(Q34980526)

5 August 2017

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title

The dual role of thymidine phosphorylase in cancer development and chemotherapy (English)

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5 August 2017

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Annelies Bronckaers

1

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Federico Gago

object named as

Federico Gago

series ordinal

2

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Jan Balzarini

series ordinal

3

object named as

Jan Balzarini

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5 August 2017

Sandra Liekens

4

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5 August 2017

publication date

1 November 2009

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Medicinal Research Reviews

5 August 2017

published in

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5 August 2017

volume

29

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5 August 2017

issue

6

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5 August 2017

page(s)

903-953

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Catabolism of thymidine in human blood platelets purification and properties of thymidine phosphorylase

5 August 2017

cites work

1 reference

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): clinical, biochemical, and genetic features of an autosomal recessive mitochondrial disorder

21 January 2018

1 reference

Expression of thymidine phosphorylase in human gastric carcinoma.

21 January 2018

1 reference

Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer

21 January 2018

1 reference

Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer

21 January 2018

1 reference

Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma

21 January 2018

1 reference

The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium

21 January 2018

1 reference

Different patterns of stromal and cancer cell thymidine phosphorylase reactivity in non-small-cell lung cancer: impact on tumour neoangiogenesis and survival

21 January 2018

1 reference

Association of tumour necrosis factor alpha and its receptors with thymidine phosphorylase expression in invasive breast carcinoma

21 January 2018

1 reference

Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human bladder cancer.

21 January 2018

1 reference

Co-expression of thymidine phosphorylase and heme oxygenase-1 in macrophages in human malignant vertical growth melanomas.

21 January 2018

1 reference

Expression of thymidine phosphorylase by macrophages in colorectal cancer tissues

21 January 2018

1 reference

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization

21 January 2018

1 reference

Thymidine phosphorylase activity and prodrug effects in a three-dimensional model of angiogenesis: implications for the treatment of ovarian cancer

21 January 2018

1 reference

Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis

21 January 2018

1 reference

Organization and chromosomal localization of the human platelet-derived endothelial cell growth factor gene

21 January 2018

1 reference

Practical considerations in the use of oral fluoropyrimidines

21 January 2018

1 reference

Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase

21 January 2018

1 reference

Enhancement of drug sensitivity and a bystander effect in PC-9 cells transfected with a platelet-derived endothelial cell growth factor thymidine phosphorylase cDNA.

21 January 2018

1 reference

Identification of Mycoplasma pirum genes involved in the salvage pathways for nucleosides

21 January 2018

1 reference

Improvement of purine and pyrimidine antimetabolite-based anticancer treatment by selective suppression of mycoplasma-encoded catabolic enzymes

21 January 2018

1 reference

Mycoplasmal infections prevent apoptosis and induce malignant transformation of interleukin-3-dependent 32D hematopoietic cells

21 January 2018

1 reference

Interferons upregulate thymidine phosphorylase expression via JAK-STAT-dependent transcriptional activation and mRNA stabilization in human glioblastoma cells

21 January 2018

1 reference

12 December 2020

The prognostic significance of microvessel density and thymidine phosphorylase expression in squamous cell carcinoma of the esophagus

1 reference

12 December 2020

Correlation between thymidine phosphorylase expression and invasion phenotype in cervical carcinoma cells

1 reference

12 December 2020

Prognostic significance of thymidine phosphorylase in superficial bladder carcinoma

1 reference

12 December 2020

TGF-alpha as well as VEGF, PD-ECGF and bFGF contribute to angiogenesis of esophageal squamous cell carcinoma

1 reference

12 December 2020

High concentrations of immunoreactive gliostatin/platelet-derived endothelial cell growth factor in synovial fluid and serum of rheumatoid arthritis

1 reference

12 December 2020

Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1.

1 reference

12 December 2020

FLUORINATED PYRIMIDINES. XXI. THE TUMOR-INHIBITORY ACTIVITY OF 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE

1 reference

12 December 2020

The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo.

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12 December 2020

Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice

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12 December 2020

Direct Agar Isolation of Mycoplasmas from Human Leukaemic Bone Marrow

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12 December 2020

Role of thymidine phosphorylase in Fas-induced apoptosis.

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12 December 2020

Expression of uridine and thymidine phosphorylase genes in human breast carcinoma

1 reference

12 December 2020

Angiogenesis and platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in endometrial cancer

1 reference

12 December 2020

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

1 reference

12 December 2020

Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts

1 reference

12 December 2020

Correlation between spontaneous apoptosis and the expression of angiogenic factors in advanced gastric adenocarcinoma

1 reference

12 December 2020

Phase I and II studies of 2'-deoxy-5-(trifluoromethyl)-uridine (NSC-75520).

1 reference

12 December 2020

Immunohistochemical study on tumor angiogenic factors in non-small cell lung cancer.

1 reference

12 December 2020

The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes

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12 December 2020

Angiogenic effect of thymidine phosphorylase on macrophages in glioblastoma multiforme

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12 December 2020

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine

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12 December 2020

p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR.

