(Q34650970)

3 August 2017

title

Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator (English)

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3 August 2017

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6

Evan Y Snyder

1 reference

3 August 2017

Jianxue Li

1

1 reference

3 August 2017

Yinghua Ma

2

1 reference

3 August 2017

Yang D Teng

3

1 reference

3 August 2017

Kangni Zheng

4

1 reference

3 August 2017

Timothy K Vartanian

5

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3 August 2017

Richard L Sidman

7

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3 August 2017

language of work or name

English

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publication date

8 May 2006

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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3 August 2017

volume

103

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3 August 2017

issue

20

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3 August 2017

page(s)

7847-7852

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

3 August 2017

1 reference

Fibrin-modifying serine proteases thrombin, tPA, and plasmin in ischemic stroke: a review

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Regulation of synaptic transmission by mitochondrial ion channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Patterned Purkinje cell death in the cerebellum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Regulation of cell survival by secreted proneurotrophins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Trk receptors: mediators of neurotrophin action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

The mitochondrial permeability transition pore and its role in cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

The murine voltage-dependent anion channel gene family. Conserved structure and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Retinal degeneration in the nervous mutant mouse. I. Light microscopic cytopathology and changes in the interphotoreceptor matrix

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Changes in neuronal mitochondrial shape in brains of nervous mutant mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Histochemical demonstration of mitochondrial dehydrogenases in developing normal and nervous mutant mouse Purkinje cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Is tissue plasminogen activator a threat to neurons?

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Matrix-degrading enzymes tissue plasminogen activator and matrix metalloprotease-3 in the hypothalamo-neurohypophysial system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Microglia promote the death of developing Purkinje cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Tissue plasminogen activator expression in the embryonic nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

The TrkC receptor is transiently localized to Purkinje cell dendrites during outgrowth and maturation in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Rapid formation and remodeling of postsynaptic densities in developing dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Interaction of mitochondrial voltage-dependent anion channel from rat brain with plasminogen protein leads to partial closure of the channel

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Inhibition of protein kinase C prevents Purkinje cell death but does not affect axonal regeneration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472533

Effects of the murine mutation 'nervous' on neurons in cerebellum and dorsal cochlear nucleus

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

A high-resolution genetic map of the nervous locus on mouse chromosome 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

Intercellular adhesion molecule-1 is upregulated via the protein kinase C pathway in human thyroid carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

The Voltage-dependent Anion Channel Is a Receptor for Plasminogen Kringle 5 on Human Endothelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602440103

NADH regulates the gating of VDAC, the mitochondrial outer membrane channel

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16682647

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0602440103

1 reference

3 August 2017

0 references

1 reference

3 August 2017

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