAs expressing firefly luciferase is enhanced by mutations associated with adaptation of virus to growth in cultured cells

31 March 2020

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Cell clones selected from the Huh7 human hepatoma cell line support efficient replication of a subgenomic GB virus B replicon

31 March 2020

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Subgenomic replicon derived from a cell line infected with the hepatitis C virus

31 March 2020

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Production of hepatitis B virus by a differentiated human hepatoma cell line after transfection with cloned circular HBV DNA.

31 March 2020

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Internal ribosome entry site within hepatitis C virus RNA

31 March 2020

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7 January 2021

Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism

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7 January 2021

The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)

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7 January 2021

Characterization of an Autonomous Subgenomic Pestivirus RNA Replicon

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7 January 2021

Construction and characterization of poliovirus subgenomic replicons

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7 January 2021

Identifiers

DOI

10.1038/NRD942

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5 August 2017

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