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12 December 2020

Thymidine phosphorylase and dihydropyrimidine dehydrogenase in renal cell carcinoma: relationship between histological parameters and chemosensitivity to 5-fluorouracil

1 reference

12 December 2020

Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies

1 reference

12 December 2020

Thymidine phosphorylase expression in gastric cancer in association with proliferative activity and angiogenesis

1 reference

12 December 2020

Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma

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12 December 2020

Expression of thymidylate synthase and thymidine phosphorylase in recurrence and survival rates of advanced gastric cancer

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12 December 2020

Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor

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12 December 2020

Partial purification of a thymidine phosphorylase from human gastric cancer

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12 December 2020

Thymidine phosphorylase and vascular endothelial growth factor in patients with Stage I lung adenocarcinoma

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12 December 2020

Evaluation of tumor angiogenesis and thymidine phosphorylase tissue expression in patients with endometrial cancer

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12 December 2020

Platelet-derived endothelial cell growth factor is not implicated in progression of cervical cancer

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12 December 2020

Thymidine phosphorylase inhibits the expression of proapoptotic protein BNIP3.

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12 December 2020

Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil

1 reference

12 December 2020

Tissue distribution of human gliostatin/platelet-derived endothelial cell growth factor (PD-ECGF) and its drug-induced expression

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12 December 2020

Isolation of putative progenitor endothelial cells for angiogenesis

1 reference

12 December 2020

Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity

1 reference

12 December 2020

Expression of thymidine phosphorylase in malignant ovarian tumors: correlation with microvessel density and an ultrasound-derived index of angiogenesis

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12 December 2020

Role of thymidine phosphorylase activity in the angiogenic effect of platelet derived endothelial cell growth factor/thymidine phosphorylase.

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12 December 2020

Thymidine phosphorylase expression in oral squamous cell carcinoma

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12 December 2020

Dihydropyrimidine dehydrogenase (DPD) rapidly regenerates after inactivation by eniluracil (GW776C85) in primary and metastatic colorectal cancer

1 reference

12 December 2020

Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase

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12 December 2020

Expression of platelet-derived endothelial cell growth factor in inflammatory bowel disease

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12 December 2020

SYNTHESES OF 5-TRIFLUOROMETHYLURACIL AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE.

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12 December 2020

Crystallization and X-ray diffraction study of recombinant platelet-derived endothelial cell growth factor

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12 December 2020

Neoangiogenesis in patients with gastric carcinoma in relation to the expression of vascular endothelial growth factor and thymidine phosphorylase

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12 December 2020

Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts.

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12 December 2020

Capecitabine as adjuvant treatment for stage III colon cancer

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12 December 2020

Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors

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12 December 2020

Expression of pyrimidine nucleoside phosphorylase mRNA plays an important role in the prognosis of patients with oesophageal cancer

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12 December 2020

Continuous infusion of chemotherapy: focus on 5-fluorouracil and fluorodeoxyuridine

1 reference

12 December 2020

Exogenous mycoplasmal p37 protein alters gene expression, growth and morphology of prostate cancer cells

1 reference

12 December 2020

Thymidine phosphorylase expression in normal, hyperplastic and neoplastic prostates: correlation with tumour associated macrophages, infiltrating lymphocytes, and angiogenesis

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12 December 2020

Thymidine phosphorylase expression in progression of cervical cancer: correlation with microvessel count, proliferating cell nuclear antigen, and apoptosis

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12 December 2020

Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma

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12 December 2020

Long-term effect of gene therapy for chronic ischemic myocardium using platelet-derived endothelial cell growth factor in dogs

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12 December 2020

Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats

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12 December 2020

Interferon gamma-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through gamma-activated sequence-like element in human macrophages.

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12 December 2020

Molecular biology and pathogenicity of mycoplasmas

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12 December 2020

Inhibition of thymidine phosphorylase by 6-aminothymine and derivatives of 6-aminouracil

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12 December 2020

Expression of the angiogenic factor thymidine phosphorylase in human astrocytic tumors.

1 reference

12 December 2020

Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides.

1 reference

12 December 2020

Expression of thymidine phosphorylase and vascular endothelial cell growth factor in human head and neck squamous cell carcinoma and their different characteristics

1 reference

12 December 2020

Adjuvant capecitabine is at least as effective as fluorouracil plus leucovorin for survival in people with resected stage III colon cancer

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12 December 2020

Correlation between Expression of Platelet-derived Endothelial Cell Growth Factor (Thymidine Phosphorylase) and Microvessel Density in Early-stage Human Colon Carcinomas

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12 December 2020

Altered thymidine metabolism due to defects of thymidine phosphorylase

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12 December 2020

Gene therapy for chronic myocardial ischemia using platelet-derived endothelial cell growth factor in dogs

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12 December 2020

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

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12 December 2020

The expression of thymidine phosphorylase is a prognostic predictor for the intravesical recurrence of superficial bladder cancer

1 reference

12 December 2020

Angiogenesis and Expression of Platelet-Derived Endothelial Cell Growth Factor in Oral Squamous Cell Carcinoma

1 reference

12 December 2020

Combined analysis of vascular endothelial growth factor and platelet-derived endothelial cell growth factor expression in gastric carcinoma

1 reference

12 December 2020

Identification and comparative analysis of thymidine phosphorylase in the plasma of healthy subjects and cancer patients

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12 December 2020

The role of thymidine phosphorylase expression in the invasiveness of gastric carcinoma

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12 December 2020

Thymidine phosphorylase expression in gastric carcinoma as a marker for metastasis.

