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Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect.
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Europe PubMed Central
PMC publication ID
1472592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
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28 January 2020
title
Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect
(English)
1 reference
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
author
Yasumasa Iwatani
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1
1 reference
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
author name string
Hiroaki Takeuchi
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2
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Klaus Strebel
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3
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Judith G Levin
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4
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PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
language of work or name
English
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publication date
1 June 2006
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Europe PubMed Central
PMC publication ID
1472592
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
volume
80
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
issue
12
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
page(s)
5992-6002
1 reference
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Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1472592/fullTextXML
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Monomeric APOBEC3G is catalytically active and has antiviral activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Nucleic acid chaperone activity of HIV-1 nucleocapsid protein: critical role in reverse transcription and molecular mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Viral RNA is required for the association of APOBEC3G with human immunodeficiency virus type 1 nucleoprotein complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Cytidine deamination and resistance to retroviral infection: towards a structural understanding of the APOBEC proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Production of infectious SIVagm from human cells requires functional inactivation but not viral exclusion of human APOBEC3G.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
APOBEC3G incorporation into human immunodeficiency virus type 1 particles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular Stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Virology. Weapons of mutational destruction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Death by deamination: a novel host restriction system for HIV-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
DNA deamination mediates innate immunity to retroviral infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Hypermutation of HIV-1 DNA in the Absence of the Vif Protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
DNA methylation in health and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Role of Vif in human immunodeficiency virus type 1 reverse transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Human immunodeficiency virus type 1 Vif does not influence expression or virion incorporation of gag-, pol-, and env-encoded proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Human immunodeficiency virus type 1 nucleocapsid protein reduces reverse transcriptase pausing at a secondary structure near the murine leukemia virus polypurine tract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Cytosine nucleoside/nucleotide deaminases and apolipoprotein B mRNA editing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Defects in primer-template binding, processive DNA synthesis, and RNase H activity associated with chimeric reverse transcriptases having the murine leukemia virus polymerase domain joined to Escherichia coli RNase H.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The sor gene of HIV-1 is required for efficient virus transmission in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
The HIV 'A' (sor) gene product is essential for virus infectivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Gag proteins of the highly replicative MN strain of human immunodeficiency virus type 1: posttranslational modifications, proteolytic processings, and complete amino acid sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
7 July 2018
Complementary function of the two catalytic domains of APOBEC3G.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
The Vif Protein of HIV Triggers Degradation of the Human Antiretroviral DNA Deaminase APOBEC3G
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
HIV-1 Vif: counteracting innate antiretroviral defenses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
Incorporation of uracil into minus strand DNA affects the specificity of plus strand synthesis initiation during lentiviral reverse transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472592
retrieved
26 October 2018
Identifiers
DOI
10.1128/JVI.02680-05
1 reference
stated in
Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
Fatcat ID
release_rpdhhiswofe2feqrrryi57iv4i
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/rpdhhiswofe2feqrrryi57iv4i
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
1472592
1 reference
stated in
Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PubMed publication ID
16731938
1 reference
stated in
Europe PubMed Central
PMC publication ID
1472592
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16731938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
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