(Q34749886)

4 August 2017

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title

The role of metal ions in RNA catalysis (English)

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4 August 2017

Martha J Fedor

1

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4 August 2017

publication date

1 June 2002

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Current Opinion in Structural Biology

4 August 2017

published in

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4 August 2017

volume

12

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4 August 2017

issue

3

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4 August 2017

page(s)

289-295

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Enzyme-Catalyzed Phosphoryl Transfer Reactions

4 August 2017

cites work

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7 January 2021

Crystal structure of a hepatitis delta virus ribozyme

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7 January 2021

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

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7 January 2021

Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis

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7 January 2021

Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions

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7 January 2021

A general two-metal-ion mechanism for catalytic RNA

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7 January 2021

Making the most of metal ions

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7 January 2021

Structure and function of the small ribozymes

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7 January 2021

Structure and function of the hairpin ribozyme

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7 January 2021

Recent advances in the elucidation of the mechanisms of action of ribozymes

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7 January 2021

Ribozyme structures and mechanisms

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7 January 2021

Metal ions in ribozyme folding and catalysis

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7 January 2021

Probing the role of metal ions in RNA catalysis: kinetic and thermodynamic characterization of a metal ion interaction with the 2'-moiety of the guanosine nucleophile in the Tetrahymena group I ribozyme

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7 January 2021

Three metal ions at the active site of the Tetrahymena group I ribozyme

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7 January 2021

A new metal ion interaction in the Tetrahymena ribozyme reaction revealed by double sulfur substitution

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7 January 2021

Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction

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7 January 2021

Metal ion interaction with cosubstrate in self-splicing of group I introns

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7 January 2021

Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom

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7 January 2021

Bond order and charge localization in nucleoside phosphorothioates

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7 January 2021

Metal ion catalysis during splicing of premessenger RNA

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7 January 2021

Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns

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7 January 2021

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

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7 January 2021

Kinetic characterization of the second step of group II intron splicing: role of metal ions and the cleavage site 2'-OH in catalysis

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7 January 2021

Metal ion binding sites in a group II intron core

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7 January 2021

Mapping divalent metal ion binding sites in a group II intron by Mn(2+)- and Zn(2+)-induced site-specific RNA cleavage

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7 January 2021

The question remains: is the spliceosome a ribozyme?

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7 January 2021

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

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7 January 2021

Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis

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7 January 2021

Ribonuclease P: a ribonucleoprotein enzyme

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7 January 2021

Role of metal ions in the hydrolysis reaction catalyzed by RNase P RNA from Bacillus subtilis

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7 January 2021

Effects of phosphorothioate modifications on precursor tRNA processing by eukaryotic RNase P enzymes

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7 January 2021

NMR spectroscopic evidence for Mn(2+)(Mg(2+)) binding to a precursor-tRNA microhelix near the potential RNase P cleavage site

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7 January 2021

Helix P4 is a divalent metal ion binding site in the conserved core of the ribonuclease P ribozyme

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7 January 2021

Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage

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7 January 2021

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7 January 2021

A crystallographic study of metal-binding to yeast phenylalanine transfer RNA

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7 January 2021

Metallobiochemistry of RNA. Co(NH3)63+ as a probe for Mg2+(aq) binding sites

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7 January 2021

Cobalt hexammine inhibition of the hammerhead ribozyme

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7 January 2021

General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme

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7 January 2021

The hammerhead cleavage reaction in monovalent cations

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7 January 2021

Effects of cobalt hexammine on folding and self-cleavage of the Neurospora VS ribozyme

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7 January 2021

Ribozyme activity in the genomic and antigenomic RNA strands of hepatitis delta virus

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7 January 2021

Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism

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7 January 2021

The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone

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7 January 2021

Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.

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7 January 2021

A re-investigation of the thio effect at the hammerhead cleavage site

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7 January 2021

Hammerhead cleavage of the phosphorodithioate linkage

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7 January 2021

Stabilization of RNA structure by Mg ions. Specific and non-specific effects.

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7 January 2021

Bimolecular exon ligation by the human spliceosome

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7 January 2021

10.1016/S0959-440X(02)00324-X

Identifiers

DOI

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4 August 2017

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