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12 December 2020

The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma

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12 December 2020

Capecitabine, alone and in combination, in the management of patients with colorectal cancer: a review of the evidence

1 reference

12 December 2020

Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis

1 reference

12 December 2020

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a disease of two genomes

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine cervical cancers

1 reference

12 December 2020

Microsomal heme oxygenase. Characterization of the enzyme

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12 December 2020

Clinicopathological and prognostic significance of thymidine phosphorylase expression in gastric carcinoma

1 reference

12 December 2020

Thymidine phosphorylase suppresses Fas-induced apoptotic signal transduction independent of its enzymatic activity

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12 December 2020

Immunohistochemical expression of thymidine phosphorylase in human endometrial cancer

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12 December 2020

Different Angiogenic Pathways in Human Cervical Cancers

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12 December 2020

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

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12 December 2020

Correlation between malignancy grade and p53 gene in relation to thymidine phosphorylase activity in colorectal cancer patients

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12 December 2020

Co-determination of the angiogenic factors thymidine phosphorylase and vascular endothelial growth factor in node-negative breast cancer: prognostic implications

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12 December 2020

Covalent linkage between nucleotides and platelet-derived endothelial cell growth factor

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12 December 2020

Vascular endothelial growth factor expression in progression of cervical cancer: correlation with thymidine phosphorylase expression, angiogenesis, tumor cell proliferation, and apoptosis.

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12 December 2020

P450 enzyme expression patterns in the NCI human tumor cell line panel

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12 December 2020

Thymidine phosphorylase induces angiogenesis in vivo and in vitro: an evaluation of possible mechanisms

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12 December 2020

A novel glial growth inhibitory factor, gliostatin, derived from neurofibroma

1 reference

12 December 2020

Up-regulated pyrimidine nucleoside phosphorylase in breast carcinoma correlates with lymph node metastasis

1 reference

12 December 2020

Angiogenesis in pancreatic carcinoma: thymidine phosphorylase expression in stromal cells and intratumoral microvessel density as independent predictors of overall and relapse-free survival

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12 December 2020

Focal expression of thymidine phosphorylase associates with CD31 positive lymphocytic aggregation and local neo-angiogenesis in non-small cell lung cancer

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12 December 2020

Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine endometrial cancers

1 reference

12 December 2020

Combination of thymidine phosphorylase gene transfer and deoxyinosine treatment greatly enhances 5-fluorouracil antitumor activity in vitro and in vivo.

1 reference

12 December 2020

Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients

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12 December 2020

Purine nucleosides as cell-specific modulators of 5-fluorouracil metabolism and cytotoxicity

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12 December 2020

Clinical implications of circulating angiogenic factors in cancer patients

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12 December 2020

High levels of thymidine phosphorylase as an independent prognostic factor in renal cell carcinoma

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12 December 2020

Purification of thymidine phosphorylase from Escherichia coli and its photoinactivation in the presence of thymine, thymidine, and some halogenated analogs

1 reference

12 December 2020

Thymidine phosphorylase in human esophageal squamous cell carcinoma

1 reference

12 December 2020

Platelet-derived endothelial cell growth factor predicts of progression and recurrence in primary epithelial ovarian cancer

1 reference

12 December 2020

Macrophage infiltration-associated thymidine phosphorylase expression correlates with increased microvessel density and poor prognosis in astrocytic tumors

1 reference

12 December 2020

Histidine protein kinases: key signal transducers outside the animal kingdom

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12 December 2020

A human SCO2 mutation helps define the role of Sco1p in the cytochrome oxidase assembly pathway

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12 December 2020

Thymidine phosphorylase expression in tumour cells and tumour response to capecitabine plus docetaxel chemotherapy in non-small cell lung cancer

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12 December 2020

Correlation between thymidine phosphorylase expression and prognosis in human renal cell carcinoma

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12 December 2020

Regulation of the Expression of the Angiogenic Enzyme Platelet-Derived Endothelial Cell Growth Factor/ Thymidine Phosphorylase in Endometrial Isolates by Ovarian Steroids and Cytokines*

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12 December 2020

Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-up

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12 December 2020

Tumor angiogenesis and expression of thymidine phosphorylase/platelet derived endothelial cell growth factor in human gastric carcinoma

1 reference

12 December 2020

Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.

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12 December 2020

Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines

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12 December 2020

Expression of thymidine phosphorylase as an indicator of poor prognosis for patients with transitional cell carcinoma of the bladder

1 reference

12 December 2020

Angiogenesis in gastric cancer: importance of the thymidine phosphorylase expression of cancer cells as an angiogenic factor

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12 December 2020

Purification and amino acid analysis of an active site peptide from thymidylate synthetase containing covalently bound 5-fluoro-2'-deoxyuridylate and methylenetetrahydrofolate.

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12 December 2020

Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study

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12 December 2020

The activity and expression of thymidine phosphorylase in human solid tumours

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12 December 2020

Correlation between tumor angiogenesis and expression of thymidine phosphorylase, and patient outcome in uterine cervical carcinoma

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12 December 2020

Thymidine and deoxyuridine accumulate in tissues of patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)

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12 December 2020

Antiviral drugs in current clinical use.

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12 December 2020

Clinicopathological and prognostic significance of thymidine phosphorylase and proliferating cell nuclear antigen in gastric carcinoma

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12 December 2020

Expression of the thymidine phosphorylase gene in epithelial ovarian cancer

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12 December 2020

Expression of platelet-derived endothelial cell growth factor and its mRNA in uterine endometrium during the menstrual cycle

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12 December 2020

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

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12 December 2020

Endothelial progenitor cells for cancer gene therapy.

