(Q34661844)

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Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism

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Europe PubMed Central

PubMed publication ID

3 August 2017

Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

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Natalia Malek

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Katarzyna Starowicz-Bubak

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Katarzyna Starowicz

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Wioletta Makuch

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Wioletta Makuch

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Vincenzo Di Marzo

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Vincenzo Di Marzo

11

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Michał Korostyński

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Michal Korostynski

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Europe PubMed Central

PubMed publication ID

3 August 2017

Barbara Przewłocka

10

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Barbara Przewlocka

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Europe PubMed Central

PubMed publication ID

3 August 2017

Luciano De Petrocellis

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Luciano De Petrocellis

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Europe PubMed Central

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3 August 2017

Luigia Cristino

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Luigia Cristino

9

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Michal Slezak

5

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Europe PubMed Central

PubMed publication ID

3 August 2017

Magdalena Zychowska

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3 August 2017

Stefania Petrosino

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Europe PubMed Central

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3 August 2017

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3 April 2013

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Europe PubMed Central

PubMed publication ID

3 August 2017

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Europe PubMed Central

PubMed publication ID

3 August 2017

8

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Europe PubMed Central

PubMed publication ID

3 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

e60040

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Europe PubMed Central

PubMed publication ID

3 August 2017

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Creative Commons Attribution 4.0 International

3 April 2013

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April 2022 Public Data File from Crossref

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0 references

Why do cannabinoid receptors have more than one endogenous ligand?

1 reference

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7 July 2018

Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide

1 reference

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7 July 2018

Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases.

1 reference

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7 July 2018

Is 15-LOX-1 a tumor suppressor?

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Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability

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7 July 2018

15-Lipoxygenase eicosanoids are the putative ligands for vanilloid receptors and peroxisome proliferator-activated receptors (PPARs).

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Cannabinoid 1 (CB1) Receptor - Pharmacology, Role in Pain and Recent Developments in Emerging CB1 Agonists

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7 July 2018

Role of TRP Channels in Pain Sensation

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Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms.

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The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation.

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7 July 2018

Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain

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The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products

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7 July 2018

The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB(1), TRPV1 and PPARgamma receptors and neurotrophic factors

1 reference

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7 July 2018

TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications

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7 July 2018

Biochemistry and pharmacology of endovanilloids

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7 July 2018

Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals.

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7 July 2018

Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists

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7 July 2018

Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism

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7 July 2018

Anandamide and vanilloid TRPV1 receptors

1 reference

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7 July 2018

Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616060

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A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation

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7 July 2018

Endovanilloid signaling in pain

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7 July 2018

Endocannabinoids and pain: spinal and peripheral analgesia in inflammation and neuropathy

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7 July 2018

A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616060

7 July 2018

The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism

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Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens

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Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist

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Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells

1 reference

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Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide

1 reference

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Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase

1 reference

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Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation

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Ethical guidelines for investigations of experimental pain in conscious animals

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A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

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Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060040

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Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060040

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Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury

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21 January 2018

FAAH and anandamide: is 2-AG really the odd one out?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060040

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Analgesic properties of oleoylethanolamide (OEA) in visceral and inflammatory pain

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Oleoylethanolamide excites vagal sensory neurones, induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1.

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21 January 2018

Endocannabinoids: synthesis and degradation

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060040

21 January 2018

15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060040

21 January 2018

Chronic catheterization of the spinal subarachnoid space

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060040

21 January 2018

Methylation and acetylation of 15-hydroxyanandamide modulate its interaction with the endocannabinoid system.

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26 October 2018

Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid typ

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Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases.

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Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide.

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26 October 2018

Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells

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26 October 2018

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRP channels and pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23573230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal anandamide produces analgesia in neuropathic rats: Possible CB1- and TRPV1-mediated mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/23573230

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0060040

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2013PLoSO...860040S

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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