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Mitochondria: regulating the inevitable.
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Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
review article
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Europe PubMed Central
title
Mitochondria: regulating the inevitable
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
author
Dominic James
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Jean-Claude Martinou
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
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9 November 2019
author name string
P A Parone
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
publication date
1 February 2002
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Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Biochimie
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
84
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
2-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
105-111
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
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7 January 2021
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Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists
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7 January 2021
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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
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Crossref
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7 January 2021
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Bim: a novel member of the Bcl-2 family that promotes apoptosis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
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Crossref
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7 January 2021
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Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
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7 January 2021
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PUMA, a novel proapoptotic gene, is induced by p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
1 reference
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Crossref
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7 January 2021
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Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.
1 reference
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7 January 2021
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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
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Crossref
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7 January 2021
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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
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7 January 2021
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Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
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Crossref
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7 January 2021
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WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
1 reference
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Crossref
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7 January 2021
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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
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7 January 2021
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inferred from DOI database lookup
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9 and APAF-1 form an active holoenzyme
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
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inferred from DOI database lookup
IAP family proteins--suppressors of apoptosis
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Endonuclease G is an apoptotic DNase when released from mitochondria
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of mitochondrial apoptosis-inducing factor
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis
1 reference
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Crossref
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7 January 2021
based on heuristic
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Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Primers for mitochondrial DNA replication generated by endonuclease G.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial endonuclease G is important for apoptosis in C. elegans.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax directly induces release of cytochrome c from isolated mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Bax channel-forming activity by Bcl-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-x(L) forms an ion channel in synthetic lipid membranes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Channel formation by antiapoptotic protein Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ion channel activity of the BH3 only Bcl-2 family member, BID.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mitochondrial permeability transition pore and its role in cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in factor-dependent haematopoietic cells is linked to calcium-sensitive mitochondrial rearrangements and cytoskeletal modulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A subpopulation of mitochondria prevents cytosolic calcium overload in endothelial cells after cold ischemia/reperfusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas-induced B cell apoptosis requires an increase in free cytosolic magnesium as an early event
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heat Shock Protein 70 Inhibits Caspase-Dependent and -Independent Apoptosis in Jurkat T Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrating cytosolic calcium signals into mitochondrial metabolic responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Feedback inhibition of sodium/calcium exchange by mitochondrial calcium accumulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 does not inhibit the permeability transition pore in mouse liver mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Bcl-2 suppresses the calcium activation of a mitochondrial megachannel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death commitment point is advanced by axotomy in sympathetic neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and cell death. Mechanistic aspects and methodological issues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chloromethyltetramethylrosamine (Mitotracker Orange) induces the mitochondrial permeability transition and inhibits respiratory complex I. Implications for the mechanism of cytochrome c release.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiolipin provides specificity for targeting of tBid to mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Bcl-2 protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 family members and the mitochondria in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria: execution central
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0300-9084%2802%2901380-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0300-9084(02)01380-9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PubMed publication ID
12022941
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12022941
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12022941%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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