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12 December 2020

Significance of thymidine phosphorylase as a marker of protumor monocytes in breast cancer

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12 December 2020

Expressions of thymidine phosphorylase (dThdPase) and vascular endothelial growth factor on angiogenesis in intestinal-type gastric carcinoma

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12 December 2020

The expression of thymidine phosphorylase suppresses spontaneous apoptosis of cancer cells in esophageal squamous cell carcinoma

1 reference

12 December 2020

The Sp1 transcription factor contributes to the tumor necrosis factor-induced expression of the angiogenic factor thymidine phosphorylase in human colon carcinoma cells

1 reference

12 December 2020

Immunohistochemical localization of platelet-derived endothelial cell growth factor expression and its relation to angiogenesis in prostate

1 reference

12 December 2020

Prognostic value of thymidine phosphorylase expression in breast carcinoma

1 reference

12 December 2020

Modes of resistance to anti-angiogenic therapy

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12 December 2020

Clinical significance of the detection of thymidine phosphorylase activity in esophageal squamous cell carcinomas

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12 December 2020

Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: in vitro and in vivo study.

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12 December 2020

Elevated plasma deoxyuridine in patients with thymidine phosphorylase deficiency

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12 December 2020

Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implications for drug design

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12 December 2020

Regional localization of the human platelet-derived endothelial cell growth factor (ECGF1) gene to chromosome 22q13

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12 December 2020

IL-1beta-induced expression of matrix metalloproteinases and gliostatin/platelet-derived endothelial cell growth factor (GLS/PD-ECGF) in a chondrosarcoma cell line (OUMS-27).

1 reference

12 December 2020

Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors

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12 December 2020

Purification and properties of an endothelial cell growth factor from human platelets

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12 December 2020

Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity

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12 December 2020

Expression of platelet-derived endothelial cell growth factor in prostatic adenocarcinoma

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12 December 2020

The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers.

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12 December 2020

Regulation of expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in human colon carcinoma cells

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12 December 2020

Induction of thymidine phosphorylase in both irradiated and shielded, contralateral human U87MG glioma xenografts: implications for a dual modality treatment using capecitabine and irradiation

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12 December 2020

The prognostic significance of thymidine phosphorylase, thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in breast carcinomas

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12 December 2020

Platelet-derived endothelial cell growth factor in keratinizing-type squamous cell uterine cervical cancer

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12 December 2020

Phosphorolysis of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted-2'-deoxyuridines by purified human thymidine phosphorylase and intact blood platelets

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12 December 2020

Platelet-derived endothelial cell growth factor expression and angiogenesis in cervical intraepithelial neoplasia and squamous cell carcinoma of the cervix.

1 reference

12 December 2020

Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer

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12 December 2020

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.

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12 December 2020

Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.

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12 December 2020

Elevated Thymidine Phosphorylase Activity in the Plasma and Ascitic Fluids of Tumor-Bearing Animals

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12 December 2020

Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma.

1 reference

12 December 2020

Angiopoietin-1 is an apoptosis survival factor for endothelial cells

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12 December 2020

Thymidine phosphorylase/platelet-derived endothelial cell growth factor (PD-ECGF) associated with prognosis in renal cell carcinoma

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12 December 2020

Enzymatic activities of uridine and thymidine phosphorylase in normal and cancerous uterine cervical tissues

1 reference

12 December 2020

Thymidine phosphorylase gene mutations in MNGIE, a human mitochondrial disorder

1 reference

12 December 2020

Tumor angiogenesis and thymidine phosphorylase expression in ovarian carcinomas including serous surface papillary adenocarcinoma of the peritoneum

1 reference

12 December 2020

Endothelial progenitor cells: new perspectives and applications in cardiovascular therapies.

1 reference

12 December 2020

The cytostatic activity of pyrimidine nucleosides is strongly modulated by Mycoplasma hyorhinis infection: Implications for cancer therapy

1 reference

12 December 2020

Thymidine phosphorylase and dihydropyrimidine dehydrogenase are predictive factors of therapeutic efficacy of capecitabine monotherapy for breast cancer-preliminary results

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12 December 2020

Expression of thymidine phosphorylase in human cervical cancer

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12 December 2020

Prognostic significance of angiogenesis in human pancreatic cancer

1 reference

12 December 2020

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project

1 reference

12 December 2020

Thymidine phosphorylase expression in human colorectal mucosa, adenoma and carcinoma: role of p53 expression

1 reference

12 December 2020

Prognostic significance of serum thymidine phosphorylase concentration in esophageal squamous cell carcinoma

1 reference

12 December 2020

A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.

1 reference

12 December 2020

Angiopoietin-1 is inversely related to thymidine phosphorylase expression in human breast cancer, indicating a role in vascular remodeling.

1 reference

12 December 2020

Thymidine phosphorylase activity in human bladder cancer: difference between superficial and invasive cancer

1 reference

12 December 2020

Co-expression of vascular endothelial growth factor and thymidine phosphorylase in endometrial cancer

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in ovarian cancers

1 reference

12 December 2020

Localization of two angiogenic growth factors (PDECGF and VEGF) in human placentae throughout gestation

1 reference

12 December 2020

Thymidine phosphorylase levels as a prognostic factor in renal cell carcinoma

1 reference

12 December 2020

Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities

1 reference

12 December 2020

Upregulation of thymidine phosphorylase in chronic glomerulonephritis and its role in tubulointerstitial injury.

1 reference

12 December 2020

Thymidine phosphorylase (platelet-derived endothelial cell growth factor), microvessel density and clinical outcome in hepatocellular carcinoma

1 reference

12 December 2020

Thymidine phosphorylase is angiogenic and promotes tumor growth.

1 reference

12 December 2020

Importance of thymidine phosphorylase expression in tumor stroma as a prognostic factor in patients with advanced colorectal carcinoma.

1 reference

12 December 2020

Up-regulation of thymidine phosphorylase expression is associated with a discrete pattern of angiogenesis in ductal carcinomasin situ of the breast

1 reference

12 December 2020

Thymidine phosphorylase expression as a prognostic marker for predicting recurrence in primary superficial bladder cancer

1 reference

12 December 2020

A role of thymidine phosphorylase and P53 tissue protein expression in biology of endometrial cancer.

1 reference

12 December 2020

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

1 reference

12 December 2020

Induction of thymidine phosphorylase by interferon and taxanes occurs only in human cancer cells with low thymidine phosphorylase activity

1 reference

12 December 2020

Kinetic studies of thymidine phosphorylase from mouse liver

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12 December 2020

Purification and properties of thymidine phosphorylase from Salmonella typhimurium

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12 December 2020

Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures

1 reference

12 December 2020

Role of thymidine phosphorylase in biomodulation of fluoropyrimidines

1 reference

12 December 2020

Clinical significance of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in transitional cell cancer

1 reference

12 December 2020

Elevated thymidine phosphorylase activity in psoriatic lesions accounts for the apparent presence of an epidermal "growth inhibitor," but is not in itself growth inhibitory

1 reference

12 December 2020

Mycoplasma fermentans infection promotes immortalization of human peripheral blood mononuclear cells in culture

1 reference

12 December 2020

Thymidine phosphorylase expression is associated with both increase of intratumoral microvessels and decrease of apoptosis in human colorectal carcinomas

1 reference

12 December 2020

Sulfasalazine down-regulates the expression of the angiogenic factors platelet-derived endothelial cell growth factor/thymidine phosphorylase and interleukin-8 in human monocytic-macrophage THP1 and U937 cells

1 reference

12 December 2020

Angiogenic activity of enzymes.

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12 December 2020

Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides

1 reference

12 December 2020

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1 reference

12 December 2020

The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action

1 reference

12 December 2020

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study

1 reference

12 December 2020

Neurotrophic action of gliostatin on cortical neurons. Identity of gliostatin and platelet-derived endothelial cell growth factor

1 reference

12 December 2020

Is XELOX equivalent to FOLFOX or other continuous-infusion 5-fluorouracil chemotherapy in metastatic colorectal cancer?

1 reference

12 December 2020

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression correlated with tumor angiogenesis and macrophage infiltration in colorectal cancer

1 reference

12 December 2020

Angiogenesis and platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in cervical cancer

1 reference

12 December 2020

Resistance of colorectal cancer cells to 5-FUdR and 5-FU caused by Mycoplasma infection

1 reference

12 December 2020

Thymidine phosphorylase gene mutation is not a primary cause of mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)

1 reference

12 December 2020

Prognostic role of thymidylate synthase, thymidine phosphorylase/platelet-derived endothelial cell growth factor, and proliferation markers in colorectal cancer

1 reference

12 December 2020

Thymidine phosphorylase inhibitors: recent developments and potential therapeutic applications

1 reference

12 December 2020

The amino acid sequence of D-ribose-binding protein from Escherichia coli K12.

1 reference

12 December 2020

The effect of a thymidine phosphorylase inhibitor on angiogenesis and apoptosis in tumors

1 reference

12 December 2020

Different angiogenic pathways characterize superficial and invasive bladder cancer

1 reference

12 December 2020

Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase

1 reference

12 December 2020

Stromal angiogenesis in human glioma: A role of platelet-derived endothelial cell growth factor

1 reference

12 December 2020

Thymidine phosphorylase expression in tumor stroma of uterine cervical carcinomas: histological features and microvessel density

1 reference

12 December 2020

Micro-vessel density and the expression of vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor (PdEGF) in classical Hodgkin lymphoma (HL).

1 reference

12 December 2020

Prediction of the effect of capecitabine in gastric cancer by immunohistochemical staining of thymidine phosphorylase and dihydropyrimidine dehydrogenase

1 reference

12 December 2020

Platelet-derived endothelial cell growth factor/thymidine phosphorylase concentrations differ in small cell and non-small cell lung cancer

1 reference

12 December 2020

Expression of thymidine phosphorylase is associated with a poor prognosis in patients with ductal adenocarcinoma of the pancreas.

1 reference

12 December 2020

Mutations in SCO2 are associated with a distinct form of hypertrophic cardiomyopathy and cytochrome c oxidase deficiency

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity

1 reference

12 December 2020

Prediction of in vivo drug-drug interactions based on mechanism-based inhibition from in vitro data: inhibition of 5-fluorouracil metabolism by (E)-5-(2-Bromovinyl)uracil

1 reference

12 December 2020

Prevalence of mycoplasma conserved DNA in malignant ovarian cancer detected using sensitive PCR-ELISA.

1 reference

12 December 2020

Angiogenesis in life, disease and medicine

1 reference

12 December 2020

Autocrine induction of gliostatin/platelet-derived endothelial cell growth factor (GLS/PD-ECGF) and GLS-induced expression of matrix metalloproteinases in rheumatoid arthritis synoviocytes

1 reference

12 December 2020

Microvessel density and expression of vascular endothelial growth factor, basic fibroblast growth factor, and platelet-derived endothelial growth factor in oral squamous cell carcinomas

1 reference

12 December 2020

Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine

1 reference

12 December 2020

The activity of thymidine phosphorylase as a new ovarian tumor marker

1 reference

12 December 2020

Clinical implication of expression of platelet-derived endothelial cell growth factor (PD-ECGF) in metastatic lesions of uterine cervical cancers

1 reference

12 December 2020

Thymidine phosphorylase expression is predominantly observed in stroma of well-differentiated adenocarcinoma of endometrium and correlates with a frequency of vascular involvement

1 reference

12 December 2020

Immunohistochemical expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in squamous cell carcinoma of the esophagus

1 reference

12 December 2020

Thymidine phosphorylase gene transfer inhibits vascular smooth muscle cell proliferation by upregulating heme oxygenase-1 and p27KIP1.

1 reference

12 December 2020

Expression of angiogenic factors predicts response to chemoradiotherapy and prognosis of oesophageal squamous cell carcinoma

1 reference

12 December 2020

Significance of platelet-derived endothelial cell growth factor in the angiogenesis of human gastric cancer

1 reference

12 December 2020

Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice

1 reference

12 December 2020

Inhibition of metastasis of tumor cells overexpressing thymidine phosphorylase by 2-deoxy-L-ribose

1 reference

12 December 2020

Endothelial cell migration is induced by soluble P-selectin

1 reference

12 December 2020

7-Deazaxanthine, a novel prototype inhibitor of thymidine phosphorylase

1 reference

12 December 2020

Effect of heme and heme oxygenase-1 on vascular endothelial growth factor synthesis and angiogenic potency of human keratinocytes

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor in non-small cell lung carcinomas: relationship to various biological factors.

1 reference

12 December 2020

Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase

1 reference

12 December 2020

Role of mTOR in solid tumor systems: a therapeutical target against primary tumor growth, metastases, and angiogenesis

1 reference

12 December 2020

Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism

1 reference

12 December 2020

Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose

1 reference

12 December 2020

The expression of platelet-derived endothelial cell growth factor in human bladder cancer

1 reference

12 December 2020

Mechanisms by which tumor cells and monocytes expressing the angiogenic factor thymidine phosphorylase mediate human endothelial cell migration.

1 reference

12 December 2020

Tumor angiogenesis: therapeutic implications

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12 December 2020

Mechanism-based inhibition of thymidylate synthase by 5-(trifluoromethyl)-2'-deoxyuridine 5'-monophosphate

1 reference

12 December 2020

Immunohistochemical localization of thymidine phosphorylase in gastric cancer: is there a role of the differential expression in tumor cells and associated stromal cells?

1 reference

12 December 2020

Relationship between matrix metalloproteinase expression and tumor angiogenesis in human breast carcinoma

1 reference

12 December 2020

Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression

1 reference

12 December 2020

p37 Induces tumor invasiveness

1 reference

12 December 2020

Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis

1 reference

12 December 2020

5-Fluorouracil: mechanisms of action and clinical strategies

1 reference

12 December 2020

Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy

1 reference

12 December 2020

59 Thymidine phosphorylase from Escherichia coli

1 reference

12 December 2020

Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution

1 reference

12 December 2020

Expression of thymidine phosphorylase and VEGF in esophageal squamous cell carcinoma

1 reference

12 December 2020

The value of platelet-derived endothelial cell growth factor as a novel predictor of advancement of uterine cervical cancers

1 reference

12 December 2020

Expression of thymidine phosphorylase correlates with microvessel density in prostate cancer.

1 reference

12 December 2020

Expression of angiogenic factor thymidine phosphorylase and angiogenesis in human atherosclerosis

1 reference

12 December 2020

Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase.

1 reference

12 December 2020

X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts

1 reference

12 December 2020

Meta-analysis of hepatic arterial infusion for unresectable liver metastases from colorectal cancer: the end of an era?

1 reference

12 December 2020

The role of thymidine phosphorylase (TP) mRNA expression in angiogenesis of prostate cancer.

1 reference

12 December 2020

Kinetic analysis of novel multisubstrate analogue inhibitors of thymidine phosphorylase.

1 reference

12 December 2020

Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3.

1 reference

12 December 2020

Suppression of thymidine phosphorylase expression by promoter methylation in human cancer cells lacking enzyme activity

1 reference

12 December 2020

Relationship of elevated tumour thymidine phosphorylase in node-positive breast carcinomas to the effects of adjuvant CMF

1 reference

12 December 2020

Integrin-dependent activation of the p70 ribosomal S6 kinase signaling pathway

1 reference

12 December 2020

Adventitial delivery of platelet-derived endothelial cell growth factor gene prevented intimal hyperplasia of vein graft

1 reference

12 December 2020

Mycoplasmas and oncogenesis: persistent infection and multistage malignant transformation

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor in oral and oropharyngeal carcinoma.

1 reference

12 December 2020

Thymidine phosphorylase expression in endometrial carcinomas

1 reference

12 December 2020

Expressions of angiogenic factors in pancreatic ductal carcinoma: a correlative study with clinicopathologic parameters and patient survival

1 reference

12 December 2020

Thymidine kinase and thymidine phosphorylase level as the main predictive parameter for sensitivity to TAS-102 in a mouse model.

1 reference

12 December 2020

Do mycoplasmas cause human cancer?

1 reference

12 December 2020

Synovial inflammation and hyperplasia induced by gliostatin/platelet-derived endothelial cell growth factor in rabbit knees

1 reference

12 December 2020

Biological role of thymidine phosphorylase in human astrocytic tumors

1 reference

12 December 2020

The clinical pharmacology of 5-trifluoromethyl-2'-deoxyuridine.

1 reference

12 December 2020

2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.

1 reference

12 December 2020

The enzymatic synthesis of nucleosides. I. Thymidine phosphorylase in mammalian tissue.

1 reference

12 December 2020

Assessment of archived paraffin-embedded cervical condyloma tissues for mycoplasma-conserved DNA using sensitive PCR-ELISA.

1 reference

12 December 2020

Thymidine phosphorylase activity and angiogenesis in gastric cancer

1 reference

12 December 2020

Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma

1 reference

12 December 2020

Prognostic role of angiogenesis and its correlations with thymidine phosphorylase and p53 expression in ductal adenocarcinoma of the pancreas.

1 reference

12 December 2020

Clinical impact of thymidine phosphorylase expression in gastric cancer.

1 reference

12 December 2020

Thymidine phoshorylase expression in breast cancer: the prognostic significance and its association with other angiogenesis related proteins and extracellular matrix components

1 reference

12 December 2020

A phase I safety, tolerability, and pharmacokinetic study of enzastaurin combined with capecitabine in patients with advanced solid tumors

1 reference

12 December 2020

Enzymes of pyrimidine deoxyribonucleotide metabolism in Mycoplasma mycoides subsp. mycoides

1 reference

12 December 2020

VEGF as a key mediator of angiogenesis in cancer

1 reference

12 December 2020

Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.

1 reference

12 December 2020

Prognostic significance of platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in stage pT1 G3 bladder cancer

1 reference

12 December 2020

Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer

1 reference

12 December 2020

Prognostic significance of expression of thymidine phosphorylase and vascular endothelial growth factor in human gastric carcinoma

1 reference

12 December 2020

Angiogenesis: an organizing principle for drug discovery?

1 reference

12 December 2020

Mycoplasma infections and different human carcinomas.

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer

1 reference

12 December 2020

Thymidine Phosphorylase Mediates the Sensitivity of Human Colon Carcinoma Cells to 5-Fluorouracil

1 reference

12 December 2020

Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase

1 reference

12 December 2020

Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease.

1 reference

12 December 2020

Expression of thymidine phosphorylase in epithelial ovarian cancer: correlation with angiogenesis, apoptosis, and ultrasound-derived peak systolic velocity

1 reference

12 December 2020

Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors.

1 reference

12 December 2020

Thymidine phosphorylase expression is associated with response to capecitabine plus irinotecan in patients with metastatic colorectal cancer.

1 reference

12 December 2020

Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors

1 reference

12 December 2020

Capecitabine: a review

1 reference

12 December 2020

Tumor growth pattern and thymidine phosphorylase expression are related with the risk of hematogenous metastasis in patients with Astler Coller B1/B2 colorectal carcinoma

1 reference

12 December 2020

Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers

1 reference

12 December 2020

Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma

1 reference

12 December 2020

Expression of basic fibroblast growth factor is associated with a good outcome in patients with squamous cell carcinoma of the esophagus.

1 reference

12 December 2020

The significance of thymidine phosphorylase/platelet-derived endothelial cell growth factor activity in renal cell carcinoma

1 reference

12 December 2020

5'-O-Tritylated Nucleoside Derivatives: Inhibition of Thymidine Phosphorylase and Angiogenesis

1 reference

12 December 2020

Gliostatin/platelet-derived endothelial cell growth factor as a clinical marker of rheumatoid arthritis and its regulation in fibroblast-like synoviocytes

1 reference

12 December 2020

Overexpression of the angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase in psoriatic epidermis

1 reference

12 December 2020

Prognostic significance of thymidine phosphorylase and p53 co-expression in esophageal squamous cell carcinoma.

1 reference

12 December 2020

Correlation between expression levels of thymidine phosphorylase (dThdPase) and clinical features in human gastric carcinoma

1 reference

12 December 2020

Purification of thymidine phosphorylase from human amniochorion

1 reference

12 December 2020

Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration

1 reference

12 December 2020

Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results

1 reference

12 December 2020

Mechanism of trifluorothymidine potentiation of oxaliplatin-induced cytotoxicity to colorectal cancer cells

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor in bladder carcinoma

1 reference

12 December 2020

Localization of platelet-derived endothelial cell growth factor in human placenta and purification of an alternatively processed form.

1 reference

12 December 2020

Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

1 reference

12 December 2020

Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study

1 reference

12 December 2020

The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation

1 reference

12 December 2020

Suppression of metastasis by thymidine phosphorylase inhibitor

1 reference

12 December 2020

Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy

1 reference

12 December 2020

Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human p

1 reference

12 December 2020

Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth

1 reference

12 December 2020

1 reference

12 December 2020

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

1 reference

12 December 2020

PD-ECGF, bFGF, and VEGF expression in non-small cell lung carcinomas and their association with lymph node metastasis

1 reference

12 December 2020

Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer

1 reference

12 December 2020

Vascular endothelial growth factor and platelet-derived endothelial cell growth factor expression are implicated in the angiogenesis of endometrial cancer

1 reference

12 December 2020

Capecitabine in combination with novel targeted agents in the management of metastatic breast cancer: underlying rationale and results of clinical trials

1 reference

12 December 2020

Aberrant production of gliostatin/platelet-derived endothelial cell growth factor in rheumatoid synovium

1 reference

12 December 2020

Prospective randomised trial comparing fluorouracil versus doxifluridine for the treatment of advanced colorectal cancer

1 reference

12 December 2020

Thymidine phosphorylase expression in tumor-infiltrating macrophages may be correlated with poor prognosis in uterine endometrial cancer

1 reference

12 December 2020

Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors.

1 reference

12 December 2020

Identification of the angiogenic endothelial-cell growth factor-1/thymidine phosphorylase as a potential target for immunotherapy of cancer

1 reference

12 December 2020

Selected combination therapy with sorafenib: a review of clinical data and perspectives in advanced solid tumors.

1 reference

12 December 2020

Thymidine Phosphorylase from Escherichia coli. Properties and Kinetics

1 reference

12 December 2020

Antitumor activity and low intestinal toxicity of S-1, a new formulation of oral tegafur, in experimental tumor models in rats

1 reference

12 December 2020

Tumorigenesis and the angiogenic switch

1 reference

12 December 2020

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

1 reference

12 December 2020

The role of blood platelets in nucleoside metabolism: assay, cellular location and significance of thymidine phosphorylase in human blood

1 reference

12 December 2020

Mitochondrial neurogastrointestinal encephalomyopathy: an autosomal recessive disorder due to thymidine phosphorylase mutations

1 reference

12 December 2020

Angiogenesis as a therapeutic target

1 reference

12 December 2020

Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes

1 reference

12 December 2020

Tumor inhibitory effects of a new fluorouracil derivative: 5'-deoxy-5-fluorouridine

1 reference

12 December 2020

Thymidine phosphorylase activity in nonsmall cell lung carcinoma tissues

1 reference

12 December 2020

Effects of platelet-derived endothelial cell growth factor/thymidine phosphorylase, substrate, and products in a three-dimensional model of angiogenesis

1 reference

12 December 2020

2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9.

1 reference

12 December 2020

Role of thymidine phosphorylase and orotate phosphoribosyltransferase mRNA expression and its ratio to dihydropyrimidine dehydrogenase in the prognosis and clinicopathological features of patients with pancreatic cancer

1 reference

12 December 2020

Human platelet-derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase

1 reference

12 December 2020

Phase 1 study of TAS-102 administered once daily on a 5-day-per-week schedule in patients with solid tumors.

1 reference

12 December 2020

Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase

1 reference

12 December 2020

Fluorinated pyrimidines, a new class of tumour-inhibitory compounds

1 reference

12 December 2020

Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis

1 reference

12 December 2020

Expression of thymidine phosphorylase and vascular endothelial growth factor in epithelial ovarian cancer: correlation with angiogenesis and progression of the tumor

1 reference

12 December 2020

Expression of the angiogenic factor thymidine phosphorylase in THP-1 monocytes: induction by autocrine tumor necrosis factor-alpha and inhibition by aspirin

1 reference

12 December 2020

Thymidine phosphorylase inhibits apoptosis induced by cisplatin

1 reference

12 December 2020

Modulation of Transcription Factor Sp1 by cAMP-dependent Protein Kinase

1 reference

12 December 2020

Quantitative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase in renal cell carcinoma

1 reference

12 December 2020

Gliostatin/thymidine phosphorylase-regulated vascular endothelial growth-factor production in human fibroblast-like synoviocytes

1 reference

12 December 2020

Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines

1 reference

12 December 2020

Thymidine phosphorylase expression causes both the increase of intratumoral microvessels and decrease of apoptosis in human esophageal carcinomas

1 reference

12 December 2020

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in macrophages correlates with tumor angiogenesis and prognosis in invasive breast cancer

1 reference

12 December 2020

Role of tumor angiogenesis in gallbladder carcinoma: with special reference to thymidine phosphorylase

1 reference

12 December 2020

Endocrinology and paracrinology: The presence of platelet-derived endothelial cell growth factor in human endometrium and its characteristic expression during the menstrual cycle and early gestational period

1 reference

12 December 2020

Expression of platelet-derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma

1 reference

12 December 2020

Sensitivity of human KB cells expressing platelet-derived endothelial cell growth factor to pyrimidine antimetabolites

1 reference

12 December 2020

Modulation of vascular endothelial growth factor and thymidine phosphorylase in normal human endometrial stromal cells

1 reference

12 December 2020

Occurrence of hematogenous metastasis and serum levels of thymidine phosphorylase in colorectal cancer

1 reference

12 December 2020

Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells

1 reference

12 December 2020

Thymidine phosphorylase/platelet-derived endothelial cell growth factor is upregulated in advanced solid types of gastric cancer

1 reference

12 December 2020

A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells

1 reference

12 December 2020

Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents.

1 reference

12 December 2020

Identifiers

DOI

10.1002/MED.20159

1 reference

5 August 2017

0 references

1 reference